Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   QOR54_RS01155 Genome accession   NZ_OX460968
Coordinates   199851..200180 (+) Length   109 a.a.
NCBI ID   WP_000793380.1    Uniprot ID   A0A0E1EKJ1
Organism   Streptococcus agalactiae isolate MRI Z2-342     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 194851..205180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QOR54_RS01140 - 197408..197773 (+) 366 WP_000285373.1 DUF1033 family protein -
  QOR54_RS01145 comYA 197946..198917 (+) 972 WP_000250805.1 competence type IV pilus ATPase ComGA Machinery gene
  QOR54_RS01150 comYB 198811..199854 (+) 1044 WP_223295889.1 competence type IV pilus assembly protein ComGB Machinery gene
  QOR54_RS01155 comGC/cglC 199851..200180 (+) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  QOR54_RS01160 comYD 200155..200568 (+) 414 WP_000244261.1 competence type IV pilus minor pilin ComGD Machinery gene
  QOR54_RS01165 comGE 200540..200839 (+) 300 WP_000234804.1 competence type IV pilus minor pilin ComGE -
  QOR54_RS01170 comGF 200793..201254 (+) 462 WP_001874812.1 competence type IV pilus minor pilin ComGF -
  QOR54_RS01175 comGG 201232..201603 (+) 372 WP_000601104.1 competence type IV pilus minor pilin ComGG -
  QOR54_RS01180 comYH 201718..202692 (+) 975 WP_001008574.1 N-6 DNA methylase Machinery gene
  QOR54_RS01185 - 202724..203917 (+) 1194 WP_000047534.1 acetate kinase -
  QOR54_RS01190 - 204069..204275 (+) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -
  QOR54_RS01195 - 204334..204471 (+) 138 WP_001865900.1 hypothetical protein -
  QOR54_RS01200 - 204512..204967 (+) 456 WP_000905673.1 hypothetical protein -

Sequence


Protein


Download         Length: 109 a.a.        Molecular weight: 12129.27 Da        Isoelectric Point: 10.0311

>NTDB_id=1159366 QOR54_RS01155 WP_000793380.1 199851..200180(+) (comGC/cglC) [Streptococcus agalactiae isolate MRI Z2-342]
MKNLLLKCKDKKVKAFTLLEMLVVLIIISVLLLLFVPNLSKQKESVTRTGNAAVVKVVESQAELFELQETGRKASLSTLK
SGGYITEKQEKAYLDYYKDSSNGSQKISS

Nucleotide


Download         Length: 330 bp        

>NTDB_id=1159366 QOR54_RS01155 WP_000793380.1 199851..200180(+) (comGC/cglC) [Streptococcus agalactiae isolate MRI Z2-342]
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAAATGTTAGTTGTTTTGATCAT
TATTTCGGTCTTGTTGTTATTGTTTGTACCCAATTTATCAAAACAAAAGGAAAGTGTCACAAGAACTGGAAATGCCGCTG
TTGTCAAGGTTGTAGAAAGTCAAGCCGAACTTTTTGAACTGCAAGAAACAGGTAGAAAAGCTAGTTTATCCACTCTAAAA
TCTGGAGGATATATTACTGAAAAGCAAGAAAAAGCCTATTTAGATTATTATAAAGACAGTTCCAATGGTTCTCAGAAAAT
TTCAAGTTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0E1EKJ1

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

60.55

100

0.606

  comGC/cglC Streptococcus mitis SK321

59.633

100

0.596

  comYC Streptococcus gordonii str. Challis substr. CH1

61.165

94.495

0.578

  comGC/cglC Streptococcus pneumoniae TIGR4

57.798

100

0.578

  comGC/cglC Streptococcus pneumoniae R6

57.798

100

0.578

  comGC/cglC Streptococcus pneumoniae Rx1

57.798

100

0.578

  comGC/cglC Streptococcus pneumoniae D39

57.798

100

0.578

  comYC Streptococcus mutans UA159

55.238

96.33

0.532

  comYC Streptococcus mutans UA140

55.238

96.33

0.532

  comGC Lactococcus lactis subsp. cremoris KW2

63.043

84.404

0.532

  comYC Streptococcus suis isolate S10

65.854

75.229

0.495


Multiple sequence alignment