Detailed information
Bioinformatically predicted
Overview
| Name | comYA | Type | Machinery gene |
| Locus tag | QOR56_RS01155 | Genome accession | NZ_OX460906 |
| Coordinates | 198430..199401 (+) | Length | 323 a.a. |
| NCBI ID | WP_000250798.1 | Uniprot ID | - |
| Organism | Streptococcus agalactiae isolate MRI Z2-265 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 196824..256248 | 198430..199401 | within | 0 |
| IS/Tn | 196924..198384 | 198430..199401 | flank | 46 |
Gene organization within MGE regions
Location: 196824..256248
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QOR56_RS01150 | - | 196924..198384 (+) | 1461 | WP_000468685.1 | IS1182-like element IS1563 family transposase | - |
| QOR56_RS01155 | comYA | 198430..199401 (+) | 972 | WP_000250798.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| QOR56_RS01160 | comYB | 199295..200338 (+) | 1044 | WP_223297804.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| QOR56_RS01165 | comGF | 200335..200790 (+) | 456 | WP_000793378.1 | competence type IV pilus minor pilin ComGF | - |
| QOR56_RS01170 | comGG | 200768..201139 (+) | 372 | WP_000601101.1 | competence type IV pilus minor pilin ComGG | - |
| QOR56_RS01175 | comYH | 201254..202228 (+) | 975 | WP_001008569.1 | class I SAM-dependent methyltransferase | Machinery gene |
| QOR56_RS01180 | - | 202260..203453 (+) | 1194 | WP_000047534.1 | acetate kinase | - |
| QOR56_RS01185 | - | 203581..203773 (+) | 193 | Protein_180 | helix-turn-helix transcriptional regulator | - |
| QOR56_RS01190 | - | 203752..204018 (+) | 267 | Protein_181 | hypothetical protein | - |
| QOR56_RS01195 | - | 204114..205289 (+) | 1176 | WP_000191687.1 | IS256-like element ISSag11 family transposase | - |
| QOR56_RS01200 | - | 205407..206072 (+) | 666 | WP_000008108.1 | type II CAAX endopeptidase family protein | - |
| QOR56_RS01205 | - | 206050..207540 (-) | 1491 | WP_283572044.1 | IS1182-like element IS1563 family transposase | - |
| QOR56_RS01210 | proC | 207656..208426 (-) | 771 | WP_001872483.1 | pyrroline-5-carboxylate reductase | - |
| QOR56_RS01215 | pepA | 208496..209563 (-) | 1068 | WP_001281321.1 | glutamyl aminopeptidase | - |
| QOR56_RS01220 | - | 209743..209982 (-) | 240 | WP_000660180.1 | hypothetical protein | - |
| QOR56_RS01225 | - | 210143..210427 (+) | 285 | WP_000791272.1 | DUF4651 domain-containing protein | - |
| QOR56_RS01230 | - | 210424..210747 (+) | 324 | WP_000602783.1 | thioredoxin family protein | - |
| QOR56_RS01235 | ytpR | 210780..211406 (+) | 627 | WP_000578331.1 | YtpR family tRNA-binding protein | - |
| QOR56_RS01240 | - | 211466..212176 (-) | 711 | WP_283572045.1 | class I SAM-dependent methyltransferase | - |
| QOR56_RS01245 | ssbA | 212257..212652 (+) | 396 | WP_000282449.1 | single-stranded DNA-binding protein | Machinery gene |
