Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   FE90_RS00580 Genome accession   NZ_CP008695
Coordinates   96837..97775 (+) Length   312 a.a.
NCBI ID   WP_032460336.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M23ND     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 91837..102775
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FE90_RS00570 (FE90_0080) rpoC 92586..96227 (+) 3642 WP_032460334.1 DNA-directed RNA polymerase subunit beta' -
  FE90_RS00575 (FE90_0081) - 96379..96744 (+) 366 WP_002986560.1 DUF1033 family protein -
  FE90_RS00580 (FE90_0082) comYA 96837..97775 (+) 939 WP_032460336.1 competence type IV pilus ATPase ComGA Machinery gene
  FE90_RS00585 (FE90_0083) comYB 97711..98745 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  FE90_RS00590 (FE90_0084) comYC 98747..99073 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  FE90_RS00595 (FE90_0085) comGD 99048..99476 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  FE90_RS00600 (FE90_0086) comGE 99433..99717 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  FE90_RS00605 (FE90_0087) comYF 99710..100144 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  FE90_RS00610 (FE90_0088) comGG 100128..100454 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  FE90_RS00615 (FE90_0089) comYH 100552..101505 (+) 954 WP_038433084.1 class I SAM-dependent methyltransferase Machinery gene
  FE90_RS00620 (FE90_0090) - 101564..102760 (+) 1197 WP_038433085.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35044.33 Da        Isoelectric Point: 9.1037

>NTDB_id=123564 FE90_RS00580 WP_032460336.1 96837..97775(+) (comYA) [Streptococcus pyogenes strain M23ND]
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLVSHFKFVAGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISNYHQKA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=123564 FE90_RS00580 WP_032460336.1 96837..97775(+) (comYA) [Streptococcus pyogenes strain M23ND]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTGTTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTCAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAGGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAATTATCATCAAAAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGCAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

61.415

99.679

0.612
  comYA Streptococcus mutans UA140

61.415

99.679

0.612
  comYA Streptococcus gordonii str. Challis substr. CH1

60.45

99.679

0.603
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.323

99.359

0.599
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

58.521

99.679

0.583
  comGA/cglA/cilD Streptococcus pneumoniae D39

58.521

99.679

0.583
  comGA/cglA/cilD Streptococcus pneumoniae R6

58.521

99.679

0.583
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

58.521

99.679

0.583
  comGA Lactococcus lactis subsp. cremoris KW2

50.482

99.679

0.503
  comGA Latilactobacillus sakei subsp. sakei 23K

39.655

92.949

0.369

Multiple sequence alignment