Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACH33_RS12030 Genome accession   NZ_CP014140
Coordinates   2446744..2447985 (-) Length   413 a.a.
NCBI ID   WP_057899239.1    Uniprot ID   -
Organism   Aneurinibacillus sp. XH2     
Function   unknown (predicted from homology)   
Unclear

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2415862..2491106 2446744..2447985 within 0


Gene organization within MGE regions


Location: 2415862..2491106
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACH33_RS11880 (ACH33_11885) - 2417069..2417908 (-) 840 WP_082706192.1 protein phosphatase 2C domain-containing protein -
  ACH33_RS11885 (ACH33_11890) - 2417917..2418447 (-) 531 WP_057899216.1 FHA domain-containing protein -
  ACH33_RS11890 (ACH33_11895) - 2418490..2419074 (-) 585 WP_236781876.1 FHA domain-containing protein -
  ACH33_RS11895 (ACH33_11900) - 2419134..2419586 (-) 453 WP_057899218.1 DnaJ domain-containing protein -
  ACH33_RS11900 (ACH33_11905) - 2419766..2420191 (-) 426 WP_057899219.1 hypothetical protein -
  ACH33_RS11905 (ACH33_11910) - 2420377..2422542 (-) 2166 WP_057900357.1 hypothetical protein -
  ACH33_RS11910 (ACH33_11915) - 2423525..2424433 (-) 909 WP_236781877.1 serine/threonine-protein kinase -
  ACH33_RS11915 (ACH33_11920) cotE 2424542..2424787 (-) 246 WP_057899221.1 outer spore coat protein CotE -
  ACH33_RS11920 (ACH33_11925) - 2425020..2425241 (+) 222 WP_057899222.1 hypothetical protein -
  ACH33_RS11925 (ACH33_11930) - 2425332..2425877 (+) 546 WP_057899223.1 RNA polymerase sigma factor SigX -
  ACH33_RS11930 (ACH33_11935) - 2425874..2427055 (+) 1182 WP_057899224.1 zf-HC2 domain-containing protein -
  ACH33_RS11935 (ACH33_11940) - 2427122..2428093 (+) 972 WP_057899225.1 ABC transporter ATP-binding protein -
  ACH33_RS11940 (ACH33_11945) - 2428065..2428937 (+) 873 WP_057900358.1 ABC transporter permease subunit -
  ACH33_RS11945 (ACH33_11950) - 2429048..2429509 (-) 462 WP_057900359.1 YlbF family regulator -
  ACH33_RS11950 (ACH33_11955) miaB 2429517..2431037 (-) 1521 WP_082706036.1 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB -
  ACH33_RS11955 (ACH33_11960) - 2431296..2431751 (-) 456 WP_057899226.1 chemotaxis protein CheX -
  ACH33_RS11965 (ACH33_11970) - 2432433..2433017 (-) 585 WP_236781878.1 class I SAM-dependent methyltransferase -
  ACH33_RS11970 (ACH33_11975) - 2433014..2433754 (-) 741 WP_057899228.1 MBL fold metallo-hydrolase -
  ACH33_RS11975 (ACH33_11980) - 2433901..2434767 (-) 867 WP_057899229.1 2-oxoacid:ferredoxin oxidoreductase subunit beta -
  ACH33_RS11980 (ACH33_11985) - 2434769..2436505 (-) 1737 WP_057899230.1 2-oxoacid:acceptor oxidoreductase subunit alpha -
  ACH33_RS11985 (ACH33_11990) - 2436953..2437213 (-) 261 WP_057899231.1 stage V sporulation protein S -