| QOR56_RS01250 | - | 212776..213420 (+) | 645 | WP_000416617.1 | HAD family hydrolase | - |
| QOR56_RS01255 | - | 213447..215192 (+) | 1746 | WP_000930335.1 | LytS/YhcK type 5TM receptor domain-containing protein | - |
| QOR56_RS01260 | - | 215173..215913 (+) | 741 | WP_000697628.1 | LytTR family transcriptional regulator DNA-binding domain-containing protein | - |
| QOR56_RS01265 | - | 216083..216538 (+) | 456 | WP_000683316.1 | CidA/LrgA family protein | - |
| QOR56_RS01270 | lrgB | 216540..217268 (+) | 729 | WP_000421730.1 | antiholin-like protein LrgB | - |
| QOR56_RS01275 | - | 217510..219138 (+) | 1629 | WP_000170504.1 | ABC transporter substrate-binding protein | - |
| QOR56_RS01280 | - | 219251..220228 (+) | 978 | WP_000680646.1 | ABC transporter permease | - |
| QOR56_RS01285 | - | 220225..221046 (+) | 822 | WP_000603398.1 | ABC transporter permease | - |
| QOR56_RS01290 | - | 221058..221861 (+) | 804 | WP_000140987.1 | ABC transporter ATP-binding protein | - |
| QOR56_RS01295 | - | 221845..222471 (+) | 627 | WP_000171302.1 | ABC transporter ATP-binding protein | - |
| QOR56_RS01300 | treP | 222754..224784 (+) | 2031 | WP_000434614.1 | PTS system trehalose-specific EIIBC component | - |
| QOR56_RS01305 | treC | 225005..226630 (+) | 1626 | WP_000151020.1 | alpha,alpha-phosphotrehalase | - |
| QOR56_RS01310 | - | 226650..227594 (-) | 945 | WP_000222594.1 | IS30 family transposase | - |
| QOR56_RS01315 | - | 227897..229933 (+) | 2037 | WP_000228179.1 | BglG family transcription antiterminator | - |
| QOR56_RS01320 | - | 229936..230220 (+) | 285 | WP_000944235.1 | PTS sugar transporter subunit IIB | - |
| QOR56_RS01325 | - | 230233..231588 (+) | 1356 | WP_000677352.1 | PTS ascorbate transporter subunit IIC | - |
| QOR56_RS01330 | - | 231591..232448 (+) | 858 | WP_016502451.1 | transketolase | - |
| QOR56_RS01335 | - | 232445..233374 (+) | 930 | WP_283572048.1 | transketolase C-terminal domain-containing protein | - |
| QOR56_RS01340 | - | 233483..234742 (+) | 1260 | WP_001203064.1 | ferric reductase-like transmembrane domain-containing protein | - |
| QOR56_RS01345 | rpsO | 234830..235099 (+) | 270 | WP_001018249.1 | 30S ribosomal protein S15 | - |
| QOR56_RS01350 | pnp | 235480..237609 (+) | 2130 | WP_283573716.1 | polyribonucleotide nucleotidyltransferase | - |
| QOR56_RS01355 | - | 237611..238363 (+) | 753 | WP_000204782.1 | SseB family protein | - |
| QOR56_RS01360 | cysE | 238372..238956 (+) | 585 | WP_000539954.1 | serine O-acetyltransferase | - |
| QOR56_RS01365 | - | 238966..239148 (+) | 183 | WP_000656476.1 | lipoprotein | - |
| QOR56_RS01370 | cysS | 239145..240488 (+) | 1344 | WP_000591129.1 | cysteine--tRNA ligase | - |
| QOR56_RS01375 | - | 240481..240867 (+) | 387 | WP_000568031.1 | Mini-ribonuclease 3 | - |
| QOR56_RS01380 | rlmB | 240970..241725 (+) | 756 | WP_000178025.1 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB | - |
