Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DYB47_RS06460 Genome accession   NZ_UHFV01000002
Coordinates   1287005..1287712 (-) Length   235 a.a.
NCBI ID   WP_003079776.1    Uniprot ID   G5JWH8
Organism   Streptococcus macacae NCTC 11558     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1282005..1292712
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DYB47_RS06445 (NCTC11558_01314) rnc 1283937..1284632 (-) 696 WP_003080395.1 ribonuclease III -
  DYB47_RS06450 (NCTC11558_01315) vicX 1284863..1285666 (-) 804 WP_003080272.1 MBL fold metallo-hydrolase Regulator
  DYB47_RS06455 (NCTC11558_01316) vicK 1285666..1287012 (-) 1347 WP_003081620.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DYB47_RS06460 (NCTC11558_01317) vicR 1287005..1287712 (-) 708 WP_003079776.1 response regulator YycF Regulator
  DYB47_RS06465 (NCTC11558_01318) - 1288058..1288840 (+) 783 WP_003078979.1 amino acid ABC transporter ATP-binding protein -
  DYB47_RS06470 (NCTC11558_01319) - 1288837..1289655 (+) 819 WP_003079127.1 transporter substrate-binding domain-containing protein -
  DYB47_RS06475 (NCTC11558_01320) - 1289672..1290370 (+) 699 WP_003081514.1 amino acid ABC transporter permease -
  DYB47_RS06480 (NCTC11558_01321) - 1290385..1291035 (+) 651 WP_003078567.1 amino acid ABC transporter permease -
  DYB47_RS06490 (NCTC11558_01322) endA 1291626..1292498 (-) 873 WP_003080950.1 DNA/RNA non-specific endonuclease Machinery gene

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26955.80 Da        Isoelectric Point: 4.7703

>NTDB_id=1171324 DYB47_RS06460 WP_003079776.1 1287005..1287712(-) (vicR) [Streptococcus macacae NCTC 11558]
MKKILIVDDEKPISDIIKFNLSKEGYDTITAFDGREALAKFEEENPDLIILDLMLPELDGLEVAKEIRKSSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTENIETAVAEENASGIPEIVIGELQILPDAFIAKKRGEEVEL
THREFELLHHLATHTGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=1171324 DYB47_RS06460 WP_003079776.1 1287005..1287712(-) (vicR) [Streptococcus macacae NCTC 11558]
ATGAAGAAGATTTTAATCGTTGATGATGAAAAGCCGATTTCGGATATTATCAAATTCAATCTATCCAAGGAGGGCTACGA
TACGATTACAGCTTTTGACGGTCGTGAGGCCTTAGCAAAATTTGAAGAGGAGAATCCTGATTTAATCATTCTGGATTTAA
TGCTGCCAGAGTTAGATGGTCTAGAAGTGGCAAAAGAAATCAGAAAAAGCAGCCATGTCCCTATTATCATGCTGTCTGCT
AAAGACAGCGAGTTTGATAAGGTCATCGGCCTTGAAATCGGCGCAGATGACTATGTTACAAAACCTTTTTCAAACCGAGA
GTTACTGGCACGTATCAAGGCACATCTTCGCCGTACTGAAAACATTGAAACGGCAGTAGCTGAAGAAAATGCTTCTGGTA
TACCAGAAATTGTTATTGGTGAGCTGCAGATTTTGCCAGATGCCTTTATAGCGAAAAAGCGCGGTGAAGAAGTGGAGCTA
ACCCATCGTGAATTTGAATTGCTGCATCATTTAGCGACACATACGGGTCAAGTAATGACTCGGGAGCACTTACTGGAAAC
CGTTTGGGGTTATGACTATTTTGGAGATGTGCGAACAGTTGATGTCACTGTTAGACGTTTGCGTGAAAAAATTGAAGACA
CACCGAGCCGTCCGGAGTATATTTTAACAAGACGCGGTGTGGGCTATTATATGAAATCGTATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5JWH8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

95.319

100

0.953
  micA Streptococcus pneumoniae Cp1015

78.541

99.149

0.779
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.121

98.723

0.455
  covR Streptococcus salivarius strain HSISS4

45.923

99.149

0.455
  scnR Streptococcus mutans UA159

38.034

99.574

0.379

Multiple sequence alignment