Detailed information NTG1171325

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: DYB47_RS06490
• Genome accession: NZ_UHFV01000002
• Coordinates: 1291626..1292498 (-)
• Length: 290 a.a.
• NCBI ID: WP_003080950.1
• Uniprot ID: G5JWI4
• Organism: Streptococcus macacae NCTC 11558
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1286626..1297498

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DYB47_RS06460 (NCTC11558_01317)	vicR	1287005..1287712 (-)	708	WP_003079776.1	response regulator YycF	Regulator
DYB47_RS06465 (NCTC11558_01318)	-	1288058..1288840 (+)	783	WP_003078979.1	amino acid ABC transporter ATP-binding protein	-
DYB47_RS06470 (NCTC11558_01319)	-	1288837..1289655 (+)	819	WP_003079127.1	transporter substrate-binding domain-containing protein	-
DYB47_RS06475 (NCTC11558_01320)	-	1289672..1290370 (+)	699	WP_003081514.1	amino acid ABC transporter permease	-
DYB47_RS06480 (NCTC11558_01321)	-	1290385..1291035 (+)	651	WP_003078567.1	amino acid ABC transporter permease	-
DYB47_RS06490 (NCTC11558_01322)	endA	1291626..1292498 (-)	873	WP_003080950.1	DNA/RNA non-specific endonuclease	Machinery gene
DYB47_RS06495 (NCTC11558_01323)	-	1292645..1292833 (-)	189	WP_003078679.1	DNA-directed RNA polymerase subunit beta	-
DYB47_RS06500 (NCTC11558_01324)	murA	1292833..1294107 (-)	1275	WP_003079654.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
DYB47_RS06505	-	1294170..1294406 (-)	237	WP_280523028.1	DUF1146 family protein	-
DYB47_RS06510 (NCTC11558_01325)	-	1294458..1294874 (-)	417	WP_003079306.1	F0F1 ATP synthase subunit epsilon	-
DYB47_RS06515 (NCTC11558_01326)	atpD	1294888..1296294 (-)	1407	WP_003080201.1	F0F1 ATP synthase subunit beta	-
DYB47_RS06520 (NCTC11558_01327)	-	1296498..1297379 (-)	882	WP_003081977.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 290 a.a.
• Molecular weight: 32348.41 Da
• Isoelectric Point: 10.4192

>NTDB_id=1171325 DYB47_RS06490 WP_003080950.1 1291626..1292498(-) (endA) [Streptococcus macacae NCTC 11558]
MRKKNRQQQRFLVSIAALLVLAALSYFATNDKIADGNPTKQVAQFFTDKEKAGKRHSNAFSDNQDTPNKGLADSVLTENV
KQILGNQLKWNGAGAYILNHNKTDLNAKVASIPYAVNETKIIQGRMVPTVANALLAKSTRQYRSRREMTNKETYWRPAGW
HQLHGLAGTYNHAVDRGHLLAYSLVGGLKDFDASTSNPKNIATQTAWSNQAGSDSSTGQNYYETMIRKALDSNKRVRYRV
TLIYDTNNILASGRQLEAKSSDKSLEFNVFIPNVQPGLTFDYTTGKVQKN

Nucleotide

• Length: 873 bp

>NTDB_id=1171325 DYB47_RS06490 WP_003080950.1 1291626..1292498(-) (endA) [Streptococcus macacae NCTC 11558]
ATGAGAAAAAAGAACAGACAACAGCAGCGTTTTTTAGTTTCAATAGCAGCCCTGCTTGTTTTGGCTGCTTTGTCCTATTT
TGCTACTAATGATAAGATTGCTGATGGTAATCCTACCAAACAAGTTGCCCAGTTTTTTACGGACAAAGAAAAGGCAGGAA
AAAGGCATTCGAATGCTTTTTCTGATAATCAGGATACTCCCAATAAAGGCTTAGCTGATAGTGTTCTGACAGAAAATGTC
AAGCAGATTTTGGGAAATCAGCTAAAGTGGAATGGCGCTGGTGCGTATATTTTGAATCATAATAAGACAGATTTAAATGC
TAAAGTTGCTAGTATTCCTTATGCAGTTAATGAAACAAAAATAATTCAGGGTAGGATGGTTCCTACAGTTGCTAATGCGC
TTTTGGCAAAGTCAACACGGCAGTATAGAAGCCGCAGAGAGATGACAAATAAAGAGACTTATTGGCGTCCTGCTGGTTGG
CATCAATTGCATGGTTTAGCCGGAACTTATAATCATGCTGTTGATAGGGGACATTTACTGGCTTATTCTCTTGTTGGTGG
CTTAAAAGATTTTGATGCTTCTACTAGCAATCCGAAAAATATTGCTACGCAGACAGCTTGGTCCAATCAAGCAGGAAGTG
ACAGTTCGACTGGTCAAAATTATTATGAAACAATGATTCGAAAGGCTTTGGATAGCAATAAGCGTGTCCGTTATCGGGTA
ACACTTATTTATGACACTAACAATATTTTAGCCAGCGGAAGGCAGCTGGAAGCTAAGTCTTCAGATAAAAGCCTTGAGTT
TAATGTTTTTATTCCTAATGTTCAGCCAGGTTTGACTTTTGATTATACCACAGGAAAAGTCCAAAAAAATTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (125-249)

3D structure

• AlphaFold DB: G5JWI4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	62.5	77.241	0.483
endA	Streptococcus pneumoniae D39	62.5	77.241	0.483
endA	Streptococcus pneumoniae R6	62.5	77.241	0.483
endA	Streptococcus pneumoniae TIGR4	62.5	77.241	0.483