Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACLV7D_RS01645 Genome accession   NZ_OZ217345
Coordinates   318651..319907 (+) Length   418 a.a.
NCBI ID   WP_218764296.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis F22     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 313651..324907
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7D_RS01620 (SMIF22_03120) comM 314237..314857 (+) 621 WP_050222261.1 hypothetical protein Regulator
  ACLV7D_RS01625 (SMIF22_03130) - 315242..316408 (-) 1167 WP_218764773.1 IS30 family transposase -
  ACLV7D_RS01630 (SMIF22_03140) tsaE 316592..317035 (+) 444 WP_173282564.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  ACLV7D_RS01635 (SMIF22_03150) - 317025..317543 (+) 519 WP_173282565.1 GNAT family N-acetyltransferase -
  ACLV7D_RS01640 (SMIF22_03160) brpA 317551..318567 (+) 1017 WP_218764297.1 biofilm formation/cell division transcriptional regulator BrpA -
  ACLV7D_RS01645 (SMIF22_03170) cinA 318651..319907 (+) 1257 WP_218764296.1 competence/damage-inducible protein A Machinery gene
  ACLV7D_RS01650 (SMIF22_03180) recA 319962..321128 (+) 1167 WP_050234077.1 recombinase RecA Machinery gene
  ACLV7D_RS01655 (SMIF22_03190) - 321243..322613 (+) 1371 WP_218764295.1 MATE family efflux transporter -
  ACLV7D_RS01660 (SMIF22_03200) - 322982..323932 (+) 951 WP_218764294.1 N-acetylmuramoyl-L-alanine amidase family protein -
  ACLV7D_RS01665 (SMIF22_03210) - 324303..324647 (+) 345 WP_050086717.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45053.25 Da        Isoelectric Point: 4.6678

>NTDB_id=1170345 ACLV7D_RS01645 WP_218764296.1 318651..319907(+) (cinA) [Streptococcus mitis isolate S. mitis F22]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKELVFDSQAQEKLDVFFAQRPDYARTPNNERQAQIVEGATPLPNETGLAVGGILEVNGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIANQTDPTLAPYAKTGEVTLRLSTKASSQEEANQVLDILEHQI
LNRQTFEGLSLRDLCYGYGEESSLASIVVEELKKQGKTITAAESLTAGLFQANVADFSGASSIFKGGFVTYSLEEKSKML
DIPDKDLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPAGTVFIGLAQEHGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1170345 ACLV7D_RS01645 WP_218764296.1 318651..319907(+) (cinA) [Streptococcus mitis isolate S. mitis F22]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCAGA
AAAACTAGCTGAGATTGGGGTAGATGTTTATTTTCAGACGGCTGTAGGAGACAATGAAGCTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGTAGTCTGGTGATTTTGACAGGCGGTTTAGGGCCAACTGAGGATGATTTGACCAAACAAACT
CTGGCTAAATTTTTAGGGAAAGAATTAGTCTTCGATTCTCAGGCTCAGGAGAAGTTAGATGTCTTTTTTGCCCAGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGACTCCACTGCCAAACGAAACAGGGT
TGGCTGTGGGAGGAATATTAGAAGTAAACGGAGTGACCTACGTCGTCCTTCCAGGTCCACCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTTTTTGGAATTGGCGA
AAGTCAGTTGGTTACGATTTTGGCTGATTTGATTGCTAATCAAACAGATCCTACCTTGGCACCTTATGCCAAGACAGGAG
AGGTAACCTTGCGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGTGCTGGATATTTTGGAACATCAAATC
TTGAATCGCCAGACCTTTGAAGGACTTTCTTTACGAGACCTTTGTTATGGTTATGGGGAAGAGTCCAGCTTGGCCAGCAT
TGTGGTAGAAGAACTGAAAAAGCAAGGGAAAACCATCACAGCAGCAGAGAGTTTAACGGCAGGGCTTTTCCAAGCCAATG
TGGCGGATTTTTCTGGTGCTTCCAGTATATTTAAGGGTGGTTTTGTGACCTATAGCCTGGAGGAAAAATCAAAGATGTTG
GATATTCCTGACAAGGATTTGGAAGAACACGGTGTGGTATCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
TAAGACCCAGTCAGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGCTGGGACAG
TCTTTATAGGCTTGGCACAGGAGCATGGAACAGAGGTCATCAAGGTGAATATTGGAGGCAGAAGTCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

97.368

100

0.974
  cinA Streptococcus mitis NCTC 12261

95.694

100

0.957
  cinA Streptococcus pneumoniae TIGR4

93.062

100

0.931
  cinA Streptococcus pneumoniae Rx1

92.823

100

0.928
  cinA Streptococcus pneumoniae R6

92.823

100

0.928
  cinA Streptococcus pneumoniae D39

92.584

100

0.926
  cinA Streptococcus mutans UA159

72.727

100

0.727
  cinA Streptococcus suis isolate S10

54.567

99.522

0.543
  cinA Bacillus subtilis subsp. subtilis str. 168

45.694

100

0.457

Multiple sequence alignment