Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   QML77_RS00465 Genome accession   NZ_OX346407
Coordinates   92027..93280 (+) Length   417 a.a.
NCBI ID   WP_281956923.1    Uniprot ID   -
Organism   Enterococcus cecorum isolate CIRMBP-1274     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 87027..98280
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QML77_RS00445 (CIRMBP1274_00086) - 87318..88607 (+) 1290 WP_281956920.1 pitrilysin family protein -
  QML77_RS00450 (CIRMBP1274_00087) - 88795..89733 (+) 939 WP_281956921.1 helix-turn-helix domain-containing protein -
  QML77_RS00455 (CIRMBP1274_00088) pgsA 89844..90422 (+) 579 WP_026209940.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QML77_RS00460 - 90499..91919 (+) 1421 WP_281956922.1 IS3 family transposase -
  QML77_RS00465 (CIRMBP1274_00091) cinA 92027..93280 (+) 1254 WP_281956923.1 competence/damage-inducible protein A Machinery gene
  QML77_RS00470 (CIRMBP1274_00092) recA 93398..94444 (+) 1047 WP_281956924.1 recombinase RecA Machinery gene
  QML77_RS00475 (CIRMBP1274_00093) rny 94663..96222 (+) 1560 WP_281956925.1 ribonuclease Y -
  QML77_RS00480 (CIRMBP1274_00094) - 96438..96659 (+) 222 WP_047241714.1 helix-turn-helix transcriptional regulator -
  QML77_RS00485 (CIRMBP1274_00095) - 96646..97407 (+) 762 WP_047241713.1 DUF3169 family protein -

Sequence

Protein


Download         Length: 417 a.a.        Molecular weight: 45830.21 Da        Isoelectric Point: 4.9400

>NTDB_id=1155146 QML77_RS00465 WP_281956923.1 92027..93280(+) (cinA) [Enterococcus cecorum isolate CIRMBP-1274]
MNAEIIAVGTEILMGQIVNSNAAYLSEQLANLGINVYYHVAVGDNEKRLTACLERAKSRSDLIVLCGGLGPTQDDLTKQT
VAKFVNQELVYDPAGHARLMDYFAKTKREMTENNLLQALTFKDGRGIANPNGLAVGIYYEDSDHTHYLLLPGPPRELKAM
FRQNVVPLLREINPQDTKLYSRVLRFYGIGESQLVTLLADFIDHQTNPTIAPYAKTNEVTLRLTANTSTQDQADRLLDEL
EEKIQALAGAYFYGYGDDFSLAEAMIAQLKEKKRTISVAESLTAGLFASTLGQYPGVSQVFKGGVVTYSLEMKAALLDID
ADYLREVGTVSEACVTLMAKNMQQKAQTDYAIAFSGVAGPDQLEGQAVGTVWMALATPNGVQTYCKQFPHGRNEIRQAAV
MFGLNLVYRALLAEEQA

Nucleotide


Download         Length: 1254 bp        

>NTDB_id=1155146 QML77_RS00465 WP_281956923.1 92027..93280(+) (cinA) [Enterococcus cecorum isolate CIRMBP-1274]
ATGAATGCAGAAATCATTGCAGTCGGAACAGAGATTTTGATGGGGCAAATCGTTAATTCTAATGCGGCCTATCTTTCAGA
GCAATTAGCCAATTTGGGTATTAATGTTTATTATCATGTCGCAGTCGGAGATAATGAAAAGCGATTGACGGCCTGTCTTG
AACGTGCCAAAAGTCGGAGTGATTTAATCGTGCTTTGTGGTGGTTTGGGGCCTACACAAGATGATTTAACCAAGCAAACT
GTAGCCAAATTTGTCAATCAAGAGTTAGTCTATGATCCAGCAGGGCATGCACGTTTGATGGATTATTTTGCCAAGACCAA
GCGAGAAATGACCGAAAATAATTTATTACAAGCCCTCACTTTTAAGGATGGTCGTGGTATTGCCAATCCAAATGGTCTAG
CGGTCGGTATTTATTATGAAGATAGCGATCATACTCACTATTTATTATTGCCTGGGCCACCGCGCGAGTTAAAGGCGATG
TTTCGTCAAAATGTTGTGCCACTTTTGCGTGAAATCAATCCGCAAGATACGAAGCTCTATTCTCGGGTGTTGCGTTTTTA
TGGGATTGGCGAATCGCAGTTAGTCACGCTTTTAGCGGATTTCATTGACCATCAGACTAACCCAACGATCGCGCCTTATG
CCAAAACCAATGAAGTGACGTTGCGCTTGACAGCCAATACATCTACCCAAGATCAAGCGGATAGGTTGCTTGATGAATTA
GAGGAGAAAATTCAAGCTTTGGCCGGTGCTTACTTTTATGGTTATGGGGATGATTTTTCTTTAGCGGAGGCGATGATTGC
CCAATTAAAAGAGAAAAAACGGACAATCAGCGTGGCTGAGAGTTTGACAGCCGGCCTTTTTGCTTCTACCTTGGGACAAT
ATCCGGGGGTGTCACAGGTCTTTAAAGGTGGTGTGGTCACTTATTCGCTTGAGATGAAGGCGGCTTTATTAGATATTGAT
GCCGATTATTTACGAGAAGTCGGGACGGTGAGTGAAGCTTGTGTCACCTTAATGGCTAAAAATATGCAGCAAAAAGCGCA
AACGGATTATGCCATTGCTTTTAGTGGCGTGGCAGGACCGGATCAATTAGAAGGCCAAGCAGTCGGAACTGTCTGGATGG
CTTTGGCGACTCCAAATGGGGTACAGACTTATTGCAAACAGTTCCCCCATGGCCGCAATGAAATCCGCCAAGCCGCTGTG
ATGTTTGGGTTAAATCTCGTTTATCGCGCGCTTTTAGCTGAAGAACAAGCCTAA

Domains

Predicted by InterProScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(181-254)

Competence-damaged protein (CinA)

(260-410)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

51.069

100

0.516
  cinA Streptococcus pneumoniae TIGR4

50.827

100

0.516
  cinA Streptococcus pneumoniae R6

50.591

100

0.513
  cinA Streptococcus mitis SK321

50.591

100

0.513
  cinA Streptococcus pneumoniae Rx1

50.591

100

0.513
  cinA Streptococcus pneumoniae D39

50.355

100

0.511
  cinA Streptococcus mitis NCTC 12261

49.882

100

0.506
  cinA Bacillus subtilis subsp. subtilis str. 168

44.878

98.321

0.441
  cinA Streptococcus suis isolate S10

47.273

92.326

0.436

Multiple sequence alignment