Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EN73_RS09875 Genome accession   NZ_CP007632
Coordinates   1966971..1968230 (-) Length   419 a.a.
NCBI ID   WP_001200978.1    Uniprot ID   A0AAW6XW56
Organism   Streptococcus agalactiae strain NGBS572     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1961971..1973230
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EN73_RS09840 (EN73_09985) - 1962123..1963664 (-) 1542 WP_000230040.1 membrane protein -
  EN73_RS11155 - 1963710..1963832 (-) 123 WP_001285711.1 hypothetical protein -
  EN73_RS09850 (EN73_09995) - 1963914..1964231 (-) 318 WP_000940932.1 DUF1292 domain-containing protein -
  EN73_RS09855 (EN73_10000) ruvX 1964257..1964676 (-) 420 WP_001222109.1 Holliday junction resolvase RuvX -
  EN73_RS09860 (EN73_10005) - 1964676..1964942 (-) 267 WP_000507056.1 IreB family regulatory phosphoprotein -
  EN73_RS09865 (EN73_10010) spx 1965144..1965542 (-) 399 WP_000591161.1 transcriptional regulator Spx -
  EN73_RS09870 (EN73_10015) recA 1965758..1966897 (-) 1140 WP_001085741.1 recombinase RecA Machinery gene
  EN73_RS09875 (EN73_10020) cinA 1966971..1968230 (-) 1260 WP_001200978.1 competence/damage-inducible protein A Machinery gene
  EN73_RS09880 (EN73_10025) - 1968319..1968870 (-) 552 WP_000817341.1 DNA-3-methyladenine glycosylase I -
  EN73_RS09885 (EN73_10030) ruvA 1968893..1969483 (-) 591 WP_000272487.1 Holliday junction branch migration protein RuvA -
  EN73_RS09890 (EN73_10035) - 1969485..1970717 (-) 1233 WP_000657476.1 MDR family MFS transporter -
  EN73_RS09895 (EN73_10040) mutL 1970749..1972722 (-) 1974 WP_000034617.1 DNA mismatch repair endonuclease MutL -
  EN73_RS09900 (EN73_10045) - 1972948..1973151 (+) 204 WP_000191849.1 cold-shock protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45498.34 Da        Isoelectric Point: 6.3076

>NTDB_id=121912 EN73_RS09875 WP_001200978.1 1966971..1968230(-) (cinA) [Streptococcus agalactiae strain NGBS572]
MRAEIIAVGTEILTGQIVNTNAQFLSEKMAELGIDIYFQTAVGDNEERLLSLLDIASQRSQLVILCGGLGPTEDDLTKQT
LAKFLGKSLTVDLLASRKLDRFFSSRPQFARTPNNERQAQLVEGSIPLQNLTGLAVGGIVTSKGVQYMVLPGPPSELKPM
VMEQVVPILSNNGTKLYSRVLRFFGIGESQLVTILEDIIKNQTDPTIAPYAKVGEVTLRLSTKAENQDEADFKLDSLEKE
ILALKTLDNRKLKDLLYGYGDNNSMARTVLELLKVQNKTITAAESLTAGLFQSQLAEFSGASQVFNGGFTTYSMEAKSQL
LGIPKKKLQEYGVVSHFTAEAMAQQARQLLKADFGIGLTGVAGPDELEGYPAGTVFIGIATPEGVSSIKVSIGGKSRSDV
RHISTLHAFDLVRRALLKI

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=121912 EN73_RS09875 WP_001200978.1 1966971..1968230(-) (cinA) [Streptococcus agalactiae strain NGBS572]
GTGAGGGCTGAAATTATCGCTGTAGGAACAGAAATTTTAACAGGACAGATCGTTAATACAAACGCACAATTTTTGTCGGA
GAAAATGGCAGAATTGGGAATTGATATTTATTTCCAGACAGCTGTAGGAGACAATGAGGAACGTTTATTATCGCTTTTAG
ATATAGCTAGTCAGCGCAGTCAATTGGTTATCCTATGTGGTGGACTTGGCCCTACAGAGGATGACTTAACGAAGCAAACT
TTGGCTAAATTTTTAGGTAAATCATTAACAGTAGATTTATTAGCTAGTCGAAAATTGGATCGTTTTTTTTCAAGTCGTCC
TCAGTTTGCTAGAACGCCAAATAATGAACGACAAGCTCAATTGGTTGAAGGCTCAATACCTCTACAAAACCTTACTGGTC
TAGCTGTTGGTGGTATCGTTACATCTAAGGGAGTCCAATATATGGTTTTACCAGGTCCGCCTAGTGAATTAAAGCCAATG
GTTATGGAGCAGGTAGTACCTATTTTGTCAAATAATGGCACAAAATTATATTCACGTGTATTGAGATTCTTTGGTATCGG
TGAGAGTCAGTTAGTCACAATCTTAGAAGACATAATTAAGAATCAGACAGACCCAACTATAGCACCATATGCAAAGGTTG
GTGAGGTAACTTTAAGGTTATCAACGAAAGCTGAAAATCAGGATGAGGCCGACTTTAAATTAGATAGCTTAGAAAAAGAA
ATACTTGCTCTTAAGACATTAGATAACCGTAAATTAAAAGATTTATTATATGGTTATGGTGATAATAATAGTATGGCACG
TACTGTTTTAGAATTATTGAAAGTACAAAATAAAACGATTACTGCCGCAGAGAGCTTAACAGCAGGGTTATTTCAATCTC
AGTTAGCAGAATTTTCTGGTGCTTCGCAAGTTTTTAATGGTGGTTTTACGACCTATAGTATGGAAGCAAAATCACAACTT
CTCGGCATCCCTAAGAAAAAATTGCAAGAATATGGAGTTGTCAGTCATTTTACAGCTGAGGCAATGGCTCAGCAAGCTCG
CCAACTTTTAAAAGCAGATTTTGGTATCGGTTTAACGGGAGTTGCTGGTCCTGATGAGTTGGAAGGATACCCTGCAGGTA
CAGTTTTTATTGGGATTGCAACCCCTGAAGGCGTTTCTTCTATTAAAGTATCGATTGGAGGGAAGAGTCGCTCAGATGTC
CGTCATATCAGTACTTTACATGCTTTTGACTTGGTGCGTAGGGCTTTATTAAAGATATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(263-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

71.463

99.523

0.711
  cinA Streptococcus mitis NCTC 12261

71.223

99.523

0.709
  cinA Streptococcus pneumoniae TIGR4

70.264

99.523

0.699
  cinA Streptococcus pneumoniae Rx1

70.024

99.523

0.697
  cinA Streptococcus pneumoniae R6

70.024

99.523

0.697
  cinA Streptococcus pneumoniae D39

69.784

99.523

0.695
  cinA Streptococcus mutans UA159

68.106

99.523

0.678
  cinA Streptococcus suis isolate S10

54.567

99.284

0.542
  cinA Bacillus subtilis subsp. subtilis str. 168

43.541

99.761

0.434

Multiple sequence alignment