Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   AU077_RS09175 Genome accession   NZ_CP013688
Coordinates   1844487..1845386 (-) Length   299 a.a.
NCBI ID   WP_058621959.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain ICDDRB-NRC-S1     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1839487..1850386
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AU077_RS09150 (AU077_09150) - 1840503..1840726 (-) 224 Protein_1859 phosphoribosylaminoimidazole carboxylase -
  AU077_RS09155 (AU077_09155) purK 1840746..1841837 (-) 1092 WP_058621956.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  AU077_RS09160 (AU077_09160) purE 1841824..1842312 (-) 489 WP_014293778.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  AU077_RS09165 (AU077_09165) - 1842312..1842761 (-) 450 WP_058621957.1 DUF523 domain-containing protein -
  AU077_RS09170 (AU077_09170) purD 1842751..1844013 (-) 1263 WP_058621958.1 phosphoribosylamine--glycine ligase -
  AU077_RS09175 (AU077_09175) comR 1844487..1845386 (-) 900 WP_058621959.1 helix-turn-helix domain-containing protein Regulator
  AU077_RS09180 (AU077_09180) - 1845565..1846200 (-) 636 WP_014293774.1 CPBP family intramembrane glutamic endopeptidase -
  AU077_RS09185 (AU077_09185) - 1846212..1846664 (-) 453 WP_058621960.1 hypothetical protein -
  AU077_RS09190 (AU077_09190) - 1846677..1846886 (-) 210 WP_014293772.1 hypothetical protein -
  AU077_RS09195 (AU077_09195) - 1846896..1847096 (-) 201 WP_012961332.1 helix-turn-helix transcriptional regulator -
  AU077_RS09200 (AU077_09200) - 1847258..1848457 (-) 1200 WP_014293771.1 acetate kinase -
  AU077_RS09205 (AU077_09205) comYH 1848510..1849466 (-) 957 WP_014293770.1 class I SAM-dependent methyltransferase Machinery gene
  AU077_RS09210 (AU077_09210) comYG 1849548..1849853 (-) 306 WP_058621961.1 competence type IV pilus minor pilin ComGG Machinery gene
  AU077_RS09215 (AU077_09215) comYF 1849825..1850292 (-) 468 WP_014293768.1 competence type IV pilus minor pilin ComGF Machinery gene

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35018.18 Da        Isoelectric Point: 4.9629

>NTDB_id=164071 AU077_RS09175 WP_058621959.1 1844487..1845386(-) (comR) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
MEKFGIKVRALREEKGISREEFCGDETELSVRQLVRIEKGQSVPTLNKVGYIAKVLDVTIGELVDGKNLELPTRYKELKY
LLLRTPTYGDEKRLQRQTSYFDEIAERYYEVIPEEERLVIDCLQSKIDVHFSDDVNFGEGILNDYFDQVRRKKKFQINDL
ILIDLYFACLASAKSFEGIYSLDLYDELMECLLNQENLSPETSLILNNVLLNNVDLVLRFHRESFIKRIIIKSDTIMASI
HDFQRRPVLSLVEWKYYLQFKKDFLAAQKSYSNAILFANLIGDTYLKSKLVEEWNNDTT

Nucleotide


Download         Length: 900 bp        

>NTDB_id=164071 AU077_RS09175 WP_058621959.1 1844487..1845386(-) (comR) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
TTGGAAAAGTTTGGAATTAAAGTACGTGCATTAAGAGAGGAAAAAGGAATTTCACGTGAGGAATTTTGTGGCGATGAAAC
AGAATTGTCTGTACGGCAATTAGTTAGAATTGAAAAGGGACAATCCGTTCCAACTCTTAATAAAGTGGGATATATTGCAA
AGGTTTTGGACGTAACGATTGGTGAATTAGTTGATGGTAAAAATCTAGAGCTTCCTACTAGATACAAGGAGTTAAAGTAT
TTATTATTGCGAACACCGACTTATGGAGATGAGAAACGTCTTCAGAGACAAACTTCCTATTTTGACGAGATTGCAGAAAG
ATATTACGAAGTTATACCTGAAGAGGAACGTTTGGTTATTGATTGTTTACAATCAAAGATTGATGTTCATTTCAGTGATG
ATGTTAATTTTGGTGAGGGAATTTTAAATGACTATTTTGACCAGGTTAGACGAAAGAAAAAATTTCAAATCAATGATTTG
ATTTTAATAGATTTATATTTTGCTTGCCTTGCTTCTGCTAAATCGTTTGAGGGAATCTATAGCTTAGATTTATATGATGA
ATTAATGGAGTGTTTGCTGAATCAAGAAAATCTTTCGCCAGAAACTTCTTTGATTTTAAATAATGTTTTATTAAATAATG
TAGATTTGGTTTTACGATTCCATAGAGAATCATTTATAAAACGAATAATTATAAAAAGCGACACTATCATGGCAAGTATT
CATGATTTTCAAAGACGTCCAGTTTTAAGTTTAGTTGAGTGGAAATATTATTTACAATTTAAAAAAGATTTTTTAGCGGC
ACAAAAATCTTACTCCAATGCAATTTTATTTGCTAATTTAATTGGAGATACTTATTTGAAAAGTAAATTAGTAGAAGAAT
GGAATAATGATACAACATGA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(8-63)

ComR tetratricopeptide (ComR_TPR)

(72-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

71.777

95.987

0.689
  comR Streptococcus mutans UA159

53.512

100

0.535
  comR Streptococcus pyogenes MGAS8232

48.667

100

0.488
  comR Streptococcus pyogenes MGAS315

47.651

99.666

0.475
  comR Streptococcus suis P1/7

39.933

99.666

0.398
  comR Streptococcus suis 05ZYH33

40.067

99.331

0.398
  comR Streptococcus suis D9

38.591

99.666

0.385

Multiple sequence alignment