Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   KJA93_RS12510 Genome accession   NZ_OD940431
Coordinates   2618845..2620089 (-) Length   414 a.a.
NCBI ID   WP_126254808.1    Uniprot ID   -
Organism   Enterococcus faecalis isolate TM6294     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2613845..2625089
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KJA93_RS12485 (TM6294_02552) - 2614157..2615620 (-) 1464 WP_002383207.1 glycoside hydrolase family 1 protein -
  KJA93_RS12490 (TM6294_02553) - 2615602..2615943 (-) 342 WP_002359005.1 PTS lactose/cellobiose transporter subunit IIA -
  KJA93_RS12495 (TM6294_02554) - 2615963..2617213 (-) 1251 WP_126254807.1 PTS transporter subunit EIIC -
  KJA93_RS12500 (TM6294_02555) - 2617218..2617523 (-) 306 WP_010821936.1 hypothetical protein -
  KJA93_RS12505 (TM6294_02556) recA 2617685..2618731 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  KJA93_RS12510 (TM6294_02557) cinA 2618845..2620089 (-) 1245 WP_126254808.1 competence/damage-inducible protein A Machinery gene
  KJA93_RS12515 (TM6294_02558) - 2620281..2621486 (+) 1206 WP_002359001.1 hypothetical protein -
  KJA93_RS12520 (TM6294_02559) - 2621562..2622191 (-) 630 WP_002354854.1 NAD(P)-dependent oxidoreductase -
  KJA93_RS12525 (TM6294_02560) - 2622250..2622675 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  KJA93_RS12530 (TM6294_02561) - 2622764..2623147 (-) 384 WP_002358999.1 YccF domain-containing protein -
  KJA93_RS12535 (TM6294_02562) - 2623311..2624102 (+) 792 WP_002354848.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45194.27 Da        Isoelectric Point: 4.6302

>NTDB_id=1150666 KJA93_RS12510 WP_126254808.1 2618845..2620089(-) (cinA) [Enterococcus faecalis isolate TM6294]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEKRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINEK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=1150666 KJA93_RS12510 WP_126254808.1 2618845..2620089(-) (cinA) [Enterococcus faecalis isolate TM6294]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAAAAAAGAAGTGATTTAATTGTCCTGTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTTGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATTTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAGTTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAGCATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATGAAAAATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-409)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.392

100

0.529
  cinA Streptococcus mitis SK321

51.179

100

0.524
  cinA Streptococcus mitis NCTC 12261

50.943

100

0.522
  cinA Streptococcus pneumoniae TIGR4

50.236

100

0.514
  cinA Streptococcus pneumoniae D39

50

100

0.512
  cinA Streptococcus pneumoniae R6

49.764

100

0.51
  cinA Streptococcus pneumoniae Rx1

49.764

100

0.51
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.282

99.275

0.44

Multiple sequence alignment