Detailed information NTG1159688

Bioinformatically predicted

Overview

• Name: comYA
• Type: Machinery gene
• Locus tag: OWO33_RS01125
• Genome accession: NZ_OX461090
• Coordinates: 198406..199377 (+)
• Length: 323 a.a.
• NCBI ID: WP_000250805.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae isolate MRI Z2-336
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 193406..204377

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OWO33_RS01115	rpoC	194113..197763 (+)	3651	WP_000228729.1	DNA-directed RNA polymerase subunit beta'	-
OWO33_RS01120	-	197877..198242 (+)	366	WP_000285373.1	DUF1033 family protein	-
OWO33_RS01125	comYA	198406..199377 (+)	972	WP_000250805.1	competence type IV pilus ATPase ComGA	Machinery gene
OWO33_RS01130	comYB	199271..200314 (+)	1044	WP_223295889.1	competence type IV pilus assembly protein ComGB	Machinery gene
OWO33_RS01135	-	200391..201836 (-)	1446	WP_000633501.1	recombinase family protein	-
OWO33_RS01140	-	201960..202487 (-)	528	WP_000734161.1	hypothetical protein	-
OWO33_RS01145	-	202504..203247 (-)	744	WP_001260003.1	S24 family peptidase	-
OWO33_RS01150	-	203429..203668 (+)	240	WP_000217789.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 323 a.a.
• Molecular weight: 36801.32 Da
• Isoelectric Point: 6.8469

>NTDB_id=1159688 OWO33_RS01125 WP_000250805.1 198406..199377(+) (comYA) [Streptococcus agalactiae isolate MRI Z2-336]
MVQSLAKQVIHQAVEVNAQDIYIIPKGDCYELYMRIDDERRFIDVFEFNRMASLISHFKFVAGMNVGEKRRSQLGSCDYE
LSEGRLVSLRLSSVGDYRGQESLVIRILYSGHQDLKYWFDNIKQMKEVLGIRGLYLFSGPVGSGKTTLMYQLASEVFKNK
QIITIEDPVEIKNDKMLQLQLNEDIGMTYDALIKLSLRHRPDILIIGEIRDQATARAVIRASLTGVMVFSTIHAKSIPGV
YDRLIELGVNYQELENSLKLIAYQRLIGGGSLIDFETGNFKKHSSDKWNRQVDILAEEGHISKKQAQVEKIIPQETTESS
PTF

Nucleotide

• Length: 972 bp

>NTDB_id=1159688 OWO33_RS01125 WP_000250805.1 198406..199377(+) (comYA) [Streptococcus agalactiae isolate MRI Z2-336]
ATGGTTCAATCATTAGCAAAGCAAGTCATTCATCAGGCAGTAGAAGTAAATGCTCAAGATATTTATATCATTCCCAAAGG
TGATTGTTATGAACTCTATATGCGTATTGATGATGAAAGGCGGTTTATTGATGTTTTTGAGTTTAATAGGATGGCTAGTC
TTATTAGTCACTTTAAATTTGTGGCAGGCATGAACGTTGGAGAAAAAAGACGAAGTCAATTAGGTTCTTGTGACTATGAA
CTGTCAGAGGGAAGACTGGTTTCATTACGACTATCGAGTGTGGGAGATTATCGTGGTCAAGAATCTTTAGTTATTCGTAT
TTTGTATTCAGGTCATCAGGACTTAAAATATTGGTTTGATAATATAAAGCAAATGAAGGAAGTACTGGGTATAAGAGGGC
TATATCTTTTTTCCGGCCCTGTGGGGAGTGGTAAAACAACTCTCATGTATCAATTAGCTTCAGAAGTATTTAAAAATAAG
CAAATTATCACGATTGAAGATCCGGTAGAAATCAAGAATGACAAGATGTTACAACTCCAATTGAATGAGGATATTGGAAT
GACTTATGATGCTTTAATCAAACTGTCTTTACGGCATCGTCCAGATATTTTAATTATCGGAGAGATTAGAGATCAAGCGA
CGGCCCGTGCTGTTATTCGTGCAAGTTTAACGGGAGTGATGGTTTTTTCTACTATTCATGCTAAAAGTATTCCCGGAGTC
TATGATAGGCTTATAGAATTAGGGGTTAACTATCAAGAGTTAGAAAATAGTCTAAAATTAATAGCATATCAACGTTTAAT
TGGAGGAGGAAGCCTAATTGACTTTGAGACAGGTAATTTTAAAAAACACTCATCAGACAAGTGGAATAGACAAGTGGATA
TCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAAACAACGGAAAGTAGT
CCAACTTTTTAA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (8-267)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYA	Streptococcus mutans UA159	68.81	96.285	0.663
comYA	Streptococcus mutans UA140	68.81	96.285	0.663
comYA	Streptococcus gordonii str. Challis substr. CH1	63.636	98.762	0.628
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	62.701	96.285	0.604
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	61.736	96.285	0.594
comGA/cglA/cilD	Streptococcus pneumoniae D39	61.736	96.285	0.594
comGA/cglA/cilD	Streptococcus pneumoniae R6	61.736	96.285	0.594
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	61.736	96.285	0.594
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	61.935	95.975	0.594
comGA	Lactococcus lactis subsp. cremoris KW2	50.621	99.69	0.505