Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   DK43_RS05745 Genome accession   NZ_CP007573
Coordinates   1188433..1189137 (-) Length   234 a.a.
NCBI ID   WP_003029859.1    Uniprot ID   A0AAI9NIK1
Organism   Streptococcus anginosus strain SA1     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1183433..1194137
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK43_RS05730 (DK43_05900) - 1183912..1184898 (-) 987 WP_022525428.1 Gfo/Idh/MocA family oxidoreductase -
  DK43_RS05735 (DK43_05910) - 1185442..1186140 (-) 699 WP_003029857.1 DUF805 domain-containing protein -
  DK43_RS05740 (DK43_05915) comEC/celB 1186221..1188449 (-) 2229 WP_003029858.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DK43_RS05745 (DK43_05920) comEA/celA/cilE 1188433..1189137 (-) 705 WP_003029859.1 helix-hairpin-helix domain-containing protein Machinery gene
  DK43_RS05750 (DK43_05925) smpB 1189319..1189786 (-) 468 WP_003029860.1 SsrA-binding protein SmpB -
  DK43_RS05755 (DK43_05930) rnr 1189749..1192082 (-) 2334 WP_003029862.1 ribonuclease R -
  DK43_RS05760 (DK43_05935) secG 1192174..1192407 (-) 234 WP_003024744.1 preprotein translocase subunit SecG -
  DK43_RS10130 rpmG 1192447..1192596 (-) 150 WP_003024746.1 50S ribosomal protein L33 -
  DK43_RS05765 (DK43_05940) - 1192580..1193785 (-) 1206 WP_003029864.1 multidrug efflux MFS transporter -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 24996.03 Da        Isoelectric Point: 5.4996

>NTDB_id=121209 DK43_RS05745 WP_003029859.1 1188433..1189137(-) (comEA/celA/cilE) [Streptococcus anginosus strain SA1]
MLETIIEKMKEYKILIGLSLIGLIIAGFFMINGQSSRQSNVAELAQETVTSSEAESKEISTRTKKNSQKEKAETQTSSSE
ESEFLTVDVKGAVKNPGIYQLKKTSRINDAIQKAGGLTTDADSKSINLAQKLTDEAVVYVATVGENATSVASGTGQSSTS
GTSKVASQKGNKVNLNTADLSELQTISGIGQKRAQDILDYREANGKFSSVDDLKNVSGVGAKTLEKLKEYVTVD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=121209 DK43_RS05745 WP_003029859.1 1188433..1189137(-) (comEA/celA/cilE) [Streptococcus anginosus strain SA1]
ATGTTAGAGACAATCATTGAGAAGATGAAAGAGTATAAAATTTTGATTGGTTTAAGTTTGATTGGTTTGATAATAGCAGG
ATTTTTTATGATAAATGGTCAATCTAGTAGACAATCAAATGTAGCAGAGCTCGCACAGGAAACAGTTACGAGTTCGGAGG
CAGAATCAAAAGAAATTTCAACTAGAACGAAGAAAAACTCACAGAAAGAAAAAGCAGAGACTCAAACGAGTTCAAGTGAA
GAATCAGAATTTTTAACCGTAGATGTCAAGGGTGCAGTCAAAAATCCAGGTATTTATCAACTGAAAAAGACTAGCCGTAT
CAATGATGCAATTCAAAAAGCGGGTGGTTTAACGACAGACGCTGACAGCAAGTCTATCAATTTGGCGCAAAAACTAACAG
ATGAAGCTGTTGTTTATGTGGCAACTGTTGGCGAGAATGCGACAAGTGTTGCAAGCGGAACAGGACAATCTTCAACGTCA
GGAACTAGTAAAGTCGCATCGCAAAAAGGGAATAAGGTCAATCTAAATACAGCTGATTTATCTGAGTTGCAGACCATTTC
TGGCATCGGTCAAAAACGTGCGCAAGATATTTTAGATTATCGTGAGGCAAACGGGAAATTCAGTTCAGTTGATGACCTGA
AAAATGTATCAGGAGTTGGTGCCAAAACACTAGAAAAATTGAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(87-140)

Helix-hairpin-helix motif (HHH_3)

(169-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae R6

52.361

99.573

0.521
  comEA/celA/cilE Streptococcus mitis NCTC 12261

52.361

99.573

0.521
  comEA/celA/cilE Streptococcus pneumoniae Rx1

52.361

99.573

0.521
  comEA/celA/cilE Streptococcus pneumoniae D39

52.361

99.573

0.521
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

51.931

99.573

0.517
  comEA/celA/cilE Streptococcus mitis SK321

51.073

99.573

0.509
  comEA Streptococcus thermophilus LMD-9

44.681

100

0.449
  comEA Lactococcus lactis subsp. cremoris KW2

42.06

99.573

0.419

Multiple sequence alignment