Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   QOR61_RS01135 Genome accession   NZ_OX460960
Coordinates   196308..196637 (+) Length   109 a.a.
NCBI ID   WP_000793380.1    Uniprot ID   A0A0E1EKJ1
Organism   Streptococcus agalactiae isolate MRI Z2-299     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 191308..201637
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QOR61_RS01115 - 192302..192667 (+) 366 WP_000285374.1 DUF1033 family protein -
  QOR61_RS01120 - 192897..194357 (+) 1461 WP_000468685.1 IS1182-like element IS1563 family transposase -
  QOR61_RS01125 comYA 194403..195374 (+) 972 WP_000250798.1 competence type IV pilus ATPase ComGA Machinery gene
  QOR61_RS01130 comYB 195268..196311 (+) 1044 WP_283572579.1 competence type IV pilus assembly protein ComGB Machinery gene
  QOR61_RS01135 comGC/cglC 196308..196637 (+) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  QOR61_RS01140 comYD 196612..197025 (+) 414 WP_000244259.1 competence type IV pilus minor pilin ComGD Machinery gene
  QOR61_RS01145 comGE 196997..197296 (+) 300 WP_001872488.1 competence type IV pilus minor pilin ComGE -
  QOR61_RS01150 comGF 197250..197711 (+) 462 WP_001874060.1 competence type IV pilus minor pilin ComGF -
  QOR61_RS01155 comGG 197689..198060 (+) 372 WP_000601101.1 competence type IV pilus minor pilin ComGG -
  QOR61_RS01160 comYH 198175..199149 (+) 975 WP_001008569.1 class I SAM-dependent methyltransferase Machinery gene
  QOR61_RS01165 - 199181..200374 (+) 1194 WP_000047534.1 acetate kinase -
  QOR61_RS01170 - 200502..200694 (+) 193 Protein_177 helix-turn-helix transcriptional regulator -
  QOR61_RS01175 - 200673..200939 (+) 267 Protein_178 hypothetical protein -

Sequence

Protein


Download         Length: 109 a.a.        Molecular weight: 12129.27 Da        Isoelectric Point: 10.0311

>NTDB_id=1159295 QOR61_RS01135 WP_000793380.1 196308..196637(+) (comGC/cglC) [Streptococcus agalactiae isolate MRI Z2-299]
MKNLLLKCKDKKVKAFTLLEMLVVLIIISVLLLLFVPNLSKQKESVTRTGNAAVVKVVESQAELFELQETGRKASLSTLK
SGGYITEKQEKAYLDYYKDSSNGSQKISS

Nucleotide


Download         Length: 330 bp        

>NTDB_id=1159295 QOR61_RS01135 WP_000793380.1 196308..196637(+) (comGC/cglC) [Streptococcus agalactiae isolate MRI Z2-299]
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAAATGTTAGTTGTTTTGATCAT
TATTTCGGTCTTGTTGTTATTGTTTGTACCCAATTTATCAAAACAAAAGGAAAGTGTCACAAGAACTGGAAATGCCGCTG
TTGTCAAGGTTGTAGAAAGTCAAGCCGAACTTTTTGAACTGCAAGAAACAGGTAGAAAAGCTAGTTTATCCACTCTAAAA
TCTGGAGGATATATTACTGAAAAGCAAGAAAAAGCCTATTTAGATTATTATAAAGACAGTTCCAATGGTTCTCAGAAAAT
TTCAAGTTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1EKJ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

60.55

100

0.606
  comGC/cglC Streptococcus mitis SK321

59.633

100

0.596
  comYC Streptococcus gordonii str. Challis substr. CH1

61.165

94.495

0.578
  comGC/cglC Streptococcus pneumoniae TIGR4

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae R6

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae Rx1

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae D39

57.798

100

0.578
  comYC Streptococcus mutans UA159

55.238

96.33

0.532
  comYC Streptococcus mutans UA140

55.238

96.33

0.532
  comGC Lactococcus lactis subsp. cremoris KW2

63.043

84.404

0.532
  comYC Streptococcus suis isolate S10

65.854

75.229

0.495

Multiple sequence alignment