Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   HSISS4_RS00340 Genome accession   NZ_CP013216
Coordinates   60534..61802 (+) Length   422 a.a.
NCBI ID   WP_002886326.1    Uniprot ID   A0AB35IYG6
Organism   Streptococcus salivarius strain HSISS4     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 55534..66802
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSISS4_RS00310 (HSISS4_00041) - 55864..56301 (-) 438 WP_059749062.1 LytTR family DNA-binding domain-containing protein -
  HSISS4_RS00315 (HSISS4_00042) - 56480..56785 (+) 306 WP_042762228.1 hypothetical protein -
  HSISS4_RS00320 (HSISS4_00043) mutL 56837..58774 (+) 1938 WP_021143432.1 DNA mismatch repair endonuclease MutL -
  HSISS4_RS00325 (HSISS4_00044) - 58905..59126 (+) 222 WP_002886321.1 hypothetical protein -
  HSISS4_RS00330 (HSISS4_00045) ruvA 59284..59874 (+) 591 WP_002886323.1 Holliday junction branch migration protein RuvA -
  HSISS4_RS00335 (HSISS4_00046) - 59883..60437 (+) 555 WP_002886325.1 DNA-3-methyladenine glycosylase I -
  HSISS4_RS00340 (HSISS4_00047) cinA 60534..61802 (+) 1269 WP_002886326.1 competence/damage-inducible protein A Machinery gene
  HSISS4_RS00345 (HSISS4_00048) recA 61838..62977 (+) 1140 WP_002886327.1 recombinase RecA Machinery gene
  HSISS4_RS00350 (HSISS4_00049) spx 63144..63542 (+) 399 WP_002886328.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45683.85 Da        Isoelectric Point: 5.1868

>NTDB_id=160682 HSISS4_RS00340 WP_002886326.1 60534..61802(+) (cinA) [Streptococcus salivarius strain HSISS4]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNESRLLSVLDQASQRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELVFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAIPLQNPTGLAVGGIITAQGVTYVVLPGPPSELKPM
VNQELIPALTENHSSLYSRVLRFFGVGESQLVTVLKDFIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADQKLDVLEKQ
IRSTKTLDGKSLSDFIYGYGESNSLAFEAFRLLKHHGKTITAAESLTAGLFQASIADFSGASQVFKGGFVTYSIEEKAKM
LDIPLSQLEEHGVVSHFTAEKMAEGARAKTDSDYGVALTGVAGPDSLEGHPAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RYISTLYAFNLVRQALLQEDMI

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=160682 HSISS4_RS00340 WP_002886326.1 60534..61802(+) (cinA) [Streptococcus salivarius strain HSISS4]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATCCTAACCGGGCAGATCACCAATACCAATGCCCAATTTTTATCTGA
GAAACTAGCTGAACTAGGAATTGACGTGTATTTTCACACAGCAGTAGGAGACAATGAAAGCCGCCTACTTTCAGTTCTTG
ATCAAGCCAGTCAGCGTAGTGATTTAGTCATACTTTGTGGTGGACTTGGCCCTACTGAGGACGACCTAACCAAGCAAACC
CTGGCTAAATTTTTAGGAAAAGAACTCGTTTTTGATGAGGAGGCTAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACACACACGAACGCCTAATAATGAACGTCAAGCACAAATTGTTGAGGGGGCTATTCCCTTGCAAAACCCGACAGGTC
TTGCAGTTGGAGGGATTATTACTGCTCAAGGGGTGACCTATGTAGTCTTACCTGGTCCACCAAGTGAACTCAAACCTATG
GTGAATCAAGAACTTATTCCAGCTCTTACTGAGAATCACTCAAGTCTTTATTCGAGAGTCCTAAGATTCTTCGGCGTTGG
AGAAAGTCAATTAGTGACTGTTCTTAAGGATTTTATTGTTAACCAAACAGATCCAACCATAGCTCCATACGCTAAAGTGG
GGGAAGTAACACTTCGCTTGTCAACGAAGGCTTCTTCGCAAGAAGAAGCAGATCAAAAACTAGATGTTTTAGAAAAACAA
ATTCGTTCGACTAAAACTCTAGATGGCAAATCCTTATCTGATTTCATTTATGGATATGGAGAGTCTAATAGTTTAGCCTT
TGAAGCTTTTCGTTTGCTTAAGCACCATGGCAAGACCATCACTGCAGCTGAAAGCCTAACAGCAGGTTTATTTCAGGCTA
GTATTGCTGATTTTTCAGGGGCCTCACAAGTATTTAAAGGTGGATTTGTTACTTATAGTATTGAAGAAAAAGCTAAAATG
TTGGATATTCCCTTGTCGCAACTAGAAGAACATGGTGTTGTCAGTCATTTTACTGCAGAAAAAATGGCTGAAGGTGCTCG
AGCTAAAACAGATAGCGATTATGGAGTTGCACTTACCGGTGTAGCTGGACCAGATTCATTAGAAGGACACCCAGCAGGTA
CGGTATTTATTGGTATTGCTGATAGGAATCAAGTAAGGTCGATCAAGGTTGTTATAGGTGGAAGAAGTCGTTCTGATGTT
AGATATATTAGTACCCTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAAGACATGATTTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(264-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

75.179

99.289

0.746
  cinA Streptococcus mitis NCTC 12261

74.702

99.289

0.742
  cinA Streptococcus pneumoniae TIGR4

73.747

99.289

0.732
  cinA Streptococcus pneumoniae Rx1

73.508

99.289

0.73
  cinA Streptococcus pneumoniae R6

73.508

99.289

0.73
  cinA Streptococcus pneumoniae D39

73.27

99.289

0.727
  cinA Streptococcus mutans UA159

71.703

98.815

0.709
  cinA Streptococcus suis isolate S10

55.529

98.578

0.547
  cinA Bacillus subtilis subsp. subtilis str. 168

44.893

99.763

0.448

Multiple sequence alignment