  ACH33_RS11990 (ACH33_11995) - 2437331..2438128 (-) 798 WP_057899232.1 TIGR00282 family metallophosphoesterase -
  ACH33_RS11995 (ACH33_12000) rny 2438198..2439739 (-) 1542 WP_057899233.1 ribonuclease Y -
  ACH33_RS12000 (ACH33_12005) - 2439962..2440627 (-) 666 WP_082706038.1 RecX family transcriptional regulator -
  ACH33_RS12005 (ACH33_12010) recA 2440929..2441984 (-) 1056 WP_057899235.1 recombinase RecA Machinery gene
  ACH33_RS12010 (ACH33_12015) - 2442294..2442881 (+) 588 WP_057899236.1 biotin transporter BioY -
  ACH33_RS12015 (ACH33_12020) bioD 2442878..2443642 (+) 765 WP_057899237.1 dethiobiotin synthase -
  ACH33_RS12020 (ACH33_12025) bioA 2443684..2445042 (+) 1359 WP_057900362.1 adenosylmethionine--8-amino-7-oxononanoate transaminase -
  ACH33_RS12025 (ACH33_12030) - 2445160..2446740 (-) 1581 WP_057899238.1 DEAD/DEAH box helicase -
  ACH33_RS12030 (ACH33_12035) cinA 2446744..2447985 (-) 1242 WP_057899239.1 competence/damage-inducible protein A Machinery gene
  ACH33_RS12035 (ACH33_12040) pgsA 2448036..2448614 (-) 579 WP_057899240.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACH33_RS12040 (ACH33_12045) rimO 2448615..2449955 (-) 1341 WP_057899241.1 30S ribosomal protein S12 methylthiotransferase RimO -
  ACH33_RS12045 (ACH33_12050) - 2450059..2450907 (-) 849 WP_057899242.1 RodZ domain-containing protein -
  ACH33_RS12050 (ACH33_12055) - 2450939..2451739 (-) 801 WP_057899243.1 DUF3388 domain-containing protein -
  ACH33_RS12055 (ACH33_12060) - 2451902..2452156 (-) 255 WP_057899244.1 DUF3243 domain-containing protein -
  ACH33_RS12060 (ACH33_12065) fabG 2452255..2452992 (-) 738 WP_057899245.1 3-oxoacyl-ACP reductase FabG -
  ACH33_RS12065 (ACH33_12070) - 2453014..2454303 (-) 1290 WP_057899246.1 pitrilysin family protein -
  ACH33_RS12070 (ACH33_12075) - 2454304..2455587 (-) 1284 WP_057899247.1 pitrilysin family protein -
  ACH33_RS12075 (ACH33_12080) - 2455884..2456153 (-) 270 WP_057899248.1 hypothetical protein -
  ACH33_RS12080 (ACH33_12085) - 2456494..2456715 (-) 222 WP_057899249.1 hypothetical protein -
  ACH33_RS12085 (ACH33_12090) - 2456967..2457806 (+) 840 WP_082706040.1 serine/threonine-protein kinase -
  ACH33_RS12090 (ACH33_12095) - 2457822..2459621 (-) 1800 WP_082706041.1 ABC transporter ATP-binding protein -
  ACH33_RS12095 (ACH33_12100) - 2459865..2460743 (-) 879 WP_335338941.1 sulfurtransferase -
  ACH33_RS12100 (ACH33_12105) ppdK 2461034..2463700 (+) 2667 WP_057899251.1 pyruvate, phosphate dikinase -
  ACH33_RS19410 (ACH33_12115) - 2463847..2465024 (+) 1178 Protein_2487 IS3 family transposase -
  ACH33_RS12115 (ACH33_12120) - 2465104..2465511 (-) 408 WP_057899253.1 hypothetical protein -
  ACH33_RS12120 (ACH33_12125) - 2465610..2466353 (-) 744 WP_057899254.1 DnaD domain-containing protein -
