Detailed information NTG1171323

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: DYB47_RS06455
• Genome accession: NZ_UHFV01000002
• Coordinates: 1285666..1287012 (-)
• Length: 448 a.a.
• NCBI ID: WP_003081620.1
• Uniprot ID: -
• Organism: Streptococcus macacae NCTC 11558
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1280666..1292012

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DYB47_RS06445 (NCTC11558_01314)	rnc	1283937..1284632 (-)	696	WP_003080395.1	ribonuclease III	-
DYB47_RS06450 (NCTC11558_01315)	vicX	1284863..1285666 (-)	804	WP_003080272.1	MBL fold metallo-hydrolase	Regulator
DYB47_RS06455 (NCTC11558_01316)	vicK	1285666..1287012 (-)	1347	WP_003081620.1	cell wall metabolism sensor histidine kinase VicK	Regulator
DYB47_RS06460 (NCTC11558_01317)	vicR	1287005..1287712 (-)	708	WP_003079776.1	response regulator YycF	Regulator
DYB47_RS06465 (NCTC11558_01318)	-	1288058..1288840 (+)	783	WP_003078979.1	amino acid ABC transporter ATP-binding protein	-
DYB47_RS06470 (NCTC11558_01319)	-	1288837..1289655 (+)	819	WP_003079127.1	transporter substrate-binding domain-containing protein	-
DYB47_RS06475 (NCTC11558_01320)	-	1289672..1290370 (+)	699	WP_003081514.1	amino acid ABC transporter permease	-
DYB47_RS06480 (NCTC11558_01321)	-	1290385..1291035 (+)	651	WP_003078567.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 448 a.a.
• Molecular weight: 51505.00 Da
• Isoelectric Point: 4.3157

>NTDB_id=1171323 DYB47_RS06455 WP_003081620.1 1285666..1287012(-) (vicK) [Streptococcus macacae NCTC 11558]
MTNIFESTPLLLRLLLASLIILLFLYFIFLNYREYKNTNQIKLLNTKVRSLITGEYTDKLEMKSNPELSDLVSNINDLSE
VFRLTHENLEQEKNRLTSILSYMTDGVLATDRSGKITMINETAQKQLNLSREEALEYNILDILEDDSYTYNDLITKTPEI
TLNRRDENDEFITLRIRFALNRRESGFISGLIAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALTE
SVAPSFIKVSLDETNRMMRMISDLLSLSRIDNQTSHLDVELTNFTAYMNYILDRFDQISLQSESKVYEIVRDYSEDSVWI
EIDTDKMTQVIDNILNNAIKYSPDGGTITVTIQTTDTQLILSISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGLGL
AIAKEIVKQHHGYIWASSDEGEGSTFTIVLPYENDNTMDEEWEEDEDI

Nucleotide

• Length: 1347 bp

>NTDB_id=1171323 DYB47_RS06455 WP_003081620.1 1285666..1287012(-) (vicK) [Streptococcus macacae NCTC 11558]
ATGACTAATATATTTGAATCCACTCCCTTGCTTTTAAGGCTTTTATTAGCAAGTCTTATTATTCTGCTGTTTCTTTACTT
TATCTTTTTAAATTATCGTGAATATAAAAACACCAATCAGATTAAATTGTTAAATACTAAAGTGCGTTCTTTGATTACCG
GAGAATATACCGATAAACTCGAAATGAAGTCTAATCCTGAACTGTCTGATTTGGTTAGTAACATTAATGATTTGTCTGAA
GTTTTCCGTTTGACGCATGAAAATTTAGAACAGGAAAAAAACCGTCTGACAAGTATCTTATCGTATATGACAGACGGTGT
TTTGGCTACTGATCGCAGCGGCAAAATCACTATGATTAATGAAACTGCTCAAAAACAACTTAATTTAAGCCGCGAAGAAG
CCTTGGAATATAATATTCTTGATATTTTAGAAGATGATAGTTATACTTATAATGATTTAATTACAAAGACCCCAGAGATT
ACTCTGAATCGCCGCGATGAAAACGATGAGTTTATCACTTTGCGTATTCGTTTTGCTTTAAACCGCCGTGAAAGCGGCTT
TATTTCAGGATTGATTGCAGTCCTGCATGATGCAACGGAACAGGAAAAAGAAGAGCGTGAACGTCGTCTCTTTGTTTCCA
ATGTTAGCCATGAGTTGCGTACGCCGCTGACTTCAGTGAAGTCTTATTTGGAGGCCTTGGATGATGGTGCTTTAACAGAA
TCTGTCGCGCCAAGCTTTATCAAAGTATCATTAGATGAGACCAATCGTATGATGCGTATGATTTCAGACTTGCTGAGCTT
ATCTCGCATTGATAATCAAACTTCGCATTTAGATGTAGAGCTGACTAATTTTACAGCTTATATGAATTATATTCTTGATC
GATTTGATCAAATCAGTCTGCAGTCTGAAAGCAAAGTGTATGAGATTGTTAGGGATTACTCTGAGGATTCTGTTTGGATT
GAGATTGATACGGATAAAATGACACAAGTTATTGATAATATTTTAAATAATGCCATCAAATATTCTCCCGACGGCGGGAC
AATCACGGTAACTATCCAGACAACAGATACTCAATTAATTCTTTCAATTTCAGATGAAGGTCTTGGAATTCCCAAAAAAG
ATTTACCGCTTATTTTTGATCGCTTCTACCGTGTTGATAAAGCAAGAAGCAGAGCGCAAGGCGGTACGGGTTTAGGTCTT
GCGATAGCTAAAGAAATCGTTAAGCAGCATCATGGTTACATCTGGGCCAGCAGTGATGAAGGGGAAGGATCAACTTTTAC
AATTGTTCTGCCTTATGAAAATGATAATACAATGGATGAAGAATGGGAGGAAGATGAAGACATATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (323-433)

• His Kinase A (phospho-acceptor) domain (HisKA) (208-272)

• PAS fold (PAS) (96-173)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	88.33	97.545	0.862
micB	Streptococcus pneumoniae Cp1015	67.78	93.527	0.634