Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   AV644_RS10320 Genome accession   NZ_CP013908
Coordinates   1992834..1994093 (-) Length   419 a.a.
NCBI ID   WP_001200981.1    Uniprot ID   A0AAD3A4E0
Organism   Streptococcus agalactiae strain GBS-M002     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1987834..1999093
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AV644_RS10285 (AV644_09950) - 1987985..1989526 (-) 1542 WP_000230047.1 hypothetical protein -
  AV644_RS11300 (AV644_09955) - 1989572..1989694 (-) 123 WP_001285711.1 hypothetical protein -
  AV644_RS10295 (AV644_09960) - 1989777..1990094 (-) 318 WP_000940932.1 DUF1292 domain-containing protein -
  AV644_RS10300 (AV644_09965) ruvX 1990120..1990539 (-) 420 WP_001222109.1 Holliday junction resolvase RuvX -
  AV644_RS10305 (AV644_09970) - 1990539..1990805 (-) 267 WP_000507056.1 IreB family regulatory phosphoprotein -
  AV644_RS10310 (AV644_09975) spx 1991007..1991405 (-) 399 WP_000591161.1 transcriptional regulator Spx -
  AV644_RS10315 (AV644_09980) recA 1991621..1992760 (-) 1140 WP_001085741.1 recombinase RecA Machinery gene
  AV644_RS10320 (AV644_09985) cinA 1992834..1994093 (-) 1260 WP_001200981.1 competence/damage-inducible protein A Machinery gene
  AV644_RS10325 (AV644_09990) - 1994182..1994733 (-) 552 WP_000817341.1 DNA-3-methyladenine glycosylase I -
  AV644_RS10330 (AV644_09995) ruvA 1994756..1995346 (-) 591 WP_000272490.1 Holliday junction branch migration protein RuvA -
  AV644_RS10335 (AV644_10000) - 1995348..1996580 (-) 1233 WP_000657483.1 MDR family MFS transporter -
  AV644_RS10340 (AV644_10005) mutL 1996612..1998585 (-) 1974 WP_000034613.1 DNA mismatch repair endonuclease MutL -
  AV644_RS10350 (AV644_10010) - 1998811..1999014 (+) 204 WP_000191849.1 cold-shock protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45444.26 Da        Isoelectric Point: 5.8937

>NTDB_id=165955 AV644_RS10320 WP_001200981.1 1992834..1994093(-) (cinA) [Streptococcus agalactiae strain GBS-M002]
MRAEIIAVGTEILTGQIVNTNAQFLSEKMAELGIDIYFQTAVGDNEERLLSLLDIASQRSQMVILCGGLGPTEDDLTKQT
LAKFLGKSLTVDLLASQKLDRFFASRPQFARTPNNERQAQLVEGSIPLQNLTGLAVGGIVTSKGVQYMVLPGPPSELKPM
VMEQAVPILSNNGTKLYSRVLRFFGIGESQLVTILEDIIKNQTDPTIAPYAKVGEVTLRLSTKAENQDEADFKLDSLEKE
ILALKTLDNRKLKDLLYGYGDNNSMARTVLELLKVQNKTITAAESLTAGLFQSQLAEFSGASQVFNGGFTTYSMEAKSQL
LGIPKKKLQEYGVVSHFTAEAMAQQARQLLKADFGIGLTGVAGPDELEGYPAGTVFIGIATPEGVSSIKVSIGGKSRSDV
RHISTLHAFDLVRRALLKI

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=165955 AV644_RS10320 WP_001200981.1 1992834..1994093(-) (cinA) [Streptococcus agalactiae strain GBS-M002]
GTGAGGGCTGAAATTATCGCTGTAGGAACAGAAATTTTAACAGGACAGATCGTTAATACAAACGCACAATTTTTGTCGGA
GAAAATGGCAGAATTGGGAATTGATATTTATTTCCAGACAGCTGTAGGAGATAATGAGGAACGTTTATTATCGCTTTTAG
ATATAGCTAGTCAGCGCAGTCAAATGGTTATCCTATGTGGTGGACTTGGACCTACAGAGGATGATTTAACGAAACAAACT
TTGGCTAAATTTTTAGGTAAATCATTAACAGTGGATTTATTAGCTAGTCAAAAATTGGATCGTTTTTTTGCAAGTCGTCC
TCAGTTTGCTAGAACACCAAATAATGAACGACAAGCTCAATTGGTTGAAGGCTCAATACCTCTACAAAACCTTACTGGTC
TAGCTGTTGGTGGTATCGTTACATCTAAGGGAGTCCAATATATGGTTTTACCAGGTCCGCCTAGTGAATTAAAGCCAATG
GTTATGGAGCAGGCGGTACCTATTTTGTCAAATAATGGCACAAAATTATATTCACGTGTATTGAGATTCTTTGGTATTGG
TGAGAGTCAGTTAGTCACAATCTTAGAAGACATAATTAAGAATCAGACAGATCCAACTATAGCACCATATGCAAAGGTTG
GTGAGGTAACTTTAAGGTTATCAACGAAAGCTGAAAATCAGGATGAGGCCGACTTTAAATTAGATAGCTTAGAAAAAGAA
ATACTTGCTCTTAAGACATTAGATAACCGTAAATTAAAAGATTTATTATATGGTTATGGTGATAATAATAGTATGGCACG
TACTGTTTTAGAATTATTGAAAGTACAAAATAAAACGATTACTGCCGCAGAGAGCTTAACAGCAGGGTTATTTCAATCTC
AGTTAGCAGAATTTTCTGGTGCTTCGCAAGTTTTTAATGGTGGTTTTACGACCTATAGTATGGAAGCAAAATCACAACTT
CTCGGCATCCCTAAGAAAAAATTGCAAGAATATGGAGTTGTCAGTCATTTTACAGCTGAGGCAATGGCTCAGCAAGCTCG
CCAACTTTTAAAAGCAGATTTTGGTATCGGTTTAACGGGAGTTGCTGGTCCTGATGAGTTGGAAGGATACCCTGCAGGTA
CAGTTTTTATTGGGATTGCAACCCCTGAAGGCGTTTCTTCTATTAAAGTATCGATTGGAGGGAAGAGCCGCTCAGATGTC
CGTCATATCAGTACTTTACATGCTTTTGACCTGGTGCGTAGGGCTTTATTAAAGATATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

71.463

99.523

0.711
  cinA Streptococcus mitis NCTC 12261

71.223

99.523

0.709
  cinA Streptococcus pneumoniae TIGR4

70.024

99.523

0.697
  cinA Streptococcus pneumoniae Rx1

70.024

99.523

0.697
  cinA Streptococcus pneumoniae R6

70.024

99.523

0.697
  cinA Streptococcus pneumoniae D39

69.784

99.523

0.695
  cinA Streptococcus mutans UA159

68.106

99.523

0.678
  cinA Streptococcus suis isolate S10

55.048

99.284

0.547
  cinA Bacillus subtilis subsp. subtilis str. 168

44.019

99.761

0.439

Multiple sequence alignment