Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   UP12_RS16135 Genome accession   NZ_CP011007
Coordinates   3172928..3173524 (+) Length   198 a.a.
NCBI ID   WP_024719872.1    Uniprot ID   A0A2G8ISB7
Organism   Bacillus pumilus strain SH-B9     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 3167928..3178524
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UP12_RS16110 (UP12_16125) - 3169366..3170535 (-) 1170 WP_061409706.1 macrolide family glycosyltransferase -
  UP12_RS16115 (UP12_16130) - 3170885..3171436 (-) 552 WP_058013627.1 hypothetical protein -
  UP12_RS16130 (UP12_16145) - 3172394..3172699 (-) 306 WP_061409708.1 TM2 domain-containing protein -
  UP12_RS16135 (UP12_16150) clpP 3172928..3173524 (+) 597 WP_024719872.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  UP12_RS16140 (UP12_16155) - 3173584..3174162 (-) 579 WP_058013625.1 TIGR00730 family Rossman fold protein -
  UP12_RS16145 (UP12_16160) - 3174299..3174628 (+) 330 WP_058013624.1 MazG-like family protein -
  UP12_RS16150 (UP12_16165) - 3174657..3176279 (-) 1623 WP_061409710.1 SulP family inorganic anion transporter -
  UP12_RS16155 (UP12_16170) - 3176317..3176898 (-) 582 WP_061410273.1 carbonic anhydrase -
  UP12_RS16160 (UP12_16175) - 3177452..3178429 (+) 978 WP_058013622.1 D-glycerate dehydrogenase -

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21832.00 Da        Isoelectric Point: 4.6905

>NTDB_id=141350 UP12_RS16135 WP_024719872.1 3172928..3173524(+) (clpP) [Bacillus pumilus strain SH-B9]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLEAEDPEKDISIYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILSLRDKLNQVLAERTGQ
PIEVIERDTDRDNFKTAEEALQYGLIDKVLTRNSEEQK

Nucleotide


Download         Length: 597 bp        

>NTDB_id=141350 UP12_RS16135 WP_024719872.1 3172928..3173524(+) (clpP) [Bacillus pumilus strain SH-B9]
ATGAATTTAATACCTACAGTCATTGAGCAAACAAATCGTGGGGAAAGAGCTTACGACATTTATTCTCGTCTTTTAAAAGA
CCGTATTATCATGCTTGGTTCTGCGATCGATGACAATGTTGCCAACTCCATCGTGTCACAGCTGCTTTTCTTAGAAGCTG
AAGATCCAGAAAAAGATATTTCTATCTACATTAACAGCCCTGGCGGTTCAATTACAGCTGGTATGGCCATTTACGATACG
ATGCAATTTATTAAACCAAAGGTATCAACCATTTGTATTGGTATGGCTGCATCTATGGGTGCGTTCCTGCTTGCTGCTGG
TGAAAAAGGTAAGCGTTATGCCCTTCCAAACAGTGAAGTCATGATTCACCAACCACTAGGTGGTGCCCAAGGTCAAGCAA
CAGAAATTGAAATTGCGGCAAAACGAATCCTTTCTTTACGTGATAAACTGAACCAAGTACTTGCTGAACGTACTGGTCAG
CCAATTGAAGTCATTGAACGCGATACAGATCGTGACAACTTCAAAACAGCGGAAGAAGCACTTCAATACGGACTCATTGA
CAAAGTCTTGACCCGTAATTCAGAAGAACAAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2G8ISB7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

92.929

100

0.929
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

67.539

96.465

0.652
  clpP Streptococcus thermophilus LMG 18311

58.549

97.475

0.571
  clpP Streptococcus thermophilus LMD-9

58.549

97.475

0.571
  clpP Lactococcus lactis subsp. cremoris KW2

56.701

97.98

0.556
  clpP Streptococcus pneumoniae Rx1

56.186

97.98

0.551
  clpP Streptococcus pneumoniae D39

56.186

97.98

0.551
  clpP Streptococcus pneumoniae R6

56.186

97.98

0.551
  clpP Streptococcus pneumoniae TIGR4

56.186

97.98

0.551
  clpP Streptococcus pyogenes JRS4

55.44

97.475

0.54
  clpP Streptococcus pyogenes MGAS315

55.44

97.475

0.54
  clpP Streptococcus mutans UA159

54.639

97.98

0.535
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

54.639

97.98

0.535

Multiple sequence alignment