Detailed information NTG1170286

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: ACLV7A_RS04620
• Genome accession: NZ_OZ217344
• Coordinates: 928870..929718 (+)
• Length: 282 a.a.
• NCBI ID: WP_411863723.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis E22
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 923870..934718

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7A_RS04595 (SMIE22_09050)	-	924593..925300 (+)	708	WP_000638495.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
ACLV7A_RS04600 (SMIE22_09060)	-	925305..926327 (+)	1023	WP_411863720.1	ribitol-5-phosphate dehydrogenase	-
ACLV7A_RS04605 (SMIE22_09070)	licA	926344..927213 (+)	870	WP_411863721.1	choline kinase LicA	-
ACLV7A_RS04610 (SMIE22_09080)	-	927203..928081 (+)	879	WP_164226567.1	DMT family transporter	-
ACLV7A_RS04615 (SMIE22_09090)	-	928093..928782 (+)	690	WP_411863722.1	sugar phosphate nucleotidyltransferase	-
ACLV7A_RS04620 (SMIE22_09100)	dprA/cilB/dalA	928870..929718 (+)	849	WP_411863723.1	DNA-processing protein DprA	Machinery gene
ACLV7A_RS04625 (SMIE22_09110)	-	930492..931535 (+)	1044	WP_411863724.1	TIGR00341 family protein	-
ACLV7A_RS04630 (SMIE22_09120)	topA	931702..933789 (+)	2088	WP_057487767.1	type I DNA topoisomerase	-
ACLV7A_RS04635	-	933888..934046 (+)	159	WP_050492352.1	hypothetical protein	-
ACLV7A_RS04640 (SMIE22_09130)	-	934091..934450 (+)	360	WP_050083961.1	YbaN family protein	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31163.79 Da
• Isoelectric Point: 5.2107

>NTDB_id=1170286 ACLV7A_RS04620 WP_411863723.1 928870..929718(+) (dprA/cilB/dalA) [Streptococcus mitis isolate S. mitis E22]
MKITNYEIYKLKKSGLSNQQILNVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDKHLEKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKTNKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVLVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=1170286 ACLV7A_RS04620 WP_411863723.1 928870..929718(+) (dprA/cilB/dalA) [Streptococcus mitis isolate S. mitis E22]
ATGAAAATCACAAACTATGAAATCTATAAGTTGAAAAAATCAGGTTTGAGCAATCAACAGATTTTAAATGTTCTAGAATA
CGGTGAAAATGTCGATCAAGAACTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGAAATCCAGCTGTTTTTATGG
AACGTTATTTTCAGATAGACGATAAGCATTTGGAGAAGGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGACGATTGT
TATCCTTGGGATTTAAGTGAAATATACGATGCTCCTGTGCTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTTCC
AAAAGTCGCGGTTGTGGGTAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAGGGCTTGGAAA
ATGAACTGGTTATCGTCAGTGGATTAGCCAAGGGAATAGACACAGCAGCTCATATGGCAGCCCTGCAAAATGGCGGAAAA
ACTATTGCAGTGATTGGAACAGGATTGGATGTGTTTTATCCTAAAACCAATAAACGCTTGCAAGACTATATCGGCAATGA
CCATCTGGTTCTAAGTGAATATGGACCTGGTGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGCTTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACCTGTGAGCGAGCAATGGAAGAA
GGGCGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGTGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCAGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	97.872	100	0.979
dprA/cilB/dalA	Streptococcus pneumoniae D39	97.872	100	0.979
dprA/cilB/dalA	Streptococcus pneumoniae R6	97.872	100	0.979
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	97.872	100	0.979
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	97.518	100	0.975
dprA/cilB/dalA	Streptococcus mitis SK321	96.454	100	0.965
dprA	Streptococcus mutans UA159	63.571	99.291	0.631
dprA	Lactococcus lactis subsp. cremoris KW2	55.357	99.291	0.55
dprA	Staphylococcus aureus N315	38.516	100	0.387
dprA	Staphylococcus aureus MW2	38.516	100	0.387
dprA	Haemophilus influenzae Rd KW20	38.951	94.681	0.369