Detailed information NTG0124034

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: SHYC_RS06665
• Genome accession: NZ_CP008747
• Coordinates: 1396124..1396444 (+)
• Length: 106 a.a.
• NCBI ID: WP_039645583.1
• Uniprot ID: A0A0A8HQY4
• Organism: Staphylococcus hyicus strain ATCC 11249
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1391124..1401444

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SHYC_RS06635 (SHYC_06840)	-	1391909..1392112 (+)	204	WP_039645571.1	YqgQ family protein	-
SHYC_RS06640 (SHYC_06845)	-	1392109..1393095 (+)	987	WP_039645573.1	ROK family glucokinase	-
SHYC_RS06645 (SHYC_06850)	-	1393097..1393408 (+)	312	WP_039645576.1	MTH1187 family thiamine-binding protein	-
SHYC_RS06650 (SHYC_06855)	-	1393423..1394046 (+)	624	WP_039645578.1	MBL fold metallo-hydrolase	-
SHYC_RS06655 (SHYC_06860)	comGA	1394102..1395076 (+)	975	WP_039645580.1	competence type IV pilus ATPase ComGA	Machinery gene
SHYC_RS06660 (SHYC_06865)	comGB	1395045..1396112 (+)	1068	WP_039645581.1	competence type IV pilus assembly protein ComGB	-
SHYC_RS06665 (SHYC_06870)	comGC	1396124..1396444 (+)	321	WP_039645583.1	competence type IV pilus major pilin ComGC	Machinery gene
SHYC_RS06670 (SHYC_06875)	comGD	1396434..1396865 (+)	432	WP_231912771.1	competence type IV pilus minor pilin ComGD	-
SHYC_RS06675 (SHYC_06880)	-	1397058..1397540 (+)	483	WP_039645587.1	competence type IV pilus minor pilin ComGF	-
SHYC_RS06680 (SHYC_06888)	-	1397524..1397721 (+)	198	WP_039645590.1	hypothetical protein	-
SHYC_RS06685 (SHYC_06890)	-	1397699..1398229 (+)	531	WP_039645592.1	shikimate kinase	-
SHYC_RS06690 (SHYC_06895)	gcvT	1398384..1399475 (+)	1092	WP_039645594.1	glycine cleavage system aminomethyltransferase GcvT	-
SHYC_RS06695 (SHYC_06900)	gcvPA	1399487..1400836 (+)	1350	WP_039645597.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-

Sequence

Protein

• Length: 106 a.a.
• Molecular weight: 11838.11 Da
• Isoelectric Point: 9.5056

>NTDB_id=124034 SHYC_RS06665 WP_039645583.1 1396124..1396444(+) (comGC) [Staphylococcus hyicus strain ATCC 11249]
MLKIINILKNKKGFTLIEMLLVLLIISVLLILIIPNIAKQSEHIQKTGCAAQLKLVDSQIEAYTLKYNRKPTSIDELIQE
GYIKDNQKNCKSGETITIRGGEAVVS

Nucleotide

• Length: 321 bp

>NTDB_id=124034 SHYC_RS06665 WP_039645583.1 1396124..1396444(+) (comGC) [Staphylococcus hyicus strain ATCC 11249]
ATGCTTAAGATCATTAATATATTAAAAAACAAAAAAGGGTTTACTTTAATCGAAATGTTATTGGTTTTACTCATCATTAG
TGTTTTATTAATATTAATAATTCCTAATATAGCCAAACAATCTGAGCACATTCAAAAGACTGGATGCGCGGCACAACTTA
AACTCGTAGACAGTCAAATTGAAGCTTACACTTTAAAATACAACCGTAAGCCAACATCAATTGATGAGCTAATTCAAGAA
GGATATATTAAAGATAATCAAAAAAACTGTAAAAGTGGGGAAACTATCACAATTCGTGGTGGCGAAGCTGTTGTCTCATA
A

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (9-33)

3D structure

• AlphaFold DB: A0A0A8HQY4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Staphylococcus aureus N315	68.932	97.17	0.67
comGC	Staphylococcus aureus MW2	68.932	97.17	0.67
comGC	Bacillus subtilis subsp. subtilis str. 168	44.792	90.566	0.406
comGC/cglC	Streptococcus mitis SK321	47.191	83.962	0.396
comGC/cglC	Streptococcus mitis NCTC 12261	47.191	83.962	0.396
comGC/cglC	Streptococcus pneumoniae R6	46.067	83.962	0.387
comGC/cglC	Streptococcus pneumoniae Rx1	46.067	83.962	0.387
comGC/cglC	Streptococcus pneumoniae TIGR4	46.067	83.962	0.387
comGC/cglC	Streptococcus pneumoniae D39	46.067	83.962	0.387
comYC	Streptococcus suis isolate S10	51.316	71.698	0.368