  ACH33_RS12125 (ACH33_12130) - 2466674..2467204 (+) 531 WP_057899255.1 hypothetical protein -
  ACH33_RS12130 (ACH33_12135) - 2467293..2468471 (-) 1179 WP_057899256.1 pyridoxal phosphate-dependent aminotransferase -
  ACH33_RS12135 (ACH33_12140) - 2468718..2470247 (-) 1530 WP_057899257.1 AAA family ATPase -
  ACH33_RS12140 (ACH33_12145) - 2470240..2470671 (-) 432 WP_162265035.1 hypothetical protein -
  ACH33_RS12145 (ACH33_12150) - 2471043..2472221 (-) 1179 WP_057899259.1 RNA-guided endonuclease TnpB family protein -
  ACH33_RS12150 (ACH33_12155) - 2472350..2472838 (-) 489 WP_057899260.1 DUF5590 domain-containing protein -
  ACH33_RS12155 (ACH33_12160) - 2472976..2473161 (+) 186 WP_057899261.1 hypothetical protein -
  ACH33_RS12160 (ACH33_12165) - 2473250..2474551 (-) 1302 WP_057899262.1 amidohydrolase -
  ACH33_RS12165 (ACH33_12170) - 2474597..2475331 (-) 735 WP_327850987.1 redox-sensing transcriptional repressor Rex -
  ACH33_RS12170 (ACH33_12175) dinG 2475237..2478149 (-) 2913 WP_162265036.1 ATP-dependent DNA helicase DinG -
  ACH33_RS12175 (ACH33_12180) - 2478253..2479656 (-) 1404 WP_057899265.1 tetratricopeptide repeat protein -
  ACH33_RS12180 (ACH33_12185) panD 2480106..2480489 (-) 384 WP_057899266.1 aspartate 1-decarboxylase -
  ACH33_RS12185 (ACH33_12190) panC 2480474..2481343 (-) 870 WP_057899267.1 pantoate--beta-alanine ligase -
  ACH33_RS12190 (ACH33_12195) panB 2481340..2482194 (-) 855 WP_057899268.1 3-methyl-2-oxobutanoate hydroxymethyltransferase -
  ACH33_RS12195 (ACH33_12200) - 2482495..2483472 (-) 978 WP_057899269.1 biotin--[acetyl-CoA-carboxylase] ligase -
  ACH33_RS12200 (ACH33_12205) - 2483459..2484679 (-) 1221 WP_057899270.1 CCA tRNA nucleotidyltransferase -
  ACH33_RS12205 (ACH33_12210) bshA 2484676..2485818 (-) 1143 WP_057899271.1 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA -
  ACH33_RS12210 (ACH33_12215) bshB1 2485832..2486548 (-) 717 WP_057899272.1 bacillithiol biosynthesis deacetylase BshB1 -
  ACH33_RS12215 (ACH33_12220) - 2486545..2486964 (-) 420 WP_057899273.1 methylglyoxal synthase -
  ACH33_RS12220 (ACH33_12225) dapB 2486978..2487778 (-) 801 WP_057899274.1 4-hydroxy-tetrahydrodipicolinate reductase -
  ACH33_RS19415 - 2487775..2487942 (-) 168 WP_156424074.1 hypothetical protein -
  ACH33_RS12225 (ACH33_12230) - 2488097..2488441 (-) 345 WP_057899275.1 nucleotide pyrophosphohydrolase -
  ACH33_RS12230 (ACH33_12235) - 2488564..2489418 (+) 855 WP_057899276.1 YitT family protein -
  ACH33_RS12235 (ACH33_12240) - 2489570..2490415 (-) 846 WP_057899277.1 sporulation protein YpjB -
  ACH33_RS12240 (ACH33_12245) - 2490474..2491076 (-) 603 WP_057899278.1 DUF1405 domain-containing protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 44561.25 Da        Isoelectric Point: 6.9403

