Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   AV941_RS14955 Genome accession   NZ_CP013930
Coordinates   3375913..3377121 (+) Length   402 a.a.
NCBI ID   WP_015067812.1    Uniprot ID   A0AAC8XLD7
Organism   Alteromonas mediterranea strain U10     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3370913..3382121
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AV941_RS14930 (AV941_14880) ampE 3371870..3372739 (-) 870 WP_015067808.1 beta-lactamase regulator AmpE -
  AV941_RS14935 (AV941_14885) ampD 3372770..3373306 (-) 537 WP_015067809.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  AV941_RS14940 (AV941_14890) - 3373482..3374000 (+) 519 WP_012519426.1 retropepsin-like aspartic protease family protein -
  AV941_RS14945 (AV941_14895) nadC 3374020..3374874 (+) 855 WP_015067810.1 carboxylating nicotinate-nucleotide diphosphorylase -
  AV941_RS14950 (AV941_14900) - 3375410..3375838 (+) 429 WP_015067811.1 pilin -
  AV941_RS14955 (AV941_14905) pilC 3375913..3377121 (+) 1209 WP_015067812.1 type II secretion system F family protein Machinery gene
  AV941_RS14960 (AV941_14910) pilD 3377251..3378144 (+) 894 WP_015067813.1 prepilin peptidase Machinery gene
  AV941_RS14965 (AV941_14915) coaE 3378166..3378780 (+) 615 WP_015067814.1 dephospho-CoA kinase -
  AV941_RS14970 (AV941_14920) zapD 3378993..3379745 (+) 753 WP_015067815.1 cell division protein ZapD -
  AV941_RS14975 (AV941_14925) yacG 3379836..3380063 (+) 228 WP_012519434.1 DNA gyrase inhibitor YacG -
  AV941_RS14980 (AV941_14930) - 3380256..3381128 (+) 873 WP_015067816.1 aspartoacylase -
  AV941_RS14985 (AV941_14935) mutT 3381220..3381603 (-) 384 WP_015067817.1 8-oxo-dGTP diphosphatase MutT -

Sequence

Protein


Download         Length: 402 a.a.        Molecular weight: 43611.36 Da        Isoelectric Point: 9.5990

>NTDB_id=166231 AV941_RS14955 WP_015067812.1 3375913..3377121(+) (pilC) [Alteromonas mediterranea strain U10]
MAKAAITFIWQGKDRRGQSRKGEISATSLSEAKNLLRRQGISANKVKKLATPLFGGAKKITPADISVISRQIATMLAAGV
TLIQSLEMIAQGHANPSMRKLLGEITEEVKSGNPLSSALRKHPLYFDDLYCDLVYTGEQSGALETIYDRIATYKEKAEAL
KSKIKKAMFYPIAVLVVAFIVTTILLIFVVPQFEEIFSSFGAELPAFTVFVLGISRFVQDYGIFIAMGVAAAGFMFVRAH
RRSQKLRDTVDRNILKIPVIGEILKKASIARFTRTLATTFAAGVPLIGALESAAGASGNAVYRDAILYIRKEVAGGMPMH
VAMRATQVFPDMVTQMIAIGEESGAVDEMLSKIATIYEAEVDDMVDGLTSLLEPMIMAVLGVVIGGLIVAMYLPIFEMGN
VV

Nucleotide


Download         Length: 1209 bp        

>NTDB_id=166231 AV941_RS14955 WP_015067812.1 3375913..3377121(+) (pilC) [Alteromonas mediterranea strain U10]
ATGGCAAAAGCTGCAATAACTTTCATATGGCAAGGAAAAGACCGTCGAGGGCAGTCTCGTAAAGGCGAAATTTCTGCCAC
ATCCTTATCTGAAGCAAAAAATCTTCTACGCCGTCAAGGTATATCTGCTAACAAAGTCAAGAAACTTGCAACGCCCTTAT
TTGGCGGCGCGAAGAAAATTACGCCAGCAGATATCTCGGTAATATCTCGTCAAATAGCTACCATGCTTGCCGCAGGTGTT
ACGCTTATCCAATCTTTAGAAATGATAGCGCAGGGCCATGCGAACCCTTCCATGCGTAAACTGCTTGGTGAAATCACCGA
AGAAGTAAAGTCGGGTAATCCTCTTTCTTCAGCGCTTAGAAAACACCCTCTTTATTTTGACGACCTGTATTGTGATTTGG
TTTACACGGGCGAACAATCGGGTGCCCTTGAAACTATTTACGACCGTATTGCCACCTATAAAGAAAAGGCTGAAGCACTA
AAATCAAAAATCAAAAAAGCGATGTTTTACCCTATCGCGGTTTTGGTTGTTGCTTTTATCGTTACGACTATTCTGCTTAT
ATTCGTTGTACCTCAGTTTGAAGAAATCTTTAGTAGTTTTGGCGCAGAACTTCCTGCCTTTACTGTATTTGTATTGGGAA
TTTCGCGATTTGTGCAAGACTACGGTATTTTTATCGCCATGGGCGTGGCAGCCGCAGGCTTTATGTTTGTGCGTGCACAC
AGACGTAGCCAAAAACTGCGCGATACGGTAGACCGTAATATATTAAAAATACCTGTTATCGGTGAGATACTTAAAAAAGC
CAGTATCGCCCGCTTTACCCGTACCCTTGCCACCACCTTTGCGGCAGGTGTTCCGCTAATAGGCGCGTTAGAGTCGGCAG
CGGGGGCATCCGGTAACGCGGTTTATCGCGATGCCATTTTATATATACGAAAAGAAGTGGCCGGTGGTATGCCTATGCAT
GTAGCCATGCGCGCAACCCAAGTATTTCCTGACATGGTGACGCAAATGATAGCCATAGGTGAAGAGTCTGGCGCGGTAGA
TGAAATGCTAAGTAAAATTGCCACCATTTACGAAGCAGAAGTTGATGACATGGTAGACGGCTTAACCAGCTTGCTTGAGC
CTATGATCATGGCTGTACTTGGTGTGGTTATCGGCGGCTTGATTGTGGCCATGTACCTGCCTATATTCGAAATGGGTAAC
GTGGTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(69-191)

Type II secretion system (T2SS), protein F (T2SSF)

(272-394)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

59.012

100

0.595
  pilC Legionella pneumophila strain ERS1305867

53.25

99.502

0.53
  pilC Acinetobacter baumannii D1279779

52.764

99.005

0.522
  pilC Acinetobacter baylyi ADP1

52.393

98.756

0.517
  pilG Neisseria gonorrhoeae MS11

45.567

100

0.46
  pilG Neisseria meningitidis 44/76-A

44.802

100

0.45
  pilC Vibrio cholerae strain A1552

45.088

98.756

0.445
  pilC Vibrio campbellii strain DS40M4

42.821

98.756

0.423
  pilC Thermus thermophilus HB27

36.5

99.502

0.363

Multiple sequence alignment