Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   AMR85_RS06645 Genome accession   NZ_CP012522
Coordinates   1339529..1340770 (-) Length   413 a.a.
NCBI ID   WP_044145070.1    Uniprot ID   A0A3F3LN87
Organism   Enterococcus faecium strain 64/3 isolate human patient     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1334529..1345770
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AMR85_RS06630 (AMR85_06610) proC 1335519..1336325 (+) 807 WP_002296027.1 pyrroline-5-carboxylate reductase -
  AMR85_RS06635 (AMR85_06615) rny 1336404..1337960 (-) 1557 WP_002287336.1 ribonuclease Y -
  AMR85_RS06640 (AMR85_06620) recA 1338371..1339420 (-) 1050 WP_002287328.1 recombinase RecA Machinery gene
  AMR85_RS06645 (AMR85_06625) cinA 1339529..1340770 (-) 1242 WP_044145070.1 competence/damage-inducible protein A Machinery gene
  AMR85_RS06650 (AMR85_06630) pgsA 1341010..1341588 (-) 579 WP_002296025.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AMR85_RS06655 (AMR85_06635) - 1341797..1342720 (-) 924 WP_002287423.1 RodZ domain-containing protein -
  AMR85_RS06660 (AMR85_06640) yfmH 1343334..1344620 (-) 1287 WP_002287425.1 EF-P 5-aminopentanol modification-associated protein YfmH -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45445.85 Da        Isoelectric Point: 4.6507

>NTDB_id=154971 AMR85_RS06645 WP_044145070.1 1339529..1340770(-) (cinA) [Enterococcus faecium strain 64/3 isolate human patient]
MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGDNQQRLEELIALAETRSELILLCGGLGPTEDDLTKEA
TAAHLGKSLIQNTEGYKKLLAYFETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTNDVQAGNQALLALE
EKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVTAAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDP
ELLAEYGTVSKECVEQMAIQAREIARTDYSVAFTGVAGPDMLEGQSAGTVWIAISSKDGVVSEKYHFARDRAAIRYNAVM
QGFDLLRKQLLRK

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=154971 AMR85_RS06645 WP_044145070.1 1339529..1340770(-) (cinA) [Enterococcus faecium strain 64/3 isolate human patient]
ATGAAAGCAGAAATAATAGCTGTCGGAACAGAACTTTTACTAGGACAAGTCGTGAATACGAATGCCACTTTCTTGTCAGA
ACAGCTAGCTGATCTAGGTATCGAAGTTTATTATCAAACAGTTGTAGGAGATAATCAGCAGCGTTTAGAAGAGTTGATTG
CTCTAGCTGAAACAAGAAGTGAACTCATACTCTTATGTGGCGGATTAGGACCGACAGAAGATGACCTGACAAAAGAAGCA
ACTGCGGCTCACCTCGGTAAGTCTCTCATACAAAATACGGAAGGATACAAAAAATTATTGGCATATTTTGAAACAACCCA
TCGAAAAATGACCAAAAACAATCTGCAACAGTCCCAGATTATCGAAGGCGGGGTTCCTCTACCAAATCGTACAGGGCTTG
CTTTAGGGACTTTTTATCAAACAGATACACATGCGTATATCCTTCTTCCCGGTCCGCCTAATGAGTTGAAACCAATGTTT
GTGGAACAAGTACGTCCTTTACTAGAGGAACGTTTTCCTTCTGAAGAAAAACTAATTTCTAAAGTTTTGCGCTTTTATGG
GATTGGTGAATCGCGACTGGTCACTGAGCTAAAAGATCTGATTGAGACACAGATCAATCCAACGATCGCACCATATGCCA
AACCAAATGAAGTGACATTACGACTGACAGTGAAAACAAATGATGTTCAGGCAGGGAATCAAGCTCTTTTAGCATTAGAA
GAAAAAATCCAAGAACGAGTAGGGGAATATTTTTATGGATACGGCGATGATAATTCGCTAGCAAAAGTCGTAGTGGAACT
ACTGAAAGAAAACAAGCAGACTGTAACAGCAGCGGAAAGTTTGACAGCCGGCGCCTTCCAAGCCGCATTAGGCGACATTG
CTGGTGTATCTGAAGTATTTCCAGGCGGATTCGTTACCTACTCGCTCCAAACAAAAGCTGGTTTTCTGGAGATTGATCCG
GAGCTATTAGCAGAATATGGAACAGTCAGCAAAGAATGTGTGGAGCAGATGGCCATTCAAGCACGTGAGATAGCAAGAAC
AGATTACAGTGTAGCTTTCACCGGAGTGGCTGGACCGGACATGTTAGAAGGTCAATCTGCAGGAACAGTATGGATCGCTA
TTTCATCTAAAGACGGCGTGGTTTCGGAAAAATATCACTTTGCCAGAGATCGTGCTGCTATCAGATATAATGCGGTTATG
CAAGGATTTGATCTTTTGAGAAAACAGCTTTTAAGAAAATGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(258-410)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3F3LN87

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

51.19

100

0.521
  cinA Streptococcus mutans UA159

51.566

100

0.518
  cinA Streptococcus pneumoniae TIGR4

50.952

100

0.518
  cinA Streptococcus pneumoniae D39

50.714

100

0.516
  cinA Streptococcus pneumoniae R6

50.714

100

0.516
  cinA Streptococcus pneumoniae Rx1

50.714

100

0.516
  cinA Streptococcus mitis NCTC 12261

50.714

100

0.516
  cinA Bacillus subtilis subsp. subtilis str. 168

47.573

99.758

0.475
  cinA Streptococcus suis isolate S10

41.787

100

0.419

Multiple sequence alignment