Detailed information NTG0121208

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: DK43_RS05740
• Genome accession: NZ_CP007573
• Coordinates: 1186221..1188449 (-)
• Length: 742 a.a.
• NCBI ID: WP_003029858.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain SA1
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1181221..1193449

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK43_RS05715 (DK43_05885)	-	1181440..1182717 (-)	1278	WP_003029848.1	dihydroorotase	-
DK43_RS05720 (DK43_05890)	-	1182730..1183200 (-)	471	WP_003029850.1	8-oxo-dGTP diphosphatase	-
DK43_RS05725 (DK43_05895)	-	1183237..1183890 (-)	654	WP_003029851.1	uracil-DNA glycosylase	-
DK43_RS05730 (DK43_05900)	-	1183912..1184898 (-)	987	WP_022525428.1	Gfo/Idh/MocA family oxidoreductase	-
DK43_RS05735 (DK43_05910)	-	1185442..1186140 (-)	699	WP_003029857.1	DUF805 domain-containing protein	-
DK43_RS05740 (DK43_05915)	comEC/celB	1186221..1188449 (-)	2229	WP_003029858.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DK43_RS05745 (DK43_05920)	comEA/celA/cilE	1188433..1189137 (-)	705	WP_003029859.1	helix-hairpin-helix domain-containing protein	Machinery gene
DK43_RS05750 (DK43_05925)	smpB	1189319..1189786 (-)	468	WP_003029860.1	SsrA-binding protein SmpB	-
DK43_RS05755 (DK43_05930)	rnr	1189749..1192082 (-)	2334	WP_003029862.1	ribonuclease R	-
DK43_RS05760 (DK43_05935)	secG	1192174..1192407 (-)	234	WP_003024744.1	preprotein translocase subunit SecG	-
DK43_RS10130	rpmG	1192447..1192596 (-)	150	WP_003024746.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 85067.86 Da
• Isoelectric Point: 10.0445

>NTDB_id=121208 DK43_RS05740 WP_003029858.1 1186221..1188449(-) (comEC/celB) [Streptococcus anginosus strain SA1]
MSQWIKRFPIKPIYIAFLLVWLYFAIYQSSWLACLGFIFLVIRLFRFYSPKEYFMTFMILSCFAGFFFVRREMVEQKTKV
APSPVRQVAVLPDTIKVNGDSLSFRGKTNGQTYQVYYKLKSKEEQLAFQNLSSLAILTVEGEFEIPEKKRNFAGFDYQSY
LKTQGIYRILKVDTILSSQDRISLHTFEWLSSWRRRALVFIKKHFPNPMSNYMTGLLFGALDTDFDEMNNLYSSLGIIHL
FALSGMQVGFFMEGFRKLLLRLGLTQEMVHKCQYPFSFFYAGMTGFSVSVVRSLVQKLLSQHGITKLDNFALTMMILSLI
MPSFLLTAGGVLSCAYAFVISVIDFESLTSWRKIVVESSVISLGVLPILIFYFGEFQPWSILLTFVFSLIFDTMMLPGLT
LIFLSSPLIKLTQVNFLFEGLENSIRWIASVFGRPIVFGQPSPLLLIVMLLVLAILYDIRKNKKWVIFLSLLLSLLFFIN
KFPLQNEITMVDVGQGDSIFLRDWKGRNVLIDVGGREEIRTKEAWQKRATSSNAEKTLIPYLKSRGIDTIDALVLTNPNP
DYAGDVLEVAKKFAIKKIYISRSSLSNADFLEKLRKINTFIHVVKQGDKLPIFDHHLQVLSGASKNDHSIVLYGQFFRTR
FLFASDLKEEGEAKLMQHYPKLKTDVLKVGQHGAKDSSSSKFLQQIEPTVALISVGKNNQSKQPSQDTIERFAQLPAKVY
RTDEQGAVKFSGWTNWRLEMVK

