Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   WH25_RS08325 Genome accession   NZ_CP017295
Coordinates   1736466..1737152 (-) Length   228 a.a.
NCBI ID   WP_008809440.1    Uniprot ID   A8AYC4
Organism   Streptococcus gordonii strain IE35     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1731466..1742152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS08300 (WH25_08300) - 1732251..1733018 (-) 768 WP_020992593.1 ABC transporter ATP-binding protein -
  WH25_RS08305 (WH25_08305) - 1733273..1734031 (-) 759 WP_046165330.1 TraX family protein -
  WH25_RS08310 (WH25_08310) - 1734229..1734873 (-) 645 WP_046165329.1 DUF6572 domain-containing protein -
  WH25_RS08315 (WH25_08315) - 1734899..1735456 (-) 558 WP_046165328.1 hypothetical protein -
  WH25_RS08320 (WH25_08320) - 1735502..1736482 (-) 981 WP_046165327.1 sensor histidine kinase -
  WH25_RS08325 (WH25_08325) braR 1736466..1737152 (-) 687 WP_008809440.1 response regulator transcription factor Regulator
  WH25_RS08330 (WH25_08330) - 1737362..1738621 (+) 1260 WP_046165326.1 NRAMP family divalent metal transporter -
  WH25_RS08335 (WH25_08335) - 1738746..1739930 (+) 1185 WP_046165325.1 DUF2974 domain-containing protein -
  WH25_RS08340 (WH25_08340) - 1740232..1741428 (+) 1197 WP_046165324.1 ferric reductase-like transmembrane domain-containing protein -
  WH25_RS08345 (WH25_08345) - 1741539..1742045 (-) 507 WP_046165323.1 DUF3592 domain-containing protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26494.78 Da        Isoelectric Point: 5.0042

>NTDB_id=168016 WH25_RS08325 WP_008809440.1 1736466..1737152(-) (braR) [Streptococcus gordonii strain IE35]
MHKIMLVEDDPVIRQMIKKMLEQWGYQVFAVEDFMEVLSLFVKEEPQLVLMDIGLPLFNGYHWCQEIRKISTVPIMFLSS
RDQAMDIVMAINMGGDDYVTKPFDNNVFLAKVQGLLRRSYEFGTDQNLLEHRGVILNLKSMDLMYNGQVITLTKNEFQIL
RVLFERAGSIVEREDLMKELWNSDFFIDDNTLSVNVARLRKKLEETGLKNFIETKKGIGYGLTNGHTE

Nucleotide


Download         Length: 687 bp        

>NTDB_id=168016 WH25_RS08325 WP_008809440.1 1736466..1737152(-) (braR) [Streptococcus gordonii strain IE35]
ATGCATAAGATTATGTTAGTAGAGGATGATCCAGTCATCCGTCAAATGATTAAAAAGATGTTGGAACAATGGGGTTATCA
AGTTTTTGCGGTTGAAGATTTTATGGAGGTTTTATCTCTTTTTGTTAAGGAGGAACCTCAGCTGGTCTTGATGGATATTG
GTCTGCCCCTCTTTAATGGCTATCATTGGTGCCAGGAGATTCGCAAGATTTCAACGGTTCCAATCATGTTTTTATCTTCA
CGAGATCAGGCTATGGATATCGTCATGGCTATCAATATGGGTGGTGATGACTACGTGACCAAGCCTTTTGACAATAATGT
CTTTCTGGCAAAGGTACAAGGATTGTTGCGCCGCTCTTATGAGTTTGGTACTGATCAAAATCTCCTAGAACACCGAGGCG
TGATTTTAAATCTCAAGTCTATGGACTTGATGTATAATGGTCAGGTCATTACGCTGACTAAGAATGAATTCCAGATTTTA
CGTGTTTTATTTGAGCGAGCAGGCAGTATAGTTGAGCGGGAAGATTTGATGAAAGAGCTATGGAATAGCGATTTCTTTAT
TGATGATAATACCCTATCTGTCAATGTTGCTAGGCTCCGGAAAAAACTGGAAGAAACAGGTCTTAAGAACTTTATTGAGA
CGAAAAAAGGGATTGGATACGGTCTGACAAATGGACACACAGAATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8AYC4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

49.541

95.614

0.474

Multiple sequence alignment