Detailed information NTG0121212

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: DK43_RS06545
• Genome accession: NZ_CP007573
• Coordinates: 1352367..1353719 (-)
• Length: 450 a.a.
• NCBI ID: WP_021001532.1
• Uniprot ID: A0AAP6BQL7
• Organism: Streptococcus anginosus strain SA1
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1347367..1358719

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK43_RS06530 (DK43_06710)	rnc	1350121..1350819 (-)	699	WP_003027666.1	ribonuclease III	-
DK43_RS06535 (DK43_06715)	-	1351192..1351552 (-)	361	Protein_1302	DUF454 family protein	-
DK43_RS06540 (DK43_06720)	vicX	1351561..1352364 (-)	804	WP_021001533.1	MBL fold metallo-hydrolase	Regulator
DK43_RS06545 (DK43_06725)	micB	1352367..1353719 (-)	1353	WP_021001532.1	cell wall metabolism sensor histidine kinase VicK	Regulator
DK43_RS06550 (DK43_06730)	micA	1353712..1354413 (-)	702	WP_003027677.1	response regulator YycF	Regulator
DK43_RS06555 (DK43_06735)	-	1354698..1355039 (-)	342	WP_003027678.1	hypothetical protein	-
DK43_RS06560 (DK43_06740)	-	1355066..1356379 (-)	1314	WP_022525097.1	glycosyltransferase family 4 protein	-
DK43_RS06565 (DK43_06745)	-	1356381..1357379 (-)	999	WP_022525098.1	glycosyltransferase	-
DK43_RS06570 (DK43_06750)	ccpA	1357559..1358563 (-)	1005	WP_003027685.1	catabolite control protein A	Regulator

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51362.59 Da
• Isoelectric Point: 4.6876

>NTDB_id=121212 DK43_RS06545 WP_021001532.1 1352367..1353719(-) (micB) [Streptococcus anginosus strain SA1]
MIDNIRQFIVSKDFVFVLLILGFILVITLLSLENRRDNVRIRQLNQKVKDLIAGNYSEILDVQGGPEITDITNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIIMINDMATKQLGVKESEARKMNILKLLDIEDEYDLRDLITKVPE
LTIDSQDENGEFLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVSDLLSLSRIDNATSHLDIELTNFTAFITFILNRFDKIRSQNDDKKYEIIRDYPINSIW
VEIDTDKMTQVIDNIINNAIKYSPDGGKITVSMKTTDTQMILSISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKEAVKDDDWEEDELEG

Nucleotide

• Length: 1353 bp

>NTDB_id=121212 DK43_RS06545 WP_021001532.1 1352367..1353719(-) (micB) [Streptococcus anginosus strain SA1]
ATGATTGATAATATTAGACAATTTATTGTATCAAAAGACTTTGTATTTGTTTTACTTATTTTAGGGTTCATCTTGGTGAT
TACCTTGCTTTCCTTGGAAAACAGGCGTGACAACGTTCGTATTCGCCAATTGAATCAAAAAGTAAAAGATTTAATTGCAG
GCAATTACTCAGAAATTTTAGATGTACAAGGTGGTCCAGAAATTACGGATATTACCAACAGTATCAATGATTTATCTGAG
GTAATCCGTCTAACGCATGAAAATTTAGAGCAAGAAACTAAGCGCCTGTCGAGTATTTTATCCTATATGACGGACGGCGT
TCTTGCGACCAATCGTCGTGGGCAGATTATCATGATTAATGATATGGCGACCAAGCAGTTGGGGGTCAAAGAATCCGAAG
CACGAAAGATGAATATCTTAAAACTGTTGGATATCGAAGACGAATATGACTTACGAGACTTGATTACGAAAGTTCCAGAA
TTGACCATTGATTCGCAGGATGAAAATGGAGAGTTTTTAAGTTTACGTGTTCGATTTGCCTTGATTCGGCGAGAATCAGG
CTTTATTTCAGGGCTGGTTGCAGTGTTACACGATACAACGGAGCAGGAAAAAGAAGAGCGTGAGCGGAGACTGTTTGTTT
CGAATGTCAGTCACGAATTACGTACTCCCTTGACCAGTGTCAAGTCTTATCTGGAAGCACTAGATGAAGGTGCCTTATCA
GAACCAGTCGCACCGGATTTCATCAAGGTTTCATTAGACGAGACAAATCGGATGATGCGCATGGTTTCGGACTTGCTGAG
TTTGTCACGTATTGACAATGCAACCAGTCATTTGGATATTGAATTGACGAATTTTACAGCTTTTATCACCTTTATTTTGA
ACCGTTTTGATAAAATCAGAAGCCAGAATGATGATAAAAAGTATGAAATTATACGAGATTATCCGATTAACTCTATTTGG
GTCGAAATTGATACAGATAAGATGACACAGGTGATTGATAATATTATCAACAATGCCATTAAATATTCTCCTGACGGTGG
TAAAATTACGGTCAGTATGAAAACGACGGATACCCAAATGATTTTGTCGATTTCAGATGAAGGCTTAGGAATTCCTAAAA
AAGATTTGCCGAAAATTTTTGATAGATTTTATCGTGTAGACAAAGCAAGAAGTCGCGCCCAAGGTGGATCCGGACTGGGC
TTAGCCATTGCCAAAGAGATTATCAAGCAACATAACGGCTTTATCTGGGCAAAGAGCGAGTACGGCAAAGGCTCGACGTT
TACAATCGTTCTGCCATATGACAAAGAAGCTGTCAAAGATGATGATTGGGAAGAAGATGAATTAGAAGGATAG

Domains

Predicted by InterproScan.

• PAS fold (PAS) (95-198)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	80.866	97.556	0.789
vicK	Streptococcus mutans UA159	71.883	90.889	0.653