Detailed information NTG1159148

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: QOR58_RS05525
• Genome accession: NZ_OX460941
• Coordinates: 1050609..1051451 (-)
• Length: 280 a.a.
• NCBI ID: WP_001015250.1
• Uniprot ID: X5JZS7
• Organism: Streptococcus agalactiae isolate MRI Z2-304
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1045609..1056451

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QOR58_RS05515	-	1047557..1048258 (-)	702	WP_000120350.1	ABC transporter ATP-binding protein	-
QOR58_RS05520	topA	1048394..1050514 (-)	2121	WP_283571588.1	type I DNA topoisomerase	-
QOR58_RS05525	dprA	1050609..1051451 (-)	843	WP_001015250.1	DNA-processing protein DprA	Machinery gene
QOR58_RS05530	-	1051590..1052618 (-)	1029	WP_000162771.1	siderophore ABC transporter substrate-binding protein	-
QOR58_RS05535	-	1052680..1053441 (-)	762	WP_000614759.1	ATP-binding cassette domain-containing protein	-
QOR58_RS05540	-	1053438..1054412 (-)	975	WP_000588579.1	iron chelate uptake ABC transporter family permease subunit	-
QOR58_RS05545	ceuB	1054409..1055371 (-)	963	WP_000735590.1	iron chelate uptake ABC transporter family permease subunit	Machinery gene
QOR58_RS05550	-	1055611..1056159 (-)	549	WP_000136503.1	sugar O-acetyltransferase	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31271.32 Da
• Isoelectric Point: 9.3800

>NTDB_id=1159148 QOR58_RS05525 WP_001015250.1 1050609..1051451(-) (dprA) [Streptococcus agalactiae isolate MRI Z2-304]
MNHFELFKLKKAGLTNLNINNIINYLKKNSLTSLSVRNMAVVSKCKNPTFFIENYKQLDLKKLRQEFKKFPVLSILDSNY
PLELKEIYNPPVLLFYQGNIELLSKPKLAVVGARQASQIGCQSVKKIIKETNNQFVIVSGLARGIDTAAHVSALKNGGSS
IAVIGSGLDVYYPTENKKLQEYMSYNHLVLSEYFTGEQPLKFHFPERNRIIAGLCQGIVVAEAKMRSGSLITCERALEEG
REVFAIPGNIIDGKSDGCHHLIQEGAKCIISGKDILSEYQ

Nucleotide

• Length: 843 bp

>NTDB_id=1159148 QOR58_RS05525 WP_001015250.1 1050609..1051451(-) (dprA) [Streptococcus agalactiae isolate MRI Z2-304]
ATGAATCATTTTGAACTATTTAAGCTTAAAAAAGCTGGACTAACAAATCTTAATATCAACAATATTATCAACTACCTTAA
AAAGAATAGTTTAACTTCTCTATCTGTTCGCAATATGGCCGTAGTGTCAAAATGTAAAAACCCTACTTTCTTTATAGAAA
ATTATAAACAGCTAGACCTTAAAAAACTTCGACAAGAATTCAAAAAATTTCCAGTTCTATCGATTTTGGATTCTAACTAT
CCTTTAGAGTTAAAAGAAATATATAATCCACCAGTTCTACTTTTTTATCAGGGTAATATTGAACTTCTATCTAAACCTAA
ATTAGCTGTAGTGGGAGCAAGACAGGCATCTCAGATAGGTTGTCAGTCTGTTAAAAAGATTATCAAGGAGACTAACAATC
AATTTGTTATCGTAAGTGGTTTAGCGCGTGGCATTGATACAGCAGCACATGTTAGTGCTTTAAAAAATGGCGGCAGTAGT
ATAGCTGTTATCGGGAGTGGTTTAGATGTTTATTATCCAACGGAGAATAAGAAACTTCAAGAATATATGTCATATAATCA
TCTCGTATTATCAGAATATTTTACCGGAGAACAACCCTTGAAATTTCATTTCCCCGAACGTAACCGTATTATTGCAGGGC
TGTGTCAAGGTATTGTGGTTGCCGAAGCTAAGATGAGATCTGGAAGTTTAATTACCTGTGAAAGAGCATTAGAAGAGGGA
CGAGAAGTTTTTGCCATTCCCGGAAATATTATCGATGGCAAATCAGATGGATGCCACCATCTTATCCAAGAAGGAGCTAA
ATGCATTATTTCAGGAAAAGATATCCTTTCTGAATATCAGTAG

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (69-270)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-63)

3D structure

• AlphaFold DB: X5JZS7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	70.251	99.643	0.7
dprA/cilB/dalA	Streptococcus mitis SK321	62.5	100	0.625
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae D39	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae R6	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	61.786	100	0.618
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	61.429	100	0.614
dprA	Lactococcus lactis subsp. cremoris KW2	61.29	99.643	0.611
dprA	Latilactobacillus sakei subsp. sakei 23K	42.231	89.643	0.379
dprA	Haemophilus influenzae Rd KW20	37.132	97.143	0.361