| QOR56_RS01385 | - | 241722..242240 (+) | 519 | WP_000716639.1 | NYN domain-containing protein | - |
| QOR56_RS01390 | - | 242333..243193 (+) | 861 | WP_000143139.1 | DegV family protein | - |
| QOR56_RS01395 | - | 243731..243850 (+) | 120 | Protein_222 | helix-turn-helix domain-containing protein | - |
| QOR56_RS01400 | rplM | 244075..244521 (+) | 447 | WP_001867156.1 | 50S ribosomal protein L13 | - |
| QOR56_RS01405 | rpsI | 244542..244934 (+) | 393 | WP_000035940.1 | 30S ribosomal protein S9 | - |
| QOR56_RS01410 | - | 245044..246261 (-) | 1218 | WP_283572049.1 | tyrosine-type recombinase/integrase | - |
| QOR56_RS01415 | - | 246333..246593 (-) | 261 | WP_001196071.1 | helix-turn-helix domain-containing protein | - |
| QOR56_RS01420 | - | 246652..247680 (-) | 1029 | WP_283572050.1 | replication initiation factor domain-containing protein | - |
| QOR56_RS01425 | - | 247683..248105 (-) | 423 | WP_000067972.1 | hypothetical protein | - |
| QOR56_RS01430 | - | 248282..248971 (+) | 690 | WP_283573717.1 | ATP-binding cassette domain-containing protein | - |
| QOR56_RS01435 | - | 248968..249705 (+) | 738 | WP_000812013.1 | ABC transporter ATP-binding protein | - |
| QOR56_RS01440 | - | 249707..251614 (+) | 1908 | WP_000638297.1 | FtsX-like permease family protein | - |
| QOR56_RS01445 | - | 251654..253216 (+) | 1563 | WP_283572053.1 | hypothetical protein | - |
| QOR56_RS01450 | - | 253197..253802 (+) | 606 | WP_002982799.1 | response regulator transcription factor | - |
| QOR56_RS01455 | - | 254014..254289 (-) | 276 | WP_000207531.1 | helix-turn-helix transcriptional regulator | - |
| QOR56_RS01460 | - | 254276..254641 (-) | 366 | WP_000876944.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| QOR56_RS01465 | - | 255353..256213 (+) | 861 | WP_000471418.1 | Rgg/GadR/MutR family transcriptional regulator | - |
Sequence
Protein
Download Length: 323 a.a. Molecular weight: 36768.25 Da Isoelectric Point: 6.9167
>NTDB_id=1158720 QOR56_RS01155 WP_000250798.1 198430..199401(+) (comYA) [Streptococcus agalactiae isolate MRI Z2-265]
MVQSLAKHVIHQAVEVNAQDIYIIPKGDCYELYMRIDDERRFIDVFEFNRMASLISHFKFVAGMNVGEKRRSQLGSCDYE
LSEGRLVSLRLSSVGDYRGQESLVIRILYSGHQDLKYWFDNIKQMKEVLGARGLYLFSGPVGSGKTTLMYQLASEVFKNK
QIITIEDPVEIKNDKMLQLQLNEDIGMTYDALIKLSLRHRPDILIIGEIRDQATARAVIRASLTGVMVFSTIHAKSIPGV
YDRLIELGVNYQELENSLKLIAYQRLIGGGSLIDFETGNFKKHSSDKWNRQVDILAEEGHISKKQAQVEKIIPQETTESS
PTF
MVQSLAKHVIHQAVEVNAQDIYIIPKGDCYELYMRIDDERRFIDVFEFNRMASLISHFKFVAGMNVGEKRRSQLGSCDYE
LSEGRLVSLRLSSVGDYRGQESLVIRILYSGHQDLKYWFDNIKQMKEVLGARGLYLFSGPVGSGKTTLMYQLASEVFKNK
QIITIEDPVEIKNDKMLQLQLNEDIGMTYDALIKLSLRHRPDILIIGEIRDQATARAVIRASLTGVMVFSTIHAKSIPGV
YDRLIELGVNYQELENSLKLIAYQRLIGGGSLIDFETGNFKKHSSDKWNRQVDILAEEGHISKKQAQVEKIIPQETTESS
PTF
Nucleotide
Download Length: 972 bp
