Detailed information NTG1170121

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: ACLV65_RS04580
• Genome accession: NZ_OZ217342
• Coordinates: 898556..899404 (+)
• Length: 282 a.a.
• NCBI ID: WP_411864661.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis B22
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 893556..904404

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV65_RS04555 (SMIB22_08900)	-	894279..894986 (+)	708	WP_000638489.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
ACLV65_RS04560 (SMIB22_08910)	-	894991..896013 (+)	1023	WP_050389974.1	ribitol-5-phosphate dehydrogenase	-
ACLV65_RS04565 (SMIB22_08920)	licA	896030..896899 (+)	870	WP_411864659.1	choline kinase LicA	-
ACLV65_RS04570 (SMIB22_08930)	-	896889..897767 (+)	879	WP_411864660.1	DMT family transporter	-
ACLV65_RS04575 (SMIB22_08940)	-	897779..898468 (+)	690	WP_000643965.1	sugar phosphate nucleotidyltransferase	-
ACLV65_RS04580 (SMIB22_08950)	dprA/cilB/dalA	898556..899404 (+)	849	WP_411864661.1	DNA-processing protein DprA	Machinery gene
ACLV65_RS04585 (SMIB22_08960)	-	900140..901183 (+)	1044	WP_411864662.1	TIGR00341 family protein	-
ACLV65_RS04590 (SMIB22_08970)	topA	901349..903436 (+)	2088	WP_411864663.1	type I DNA topoisomerase	-
ACLV65_RS04595 (SMIB22_08980)	-	903647..904006 (+)	360	WP_411864664.1	YbaN family protein	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31162.84 Da
• Isoelectric Point: 5.2232

>NTDB_id=1170121 ACLV65_RS04580 WP_411864661.1 898556..899404(+) (dprA/cilB/dalA) [Streptococcus mitis isolate S. mitis B22]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGGIADISGCRNPAVFMERYFQIDDEHLEKEFKKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPDSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=1170121 ACLV65_RS04580 WP_411864661.1 898556..899404(+) (dprA/cilB/dalA) [Streptococcus mitis isolate S. mitis B22]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTACTAGAATA
CGGTGAAAATGTTGATCAAGAACTGTTGTTAGGTGGTATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGAGCATTTGGAGAAGGAGTTTAAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TACCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAAGGAAATCTTGACCTCTTGAAATTTCC
TAAGGTAGCGGTTGTGGGTAGTCGCGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAGGGCTTGGAAA
ATGAACTGGTTATCGTCAGTGGATTAGCCAAGGGTATCGATACAGCAGCTCATATGGCAGCTCTTCAAAATGGTGGAAAA
ACCATTGCAGTGATTGGAACAGGTCTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTATATCGGAAATGA
TCATCTGGTTCTCAGTGAATATGGACCTGGAGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAACCGCATCATTGCTG
GACTTTGTCGAGGTGTGATTGTAGCAGAGGCTAAGATGCGCTCAGGTAGTCTCATTACCTGTGAGCGAGCAATGGAGGAA
GGGCGAGATGTCTTTGCTATTCCTGATAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAGGAAGGTGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCAGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	98.227	100	0.982
dprA/cilB/dalA	Streptococcus pneumoniae D39	98.227	100	0.982
dprA/cilB/dalA	Streptococcus pneumoniae R6	98.227	100	0.982
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	98.227	100	0.982
dprA/cilB/dalA	Streptococcus mitis SK321	97.518	100	0.975
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	97.518	100	0.975
dprA	Streptococcus mutans UA159	62.5	99.291	0.621
dprA	Lactococcus lactis subsp. cremoris KW2	55.714	99.291	0.553
dprA	Acinetobacter baumannii D1279779	36.519	100	0.379
dprA	Acinetobacter baumannii strain A118	36.177	100	0.376