>NTDB_id=168656 ACH33_RS12030 WP_057899239.1 2446744..2447985(-) (cinA) [Aneurinibacillus sp. XH2]
MRAEIIAVGTELLLGQIANTNAQFLSQKLAEIGIGVYYHTVVGDNADRLYVQIQEALNRSDLLIFSGGLGPTKDDLTKET
VARAVGKPLVHDEQALARIIAYFKQRGMTMTENNRKQALVVEGSHVLPNDHGMAPGMVIEHKGKHLMMLPGPPRELHPMF
NTYGIPYLLSLMGGKNVVHSKVLRFFGIGESALEEELIDLIDSQTNPTIAPLAAEGEVTIRLTAKAKSVVEAETMIRSVE
EQIEARVGQFIYGYDDDSLASVLVRELSVRGETVAFAESVTGGLASHLLTSIPGSSAALKGSIICYTNEVKEKQLGVPRD
VLQTTGAVSGDAARIMAEQVRLRIGSTYGIAITGEAGPHASEKSIGLVYIGASDGKHTNVRELRLSGQRAAIQLRAAKHA
IFTMLERIKKGGF

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=168656 ACH33_RS12030 WP_057899239.1 2446744..2447985(-) (cinA) [Aneurinibacillus sp. XH2]
ATGAGAGCAGAAATTATTGCGGTCGGAACGGAGTTATTGCTTGGGCAAATCGCCAATACAAACGCCCAGTTCCTCTCGCA
AAAGTTAGCGGAAATTGGAATCGGTGTCTATTACCATACTGTCGTCGGCGACAATGCTGATCGGCTGTACGTACAGATTC
AAGAAGCGCTCAACCGTTCGGATTTGCTTATTTTTTCTGGAGGATTAGGGCCTACCAAAGATGACCTGACAAAAGAGACA
GTTGCCAGAGCTGTCGGGAAGCCATTGGTGCATGACGAACAGGCGCTTGCGCGCATTATCGCTTACTTTAAACAGCGCGG
CATGACGATGACGGAGAACAACCGTAAGCAGGCGCTTGTGGTGGAAGGAAGCCATGTATTGCCGAACGACCATGGCATGG
CACCGGGGATGGTTATTGAACATAAAGGTAAACATCTCATGATGCTACCAGGGCCTCCGCGTGAATTGCATCCGATGTTT
AACACGTATGGAATCCCCTACCTTTTGTCACTGATGGGTGGCAAAAACGTGGTGCACTCCAAAGTGCTTCGTTTTTTCGG
TATTGGTGAGTCGGCCCTTGAAGAAGAGTTGATAGATTTAATTGATTCTCAAACGAATCCGACGATTGCGCCGCTTGCGG
CTGAAGGGGAAGTCACGATTCGCTTGACCGCTAAAGCCAAAAGTGTGGTGGAAGCAGAGACGATGATCCGTTCCGTTGAA
GAACAAATCGAAGCGCGCGTCGGACAATTTATTTATGGATATGACGATGATTCGCTCGCTTCGGTGCTGGTGCGTGAGTT
AAGCGTACGTGGTGAAACGGTGGCATTTGCGGAGAGTGTGACAGGAGGTTTGGCGAGTCATTTACTCACTTCTATTCCGG
GCAGTTCGGCCGCGCTGAAAGGTTCTATCATTTGCTATACAAATGAAGTAAAGGAAAAGCAACTAGGCGTGCCGCGGGAT
GTGCTTCAGACCACGGGAGCGGTGAGTGGCGACGCAGCGCGTATTATGGCGGAGCAAGTGCGTCTTAGAATCGGAAGTAC
ATATGGAATTGCGATTACAGGAGAAGCTGGCCCACACGCGTCGGAGAAGTCTATAGGTCTCGTCTATATTGGCGCAAGCG
ATGGAAAACATACGAATGTCAGGGAACTTCGCCTATCCGGTCAGCGTGCCGCAATCCAGCTTCGTGCGGCAAAACATGCA
ATATTTACAATGCTTGAACGAATAAAAAAAGGTGGTTTTTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(257-406)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Bacillus subtilis subsp. subtilis str. 168

54.348

100

0.545
  cinA Streptococcus mitis NCTC 12261

46.602

99.758

0.465
  cinA Streptococcus mitis SK321

46.602

99.758

0.465
  cinA Streptococcus pneumoniae TIGR4

46.117

99.758

0.46
  cinA Streptococcus pneumoniae Rx1

45.631

99.758

0.455
  cinA Streptococcus pneumoniae R6

45.631

99.758

0.455
  cinA Streptococcus pneumoniae D39

45.388

99.758

0.453
  cinA Streptococcus mutans UA159

44.226

98.547

0.436
  cinA Streptococcus suis isolate S10

40.306

94.915

0.383

Multiple sequence alignment