>NTDB_id=1158720 QOR56_RS01155 WP_000250798.1 198430..199401(+) (comYA) [Streptococcus agalactiae isolate MRI Z2-265]
ATGGTTCAATCATTAGCAAAGCACGTCATCCATCAGGCAGTAGAAGTAAATGCTCAAGATATTTATATTATTCCCAAAGG
TGATTGTTATGAACTCTATATGCGTATTGATGATGAAAGGCGGTTTATTGATGTTTTTGAGTTTAATAGGATGGCTAGTC
TTATTAGTCACTTTAAATTTGTGGCAGGCATGAACGTTGGAGAAAAAAGACGAAGTCAATTAGGTTCTTGTGACTATGAA
CTGTCAGAGGGAAGACTGGTTTCATTACGACTATCAAGTGTGGGAGATTATCGTGGTCAAGAATCTTTAGTTATTCGTAT
TTTGTATTCAGGTCATCAGGACTTAAAATATTGGTTTGATAATATAAAGCAAATGAAGGAAGTACTGGGTGCAAGAGGGC
TATATCTTTTTTCCGGCCCTGTGGGGAGTGGTAAAACAACTCTCATGTATCAATTAGCTTCAGAAGTATTTAAAAATAAG
CAAATTATCACGATTGAAGATCCGGTAGAAATCAAGAATGACAAGATGTTACAACTCCAATTGAATGAGGATATTGGAAT
GACTTATGATGCTTTAATCAAACTGTCTTTACGGCATCGTCCAGATATTTTAATTATCGGAGAGATTAGAGATCAAGCGA
CGGCCCGTGCTGTTATTCGTGCAAGTTTAACGGGAGTGATGGTTTTTTCTACTATTCATGCTAAAAGTATTCCCGGAGTC
TATGATAGGCTTATAGAATTAGGGGTTAACTATCAAGAGTTAGAAAATAGTCTAAAATTAATAGCATATCAACGTTTAAT
TGGAGGAGGAAGCCTAATTGACTTTGAGACAGGTAATTTTAAAAAACACTCATCAGACAAGTGGAATAGACAAGTGGATA
TCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAAACAACGGAAAGTAGT
CCAACTTTTTAA
ATGGTTCAATCATTAGCAAAGCACGTCATCCATCAGGCAGTAGAAGTAAATGCTCAAGATATTTATATTATTCCCAAAGG
TGATTGTTATGAACTCTATATGCGTATTGATGATGAAAGGCGGTTTATTGATGTTTTTGAGTTTAATAGGATGGCTAGTC
TTATTAGTCACTTTAAATTTGTGGCAGGCATGAACGTTGGAGAAAAAAGACGAAGTCAATTAGGTTCTTGTGACTATGAA
CTGTCAGAGGGAAGACTGGTTTCATTACGACTATCAAGTGTGGGAGATTATCGTGGTCAAGAATCTTTAGTTATTCGTAT
TTTGTATTCAGGTCATCAGGACTTAAAATATTGGTTTGATAATATAAAGCAAATGAAGGAAGTACTGGGTGCAAGAGGGC
TATATCTTTTTTCCGGCCCTGTGGGGAGTGGTAAAACAACTCTCATGTATCAATTAGCTTCAGAAGTATTTAAAAATAAG
CAAATTATCACGATTGAAGATCCGGTAGAAATCAAGAATGACAAGATGTTACAACTCCAATTGAATGAGGATATTGGAAT
GACTTATGATGCTTTAATCAAACTGTCTTTACGGCATCGTCCAGATATTTTAATTATCGGAGAGATTAGAGATCAAGCGA
CGGCCCGTGCTGTTATTCGTGCAAGTTTAACGGGAGTGATGGTTTTTTCTACTATTCATGCTAAAAGTATTCCCGGAGTC
TATGATAGGCTTATAGAATTAGGGGTTAACTATCAAGAGTTAGAAAATAGTCTAAAATTAATAGCATATCAACGTTTAAT
TGGAGGAGGAAGCCTAATTGACTTTGAGACAGGTAATTTTAAAAAACACTCATCAGACAAGTGGAATAGACAAGTGGATA
TCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAAACAACGGAAAGTAGT
CCAACTTTTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYA | Streptococcus mutans UA159 |
68.81 |
96.285 |
0.663 |
| comYA | Streptococcus mutans UA140 |
68.81 |
96.285 |
0.663 |
| comYA | Streptococcus gordonii str. Challis substr. CH1 |
63.636 |
98.762 |
0.628 |
| comGA/cglA/cilD | Streptococcus mitis NCTC 12261 |
62.701 |
96.285 |
0.604 |
| comGA/cglA/cilD | Streptococcus pneumoniae Rx1 |
61.736 |
96.285 |
0.594 |
| comGA/cglA/cilD | Streptococcus pneumoniae D39 |
61.736 |
96.285 |
0.594 |
| comGA/cglA/cilD | Streptococcus pneumoniae R6 |
61.736 |
96.285 |
0.594 |
| comGA/cglA/cilD | Streptococcus pneumoniae TIGR4 |
61.736 |
96.285 |
0.594 |
| comGA/cglA | Streptococcus sobrinus strain NIDR 6715-7 |
61.935 |
95.975 |
0.594 |
| comGA | Lactococcus lactis subsp. cremoris KW2 |
50.621 |
99.69 |
0.505 |