Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ID09_RS00300 Genome accession   NZ_CP008921
Coordinates   49805..50986 (+) Length   393 a.a.
NCBI ID   WP_024381976.1    Uniprot ID   A0A075SE29
Organism   Streptococcus suis 6407     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 44805..55986
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ID09_RS00275 (ID09_00295) mutL 45253..47190 (+) 1938 WP_024381980.1 DNA mismatch repair endonuclease MutL -
  ID09_RS00280 (ID09_00300) ruvA 47229..47819 (+) 591 WP_011921679.1 Holliday junction branch migration protein RuvA -
  ID09_RS00285 (ID09_00305) - 47978..48538 (+) 561 WP_024381979.1 DNA-3-methyladenine glycosylase I -
  ID09_RS00290 (ID09_00310) - 48612..49022 (+) 411 WP_024381978.1 helix-turn-helix transcriptional regulator -
  ID09_RS11320 (ID09_00315) - 48995..49660 (+) 666 WP_024381977.1 CPBP family intramembrane glutamic endopeptidase -
  ID09_RS00300 (ID09_00320) cinA 49805..50986 (+) 1182 WP_024381976.1 competence/damage-inducible protein A Machinery gene
  ID09_RS00305 (ID09_00325) recA 51038..52189 (+) 1152 WP_011922545.1 recombinase RecA Machinery gene
  ID09_RS00310 (ID09_00335) spx 52424..52822 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  ID09_RS00315 (ID09_00340) - 52922..53188 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  ID09_RS00320 (ID09_00345) ruvX 53188..53607 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  ID09_RS00325 (ID09_00350) - 53619..53939 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  ID09_RS00330 - 54196..54432 (+) 237 Protein_45 nucleotidyltransferase family protein -
  ID09_RS00335 (ID09_00360) rpsJ 54680..54988 (+) 309 WP_014735259.1 30S ribosomal protein S10 -
  ID09_RS00340 (ID09_00365) rplC 55201..55827 (+) 627 WP_011921686.1 50S ribosomal protein L3 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42824.66 Da        Isoelectric Point: 4.4397

>NTDB_id=125672 ID09_RS00300 WP_024381976.1 49805..50986(+) (cinA) [Streptococcus suis 6407]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNEGRLLSTLEVASKRSNMVVLCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEED
ILQHDKLADYFYAYGEDNSLAKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATTSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=125672 ID09_RS00300 WP_024381976.1 49805..50986(+) (cinA) [Streptococcus suis 6407]
ATGAAAGCAGAACTAATCGCTGTGGGTACAGAGATTTTGACAGGACAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCGGAGCTAGGGATTGATGTTTATTTTCATACGGCAGTTGGTGACAATGAAGGCCGTTTATTATCAACCCTTG
AAGTAGCCAGCAAGCGGAGTAATATGGTCGTTCTTTGCGGTGGTTTGGGACCAACTGAGGACGACCTGACCAAGCAGACC
TTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGAATTGG
CGAAAGCCAGTTGGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAAATCTACGTTTAAATCAGTTGGAAGAAGAC
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGCCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTGGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A075SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

98.473

100

0.985
  cinA Streptococcus mutans UA159

56.448

100

0.59
  cinA Streptococcus pneumoniae R6

55.769

100

0.59
  cinA Streptococcus mitis SK321

55.769

100

0.59
  cinA Streptococcus pneumoniae TIGR4

55.769

100

0.59
  cinA Streptococcus pneumoniae Rx1

55.769

100

0.59
  cinA Streptococcus mitis NCTC 12261

55.529

100

0.588
  cinA Streptococcus pneumoniae D39

55.529

100

0.588
  cinA Bacillus subtilis subsp. subtilis str. 168

40.153

99.491

0.399

Multiple sequence alignment