Detailed information NTG0121207

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: DK43_RS05325
• Genome accession: NZ_CP007573
• Coordinates: 1098686..1099528 (+)
• Length: 280 a.a.
• NCBI ID: WP_003042009.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain SA1
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1093686..1104528

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK43_RS05300 (DK43_05460)	-	1094677..1095594 (+)	918	WP_003029674.1	MBL fold metallo-hydrolase	-
DK43_RS05305 (DK43_05465)	ylqF	1095714..1096565 (+)	852	WP_003029675.1	ribosome biogenesis GTPase YlqF	-
DK43_RS05310 (DK43_05470)	-	1096552..1097334 (+)	783	WP_003029676.1	ribonuclease HII	-
DK43_RS05315 (DK43_05475)	-	1097331..1098158 (+)	828	WP_003029677.1	PRD domain-containing protein	-
DK43_RS05320 (DK43_05480)	-	1098148..1098603 (+)	456	WP_003029678.1	sugar O-acetyltransferase	-
DK43_RS05325 (DK43_05485)	dprA/cilB/dalA	1098686..1099528 (+)	843	WP_003042009.1	DNA-processing protein DprA	Machinery gene
DK43_RS05330 (DK43_05490)	topA	1099614..1101707 (+)	2094	WP_003029680.1	type I DNA topoisomerase	-
DK43_RS05335 (DK43_05495)	-	1101771..1102268 (+)	498	WP_003029682.1	hypothetical protein	-
DK43_RS05340 (DK43_05500)	trmFO	1102443..1103777 (+)	1335	WP_003042069.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31085.63 Da
• Isoelectric Point: 5.4086

>NTDB_id=121207 DK43_RS05325 WP_003042009.1 1098686..1099528(+) (dprA/cilB/dalA) [Streptococcus anginosus strain SA1]
MDNFDIYKLKKAGLTNQQVINVLSYAEIQDKELSVKDMAVVSECRNPALFIEKYLQLDDDLLCQEFEKFPSFSILDDVYP
WDLSEIYNPPVLLFYKGNLDLLKLPKVAVVGSRNSSRTGSQSVQKIVKELNNELVIVSGLARGIDTSAHMAALQNGGRTI
AVIGTGLDVFYPRANKKLQSYLGEHHLVLSEYGPESEPLKFHFPERNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGSILDGRSDGCHHLIQEGAKCVTTGADVLSEFQF

Nucleotide

• Length: 843 bp

>NTDB_id=121207 DK43_RS05325 WP_003042009.1 1098686..1099528(+) (dprA/cilB/dalA) [Streptococcus anginosus strain SA1]
ATGGATAATTTTGATATTTATAAATTAAAAAAAGCCGGCTTGACCAACCAACAGGTCATCAATGTTCTTTCGTATGCTGA
AATACAAGACAAAGAATTATCGGTAAAAGATATGGCAGTTGTTTCGGAATGCCGCAATCCTGCTCTTTTCATTGAAAAAT
ATCTGCAGCTAGATGATGATTTATTATGTCAAGAATTTGAAAAATTTCCGTCTTTTTCTATCTTGGATGATGTGTATCCT
TGGGATTTGAGCGAAATTTACAATCCACCCGTTCTACTTTTCTATAAAGGAAACTTGGATTTGTTAAAATTACCGAAAGT
AGCTGTTGTGGGAAGCCGCAATAGTAGCCGAACAGGCAGTCAATCTGTTCAAAAAATTGTTAAAGAGCTAAACAATGAGC
TAGTTATCGTAAGCGGCTTAGCGCGCGGAATTGATACATCAGCTCACATGGCAGCGTTGCAAAATGGCGGTCGAACGATT
GCCGTTATTGGAACCGGTTTAGATGTTTTTTATCCAAGAGCAAATAAAAAACTTCAATCTTATTTGGGAGAACATCACCT
TGTGCTTAGTGAATATGGTCCCGAATCAGAGCCATTGAAATTTCATTTTCCAGAGCGGAATCGCATTATTGCAGGTTTGT
GTAGAGGCGTTATTGTAGCTGAAGCCAAAATGCGCTCAGGAAGTCTAATTACTTGTGAGCGCGCAATGGAAGAAGGACGA
GATGTGTTTGCTATTCCAGGGTCAATTTTAGACGGCAGAAGTGATGGCTGTCATCATTTGATTCAAGAGGGTGCAAAGTG
CGTCACAACAGGCGCTGACGTACTTTCTGAATTCCAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-60)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	77.143	100	0.771
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	76.786	100	0.768
dprA/cilB/dalA	Streptococcus pneumoniae D39	76.786	100	0.768
dprA/cilB/dalA	Streptococcus pneumoniae R6	76.786	100	0.768
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	76.786	100	0.768
dprA/cilB/dalA	Streptococcus mitis SK321	76.429	100	0.764
dprA	Streptococcus mutans UA159	65	100	0.65
dprA	Lactococcus lactis subsp. cremoris KW2	58.214	100	0.582
dprA	Staphylococcus aureus N315	37.943	100	0.382
dprA	Staphylococcus aureus MW2	37.722	100	0.379
dprA	Legionella pneumophila strain ERS1305867	50.739	72.5	0.368
dprA	Bacillus subtilis subsp. subtilis str. 168	44.934	81.071	0.364