Nucleotide

• Length: 2229 bp

>NTDB_id=121208 DK43_RS05740 WP_003029858.1 1186221..1188449(-) (comEC/celB) [Streptococcus anginosus strain SA1]
ATGTCACAGTGGATTAAAAGATTTCCGATTAAGCCAATTTACATAGCTTTTTTGCTTGTCTGGTTATATTTTGCAATCTA
CCAAAGTAGTTGGTTAGCTTGTCTTGGTTTTATCTTTCTAGTGATTCGTCTTTTTCGCTTTTATTCACCGAAAGAATATT
TCATGACCTTCATGATCCTCTCTTGTTTTGCTGGTTTTTTCTTTGTTCGTAGGGAAATGGTAGAGCAGAAGACGAAAGTA
GCACCCTCTCCCGTAAGACAAGTAGCAGTTCTACCTGACACGATTAAGGTAAATGGAGATTCACTTTCTTTCCGTGGTAA
AACAAATGGGCAGACTTATCAAGTTTACTACAAATTGAAATCAAAGGAAGAACAGTTGGCTTTTCAAAATCTCTCTAGTC
TGGCTATATTGACCGTTGAAGGGGAATTTGAAATCCCTGAGAAGAAGCGTAATTTTGCTGGTTTTGATTACCAATCCTAT
TTAAAAACGCAAGGGATTTATCGAATTTTAAAAGTGGATACCATTTTATCGAGCCAAGATAGAATCAGCTTGCACACTTT
TGAGTGGCTTTCTAGCTGGCGAAGAAGAGCACTGGTATTTATCAAGAAGCATTTTCCAAATCCGATGAGTAATTACATGA
CAGGACTCTTATTTGGTGCCTTGGATACAGACTTCGATGAAATGAACAATCTTTACTCTAGCTTGGGGATTATTCATTTA
TTTGCGCTGTCTGGCATGCAAGTTGGTTTTTTTATGGAGGGTTTTCGTAAGTTGCTGTTAAGGCTGGGTCTTACACAGGA
AATGGTCCATAAATGTCAATATCCATTTTCTTTCTTCTATGCGGGAATGACTGGATTTTCAGTATCCGTTGTACGGAGCT
TAGTTCAGAAATTACTGTCGCAACATGGTATCACTAAGTTAGATAATTTTGCTTTAACGATGATGATATTGTCCTTGATT
ATGCCTTCCTTTCTTTTAACGGCAGGAGGAGTTCTCTCTTGCGCCTATGCTTTTGTTATTAGTGTGATAGATTTTGAAAG
TCTGACTTCTTGGCGAAAGATTGTTGTAGAGAGCAGTGTCATTTCGCTTGGTGTTTTACCGATTCTAATCTTTTATTTTG
GTGAATTTCAACCTTGGTCTATTTTGTTGACATTTGTTTTTTCACTGATTTTCGATACAATGATGCTGCCAGGCTTGACG
TTGATTTTTCTTTCTTCGCCTTTGATAAAGCTAACTCAGGTCAATTTTCTATTTGAAGGGTTAGAAAATAGCATTCGTTG
GATAGCAAGTGTCTTTGGCAGACCAATCGTTTTTGGGCAACCCAGTCCGCTTTTGCTGATTGTTATGCTACTTGTACTGG
CTATTTTGTATGATATTAGAAAAAATAAAAAATGGGTAATATTTCTTAGTCTGCTTCTTTCATTACTCTTTTTCATAAAT
AAATTTCCTTTGCAAAATGAGATCACAATGGTTGATGTTGGGCAGGGAGATAGTATTTTTCTGAGAGACTGGAAAGGACG
AAATGTATTGATTGATGTTGGTGGACGTGAGGAAATTAGAACAAAAGAAGCTTGGCAAAAACGAGCGACTAGCTCAAATG
CAGAGAAAACTTTGATTCCTTACTTAAAAAGTCGTGGCATAGATACGATTGATGCTTTAGTCTTAACAAATCCTAATCCA
GATTATGCAGGAGATGTATTAGAAGTTGCTAAAAAATTTGCAATAAAGAAAATTTATATTTCTAGAAGTAGTCTAAGCAA
TGCAGATTTTCTAGAGAAATTAAGGAAAATAAACACATTCATTCATGTTGTAAAACAAGGCGACAAACTTCCTATTTTTG
ATCATCATTTGCAAGTTCTTTCGGGTGCTAGCAAGAACGACCATTCGATCGTTTTATATGGTCAGTTTTTCCGTACAAGA
TTTTTATTTGCGAGCGACTTGAAAGAAGAGGGCGAAGCAAAGTTAATGCAGCATTATCCAAAGTTGAAAACAGATGTTTT
GAAAGTCGGACAGCATGGAGCCAAGGACTCATCAAGTTCAAAATTTTTGCAACAAATAGAACCAACGGTTGCGCTCATTT
CTGTCGGGAAAAATAATCAATCTAAGCAACCAAGCCAAGATACAATAGAGCGATTTGCACAATTGCCTGCTAAAGTCTAT
CGGACAGATGAACAAGGGGCAGTTAAATTTTCAGGGTGGACAAACTGGCGATTAGAGATGGTCAAGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-460)

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-695)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	55.556	100	0.559
comEC/celB	Streptococcus mitis NCTC 12261	54.96	100	0.553
comEC/celB	Streptococcus pneumoniae TIGR4	54.618	100	0.55
comEC/celB	Streptococcus pneumoniae Rx1	53.681	100	0.54
comEC/celB	Streptococcus pneumoniae D39	53.681	100	0.54
comEC/celB	Streptococcus pneumoniae R6	53.681	100	0.54
comEC	Lactococcus lactis subsp. cremoris KW2	47.39	100	0.477