Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   ACLV7H_RS07095 Genome accession   NZ_OZ217340
Coordinates   1358071..1358661 (-) Length   196 a.a.
NCBI ID   WP_045590796.1    Uniprot ID   A0A0F2D2I9
Organism   Streptococcus oralis isolate S. oralis A22     
Function   degradation of ComX; degradation of ComW (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1349276..1360021 1358071..1358661 within 0


Gene organization within MGE regions


Location: 1349276..1360021
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7H_RS07045 (SORA22_14180) ftsX 1349276..1350202 (-) 927 WP_411866744.1 permease-like cell division protein FtsX -
  ACLV7H_RS07050 (SORA22_14190) ftsE 1350195..1350887 (-) 693 WP_000022272.1 cell division ATP-binding protein FtsE -
  ACLV7H_RS07060 (SORA22_14210) - 1352111..1352767 (-) 657 WP_045590807.1 CBS domain-containing protein -
  ACLV7H_RS07065 (SORA22_14220) - 1353052..1353762 (-) 711 WP_045590805.1 ABC transporter ATP-binding protein -
  ACLV7H_RS07070 (SORA22_14230) - 1353762..1354526 (-) 765 WP_045590804.1 ABC transporter ATP-binding protein -
  ACLV7H_RS07075 (SORA22_14240) - 1354526..1355482 (-) 957 WP_045590803.1 branched-chain amino acid ABC transporter permease -
  ACLV7H_RS07080 (SORA22_14250) - 1355486..1356355 (-) 870 WP_000941413.1 branched-chain amino acid ABC transporter permease -
  ACLV7H_RS07085 (SORA22_14260) - 1356474..1357634 (-) 1161 WP_045590800.1 ABC transporter substrate-binding protein -
  ACLV7H_RS07090 (SORA22_14270) - 1357723..1357992 (-) 270 WP_411866746.1 YlbG family protein -
  ACLV7H_RS07095 (SORA22_14280) clpP 1358071..1358661 (-) 591 WP_045590796.1 ATP-dependent Clp protease proteolytic subunit ClpP Regulator
  ACLV7H_RS07100 (SORA22_14290) upp 1358836..1359465 (-) 630 WP_000515974.1 uracil phosphoribosyltransferase -
  ACLV7H_RS07105 (SORA22_14300) - 1359554..1360021 (-) 468 WP_411866747.1 deoxycytidylate deaminase -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21356.39 Da        Isoelectric Point: 4.4829

>NTDB_id=1169969 ACLV7H_RS07095 WP_045590796.1 1358071..1358661(-) (clpP) [Streptococcus oralis isolate S. oralis A22]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNIANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRKILEQILADNSGK
SVEQIHADAERDYWMSAQETLEYGFIDEIMANNSLS

Nucleotide


Download         Length: 591 bp        

>NTDB_id=1169969 ACLV7H_RS07095 WP_045590796.1 1358071..1358661(-) (clpP) [Streptococcus oralis isolate S. oralis A22]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTATGACATATACTCTCGTCTTCTGAAAGACCGCAT
CATCATGCTAACAGGTCCAGTTGAAGACAACATAGCCAACTCCGTTATCGCCCAGTTGCTCTTCTTGGATGCCCAAGACA
GCACAAAAGATATTTACCTTTATGTCAACACACCTGGAGGATCTGTTTCAGCTGGTTTGGCAATCGTTGATACCATGAAC
TTTATTAAAGCAGATGTCCAAACAATCGTTATGGGAATGGCTGCATCCATGGGGACTGTCATTGCATCAAGTGGCGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCGGAGTACATGATTCACCAACCAATGGGTGGAACAGGTGGTGGTACCCAACAAA
CCGATATGGCAATCGCCGCAGAGCACTTGCTCAAAACTCGTAAGATTTTGGAGCAAATCCTTGCAGATAACTCTGGTAAA
TCAGTCGAGCAAATTCATGCAGATGCGGAACGTGATTACTGGATGAGTGCCCAAGAAACACTTGAATATGGCTTTATTGA
TGAAATCATGGCCAACAATTCGTTAAGCTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F2D2I9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pneumoniae Rx1

94.388

100

0.944
  clpP Streptococcus pneumoniae D39

94.388

100

0.944
  clpP Streptococcus pneumoniae R6

94.388

100

0.944
  clpP Streptococcus pneumoniae TIGR4

94.388

100

0.944
  clpP Streptococcus pyogenes MGAS315

91.795

99.49

0.913
  clpP Streptococcus pyogenes JRS4

91.795

99.49

0.913
  clpP Streptococcus thermophilus LMD-9

90.769

99.49

0.903
  clpP Streptococcus thermophilus LMG 18311

90.769

99.49

0.903
  clpP Streptococcus mutans UA159

88.205

99.49

0.878
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

87.179

99.49

0.867
  clpP Lactococcus lactis subsp. cremoris KW2

86.667

99.49

0.862
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.549

98.469

0.577
  clpP Bacillus subtilis subsp. subtilis str. 168

57.292

97.959

0.561

Multiple sequence alignment