Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   A7J08_RS06070 Genome accession   NZ_CP017088
Coordinates   1214322..1214981 (-) Length   219 a.a.
NCBI ID   WP_148115779.1    Uniprot ID   -
Organism   Streptococcus suis strain SRD478     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1209322..1219981
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS06055 (A7J08_05890) - 1210199..1211026 (-) 828 WP_053867324.1 hypothetical protein -
  A7J08_RS06060 (A7J08_05895) - 1211120..1211776 (-) 657 WP_053867325.1 CBS domain-containing protein -
  A7J08_RS10420 (A7J08_05900) - 1211959..1212084 (-) 126 Protein_1125 IS982 family transposase -
  A7J08_RS06065 (A7J08_05905) comEC/celB 1212101..1214338 (-) 2238 WP_148115778.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  A7J08_RS06070 (A7J08_05910) comEA/celA/cilE 1214322..1214981 (-) 660 WP_148115779.1 helix-hairpin-helix domain-containing protein Machinery gene
  A7J08_RS06075 (A7J08_05915) - 1215049..1215795 (-) 747 WP_053866958.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  A7J08_RS06080 (A7J08_05920) - 1215943..1217388 (+) 1446 WP_024382741.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  A7J08_RS06085 (A7J08_05925) - 1217541..1218326 (+) 786 WP_044758826.1 ABC transporter ATP-binding protein -
  A7J08_RS06090 (A7J08_05930) - 1218339..1219268 (+) 930 WP_053866959.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23230.82 Da        Isoelectric Point: 4.1214

>NTDB_id=166037 A7J08_RS06070 WP_148115779.1 1214322..1214981(-) (comEA/celA/cilE) [Streptococcus suis strain SRD478]
MDTIKTYIEMLKEYKWQIALPAVAGLLMATFLIFSQPAKSDQTGLTDFSQTAQTSSSQEQTEEINTEASEEPSQLVIDVK
GAVEKPGLYTLEAGARVNDAVEAAGGLTSQANPKSINLAQKLSDEAVVYVASKDENISVVTSTTASSAMSPEGNEGKVNL
NTATEADLQTISGIGAKRATDIIAYREANGGFKSVDDLNNVSGIGDKTIESIRPYVTVE

Nucleotide


Download         Length: 660 bp        

>NTDB_id=166037 A7J08_RS06070 WP_148115779.1 1214322..1214981(-) (comEA/celA/cilE) [Streptococcus suis strain SRD478]
ATGGATACGATTAAAACCTATATAGAAATGCTTAAAGAATACAAGTGGCAGATTGCCTTGCCCGCAGTAGCTGGCTTGCT
AATGGCGACGTTCTTAATATTCAGCCAACCAGCCAAGTCTGATCAGACAGGCCTGACAGATTTTTCCCAGACTGCACAAA
CTTCTAGCAGTCAGGAGCAGACGGAGGAAATCAATACAGAAGCAAGTGAGGAACCCAGCCAGCTGGTCATTGATGTCAAA
GGAGCGGTGGAAAAACCAGGGCTCTACACCTTAGAAGCTGGTGCGCGTGTCAATGACGCAGTTGAGGCAGCTGGTGGCTT
GACCAGTCAGGCAAATCCCAAATCTATCAATCTGGCTCAGAAGCTCAGCGATGAGGCGGTGGTCTATGTGGCCAGCAAGG
ACGAAAATATCTCGGTGGTGACTAGCACGACTGCCAGCTCTGCTATGTCCCCAGAAGGAAATGAAGGTAAGGTCAATCTC
AATACGGCGACCGAGGCGGACCTGCAGACCATTTCTGGTATTGGTGCCAAGCGAGCGACAGACATTATCGCCTATCGTGA
GGCAAACGGTGGCTTCAAGTCGGTGGATGACCTCAACAATGTGTCGGGTATCGGCGACAAGACCATAGAAAGCATCCGGC
CTTATGTTACGGTTGAGTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_3)

(154-217)

SLBB domain (SLBB)

(76-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

47.032

100

0.47
  comEA/celA/cilE Streptococcus pneumoniae D39

47.032

100

0.47
  comEA/celA/cilE Streptococcus pneumoniae R6

47.032

100

0.47
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

47.685

98.63

0.47
  comEA/celA/cilE Streptococcus mitis NCTC 12261

46.759

98.63

0.461
  comEA/celA/cilE Streptococcus mitis SK321

45.455

100

0.457
  comEA Streptococcus thermophilus LMD-9

59.748

72.603

0.434
  comEA Bacillus subtilis subsp. subtilis str. 168

38.756

95.434

0.37
  comEA Lactococcus lactis subsp. cremoris KW2

36.486

100

0.37