Detailed information NTG1155146

Bioinformatically predicted

Overview

• Name: cinA
• Type: Machinery gene
• Locus tag: QML77_RS00465
• Genome accession: NZ_OX346407
• Coordinates: 92027..93280 (+)
• Length: 417 a.a.
• NCBI ID: WP_281956923.1
• Uniprot ID: -
• Organism: Enterococcus cecorum isolate CIRMBP-1274
• Function: require for competence (predicted from homology) Unclear

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	91101..91919	92027..93280	flank	108

Gene organization within MGE regions

Location: 91101..93280

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QML77_RS00465 (CIRMBP1274_00091)	cinA	92027..93280 (+)	1254	WP_281956923.1	competence/damage-inducible protein A	Machinery gene

Sequence

Protein

• Length: 417 a.a.
• Molecular weight: 45830.21 Da
• Isoelectric Point: 4.9400

>NTDB_id=1155146 QML77_RS00465 WP_281956923.1 92027..93280(+) (cinA) [Enterococcus cecorum isolate CIRMBP-1274]
MNAEIIAVGTEILMGQIVNSNAAYLSEQLANLGINVYYHVAVGDNEKRLTACLERAKSRSDLIVLCGGLGPTQDDLTKQT
VAKFVNQELVYDPAGHARLMDYFAKTKREMTENNLLQALTFKDGRGIANPNGLAVGIYYEDSDHTHYLLLPGPPRELKAM
FRQNVVPLLREINPQDTKLYSRVLRFYGIGESQLVTLLADFIDHQTNPTIAPYAKTNEVTLRLTANTSTQDQADRLLDEL
EEKIQALAGAYFYGYGDDFSLAEAMIAQLKEKKRTISVAESLTAGLFASTLGQYPGVSQVFKGGVVTYSLEMKAALLDID
ADYLREVGTVSEACVTLMAKNMQQKAQTDYAIAFSGVAGPDQLEGQAVGTVWMALATPNGVQTYCKQFPHGRNEIRQAAV
MFGLNLVYRALLAEEQA

Nucleotide

• Length: 1254 bp

>NTDB_id=1155146 QML77_RS00465 WP_281956923.1 92027..93280(+) (cinA) [Enterococcus cecorum isolate CIRMBP-1274]
ATGAATGCAGAAATCATTGCAGTCGGAACAGAGATTTTGATGGGGCAAATCGTTAATTCTAATGCGGCCTATCTTTCAGA
GCAATTAGCCAATTTGGGTATTAATGTTTATTATCATGTCGCAGTCGGAGATAATGAAAAGCGATTGACGGCCTGTCTTG
AACGTGCCAAAAGTCGGAGTGATTTAATCGTGCTTTGTGGTGGTTTGGGGCCTACACAAGATGATTTAACCAAGCAAACT
GTAGCCAAATTTGTCAATCAAGAGTTAGTCTATGATCCAGCAGGGCATGCACGTTTGATGGATTATTTTGCCAAGACCAA
GCGAGAAATGACCGAAAATAATTTATTACAAGCCCTCACTTTTAAGGATGGTCGTGGTATTGCCAATCCAAATGGTCTAG
CGGTCGGTATTTATTATGAAGATAGCGATCATACTCACTATTTATTATTGCCTGGGCCACCGCGCGAGTTAAAGGCGATG
TTTCGTCAAAATGTTGTGCCACTTTTGCGTGAAATCAATCCGCAAGATACGAAGCTCTATTCTCGGGTGTTGCGTTTTTA
TGGGATTGGCGAATCGCAGTTAGTCACGCTTTTAGCGGATTTCATTGACCATCAGACTAACCCAACGATCGCGCCTTATG
CCAAAACCAATGAAGTGACGTTGCGCTTGACAGCCAATACATCTACCCAAGATCAAGCGGATAGGTTGCTTGATGAATTA
GAGGAGAAAATTCAAGCTTTGGCCGGTGCTTACTTTTATGGTTATGGGGATGATTTTTCTTTAGCGGAGGCGATGATTGC
CCAATTAAAAGAGAAAAAACGGACAATCAGCGTGGCTGAGAGTTTGACAGCCGGCCTTTTTGCTTCTACCTTGGGACAAT
ATCCGGGGGTGTCACAGGTCTTTAAAGGTGGTGTGGTCACTTATTCGCTTGAGATGAAGGCGGCTTTATTAGATATTGAT
GCCGATTATTTACGAGAAGTCGGGACGGTGAGTGAAGCTTGTGTCACCTTAATGGCTAAAAATATGCAGCAAAAAGCGCA
AACGGATTATGCCATTGCTTTTAGTGGCGTGGCAGGACCGGATCAATTAGAAGGCCAAGCAGTCGGAACTGTCTGGATGG
CTTTGGCGACTCCAAATGGGGTACAGACTTATTGCAAACAGTTCCCCCATGGCCGCAATGAAATCCGCCAAGCCGCTGTG
ATGTTTGGGTTAAATCTCGTTTATCGCGCGCTTTTAGCTGAAGAACAAGCCTAA

Domains

Predicted by InterproScan.

• Damage-inducible protein CinA KH domain (CinA_KH) (181-254)

• Competence-damaged protein (CinA) (260-410)

• Probable molybdopterin binding domain (MoCF_biosynth) (5-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cinA	Streptococcus mutans UA159	51.069	100	0.516
cinA	Streptococcus pneumoniae TIGR4	50.827	100	0.516
cinA	Streptococcus pneumoniae R6	50.591	100	0.513
cinA	Streptococcus mitis SK321	50.591	100	0.513
cinA	Streptococcus pneumoniae Rx1	50.591	100	0.513
cinA	Streptococcus pneumoniae D39	50.355	100	0.511
cinA	Streptococcus mitis NCTC 12261	49.882	100	0.506
cinA	Bacillus subtilis subsp. subtilis str. 168	44.878	98.321	0.441
cinA	Streptococcus suis isolate S10	47.273	92.326	0.436