Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   DK43_RS06550 Genome accession   NZ_CP007573
Coordinates   1353712..1354413 (-) Length   233 a.a.
NCBI ID   WP_003027677.1    Uniprot ID   A0AAI9NI07
Organism   Streptococcus anginosus strain SA1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1348712..1359413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK43_RS06530 (DK43_06710) rnc 1350121..1350819 (-) 699 WP_003027666.1 ribonuclease III -
  DK43_RS06535 (DK43_06715) - 1351192..1351552 (-) 361 Protein_1302 DUF454 family protein -
  DK43_RS06540 (DK43_06720) vicX 1351561..1352364 (-) 804 WP_021001533.1 MBL fold metallo-hydrolase Regulator
  DK43_RS06545 (DK43_06725) micB 1352367..1353719 (-) 1353 WP_021001532.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DK43_RS06550 (DK43_06730) micA 1353712..1354413 (-) 702 WP_003027677.1 response regulator YycF Regulator
  DK43_RS06555 (DK43_06735) - 1354698..1355039 (-) 342 WP_003027678.1 hypothetical protein -
  DK43_RS06560 (DK43_06740) - 1355066..1356379 (-) 1314 WP_022525097.1 glycosyltransferase family 4 protein -
  DK43_RS06565 (DK43_06745) - 1356381..1357379 (-) 999 WP_022525098.1 glycosyltransferase -
  DK43_RS06570 (DK43_06750) ccpA 1357559..1358563 (-) 1005 WP_003027685.1 catabolite control protein A Regulator

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26972.97 Da        Isoelectric Point: 4.6957

>NTDB_id=121213 DK43_RS06550 WP_003027677.1 1353712..1354413(-) (micA) [Streptococcus anginosus strain SA1]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAERPDILILDLMLPEMDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAEPKEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=121213 DK43_RS06550 WP_003027677.1 1353712..1354413(-) (micA) [Streptococcus anginosus strain SA1]
ATGAAAAAAATATTAGTTGTAGATGATGAAAAACCAATCTCAGATATCATAAAATTTAACATGGTAAAAGAAGGTTATGA
GGTAGTGACAGCCTTCGACGGTCGCGAAGCGTTAGAGATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTGA
TGTTGCCCGAAATGGACGGCTTAGAGGTGGCGCGAACGATTCGGAAAACGAGTAATGTGCCAATCATCGTTCTTTCTGCC
AAAGACAGTGAATTTGACAAAGTTATTGGTCTTGAGATTGGTGCAGATGACTATATGACAAAGCCTTTCTCTAATCGTGA
ATTGCAGGCGCGTGTCAAAGCCATTTTGCGGCGGACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGAACCAAAAG
AAATTGTGATTGGAGATCTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGGCGAAGAATTAGATTTAACACAC
CGTGAGTTTGAATTGCTACACCATTTGGCCACGCATATCGGGCAAGTGATGACGCGTGAACATCTGCTAGAAACGGTGTG
GGGTTATGATTATTTTGGAGATGTGCGGACTGTTGATGTGACAATTCGTCGTTTGAGAGAAAAGATAGAGGATATTCCTA
GCCGACCAGAGTACATTTTAACGCGGCGCGGCGTTGGATATTACATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.833

100

0.828
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Streptococcus salivarius strain HSISS4

44.978

98.283

0.442
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  scnR Streptococcus mutans UA159

36.052

100

0.361

Multiple sequence alignment