Detailed information NTG1171316

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DYB47_RS04890
• Genome accession: NZ_UHFV01000002
• Coordinates: 929548..930384 (+)
• Length: 278 a.a.
• NCBI ID: WP_003081306.1
• Uniprot ID: G5JU84
• Organism: Streptococcus macacae NCTC 11558
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 924548..935384

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DYB47_RS04860 (NCTC11558_00982)	-	925286..925624 (+)	339	WP_003080675.1	ATP cone domain-containing protein	-
DYB47_RS04865 (NCTC11558_00983)	-	925801..926769 (+)	969	WP_003080437.1	hypothetical protein	-
DYB47_RS04870 (NCTC11558_00984)	ylqF	926891..927742 (+)	852	WP_003082274.1	ribosome biogenesis GTPase YlqF	-
DYB47_RS04875 (NCTC11558_00985)	-	927729..928502 (+)	774	WP_003079953.1	ribonuclease HII	-
DYB47_RS04880 (NCTC11558_00986)	-	928604..928870 (+)	267	WP_003080622.1	hypothetical protein	-
DYB47_RS04885 (NCTC11558_00987)	-	928874..929422 (+)	549	WP_003079462.1	sugar O-acetyltransferase	-
DYB47_RS04890 (NCTC11558_00988)	dprA	929548..930384 (+)	837	WP_003081306.1	DNA-processing protein DprA	Machinery gene
DYB47_RS04895 (NCTC11558_00989)	topA	930486..932600 (+)	2115	WP_003081026.1	type I DNA topoisomerase	-
DYB47_RS04900 (NCTC11558_00990)	trmFO	932885..934219 (+)	1335	WP_003080974.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30952.69 Da
• Isoelectric Point: 9.5754

>NTDB_id=1171316 DYB47_RS04890 WP_003081306.1 929548..930384(+) (dprA) [Streptococcus macacae NCTC 11558]
MDNFQLFKLKKAGLTNLNILKIIEYQKTKKKSLSLRDMAVVSGCREPLLFMEQYKNLNSSVLRKEFNRFSSLSIFDKDYP
LELKNIYNPPALLFYKGNIDLLQSKKLAIVGSRSSSQNGIDAVKKIVQELGNRFVIVSGLARGIDTSAHLAVLRNGGSSI
AVIGTGLDMYYPKENKQLQDYIAHNHLLLSEYGPGSRPLKYHFPERNRIIAGLSQGVVVAEAKLRSGSLITSERALEEGR
DVYAIPGNILDGYSDGCHHLIQEGAKCITSGLDILNEY

Nucleotide

• Length: 837 bp

>NTDB_id=1171316 DYB47_RS04890 WP_003081306.1 929548..930384(+) (dprA) [Streptococcus macacae NCTC 11558]
ATGGATAATTTTCAACTATTTAAACTAAAAAAAGCAGGACTGACAAATCTAAATATTTTAAAAATTATAGAATATCAAAA
AACAAAGAAAAAATCTTTGTCTCTTCGTGATATGGCTGTTGTTTCCGGCTGTCGGGAACCTCTACTTTTTATGGAACAGT
ATAAAAACTTGAATAGCAGCGTATTGCGAAAGGAATTTAATCGTTTTTCCTCTCTGTCTATTTTTGATAAAGATTACCCA
TTGGAGCTAAAAAATATCTATAATCCTCCAGCGCTTTTATTTTATAAAGGTAATATTGATCTTTTACAAAGCAAAAAATT
AGCAATTGTTGGCTCTAGATCTTCTAGCCAAAACGGTATAGATGCGGTTAAAAAGATTGTACAAGAATTGGGAAACCGGT
TTGTTATTGTTAGTGGTTTGGCACGTGGAATTGATACAAGTGCTCATTTAGCTGTGTTAAGAAATGGAGGATCTAGCATT
GCTGTTATCGGTACAGGACTAGATATGTACTATCCTAAAGAAAATAAACAATTACAAGATTATATTGCTCACAATCATCT
CCTTTTATCAGAATATGGACCAGGCAGCAGACCCTTAAAATATCATTTTCCAGAACGCAATAGAATCATCGCAGGGCTGT
CCCAAGGAGTTGTTGTTGCAGAAGCTAAACTGCGTTCAGGAAGCTTGATTACTTCTGAACGTGCCTTAGAGGAAGGAAGA
GATGTCTATGCAATTCCTGGAAATATTTTAGATGGCTACTCAGATGGCTGTCACCATTTGATACAAGAGGGAGCAAAATG
CATAACTTCGGGTCTTGATATCTTAAATGAATATTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (69-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-60)

3D structure

• AlphaFold DB: G5JU84

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	76.978	100	0.77
dprA/cilB/dalA	Streptococcus mitis SK321	63.309	100	0.633
dprA/cilB/dalA	Streptococcus pneumoniae D39	62.95	100	0.63
dprA/cilB/dalA	Streptococcus pneumoniae R6	62.95	100	0.63
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	62.95	100	0.63
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	62.95	100	0.63
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.23	100	0.622
dprA	Lactococcus lactis subsp. cremoris KW2	58.993	100	0.59
dprA	Legionella pneumophila strain ERS1305867	44.958	85.612	0.385
dprA	Bacillus subtilis subsp. subtilis str. 168	48.341	75.899	0.367
dprA	Latilactobacillus sakei subsp. sakei 23K	38.996	93.165	0.363