Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   CKV85_RS10960 Genome accession   NZ_LT906454
Coordinates   2204542..2205798 (-) Length   418 a.a.
NCBI ID   WP_095123610.1    Uniprot ID   -
Organism   Streptococcus acidominimus strain NCTC11291     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2199542..2210798
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV85_RS10935 (SAMEA4504048_02335) - 2200068..2200616 (+) 549 WP_095123608.1 DUF4352 domain-containing protein -
  CKV85_RS10940 (SAMEA4504048_02336) dapD 2200713..2201411 (+) 699 WP_017768831.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase -
  CKV85_RS10945 (SAMEA4504048_02337) - 2201466..2202596 (+) 1131 WP_095123609.1 N-acetyldiaminopimelate deacetylase -
  CKV85_RS10950 (SAMEA4504048_02338) spx 2202649..2203047 (-) 399 WP_017768833.1 transcriptional regulator Spx -
  CKV85_RS10955 (SAMEA4504048_02339) recA 2203285..2204445 (-) 1161 WP_029691479.1 recombinase RecA Machinery gene
  CKV85_RS10960 (SAMEA4504048_02340) cinA 2204542..2205798 (-) 1257 WP_095123610.1 competence/damage-inducible protein A Machinery gene
  CKV85_RS12345 (SAMEA4504048_02341) - 2205961..2207581 (+) 1621 Protein_2143 ATP-binding cassette domain-containing protein -
  CKV85_RS10970 (SAMEA4504048_02343) - 2207652..2208656 (+) 1005 WP_095123611.1 IS5 family transposase -
  CKV85_RS10975 (SAMEA4504048_02344) - 2208772..2209068 (+) 297 Protein_2145 FtsX-like permease family protein -
  CKV85_RS10985 (SAMEA4504048_02347) - 2210181..2210732 (-) 552 WP_095123614.1 DNA-3-methyladenine glycosylase I -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44633.67 Da        Isoelectric Point: 4.6304

>NTDB_id=1147518 CKV85_RS10960 WP_095123610.1 2204542..2205798(-) (cinA) [Streptococcus acidominimus strain NCTC11291]
MKAELIAVGTEILTGQIVNTNAQYLSEKMAEIGVDVYFQTAVGDNEDRLKTVIDQASKRSDLVILCGGLGPTEDDLTKQT
LATYLGRDLVFDPGAEEKLSAFFETRPQYARTPNNERQAQIIEGSIPIPNITGLAVGGLVSVDGVTYVVLPGPPSELKPM
VQESLVPLLSKSGERLYSRVLRFFGIGESQLVTVLANLIAQQTDPTLAPYAKTGEVTLRLSTKAPNQAVADAKLDALEQQ
ILRTDGLDGVPLQTSLYGYGEDNSLSQVTVELLKDKHQSLTAAESLTAGLFQSRIADVAGASQVFQGGFVTYSLEQKAAM
LGISEEDLHTHGVVSDFTARAMAEAAREKVGSDLAVSLTGVAGPDELEGQPVGTVFIALASSKGTEVRKVHIGGRSRSDI
RQIAVLHALNLVRQTLLT

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1147518 CKV85_RS10960 WP_095123610.1 2204542..2205798(-) (cinA) [Streptococcus acidominimus strain NCTC11291]
ATGAAAGCAGAGCTTATCGCCGTTGGCACAGAGATCTTAACAGGTCAAATCGTGAATACCAATGCGCAATACCTGTCCGA
AAAAATGGCAGAAATCGGTGTGGATGTCTATTTTCAAACGGCTGTTGGAGATAATGAGGATCGCTTGAAGACTGTTATTG
ATCAGGCTTCTAAACGCAGTGATTTGGTGATCTTATGCGGGGGGCTAGGGCCGACCGAAGATGACTTAACCAAACAAACC
CTTGCAACCTATCTTGGTCGTGATTTAGTATTTGATCCGGGTGCAGAAGAAAAGCTATCTGCTTTCTTTGAGACACGTCC
TCAATATGCTAGAACGCCAAATAATGAACGCCAGGCGCAGATCATTGAAGGGTCAATTCCCATTCCTAATATCACCGGTT
TAGCCGTAGGTGGTTTGGTCAGTGTTGATGGTGTGACTTACGTGGTTTTACCAGGACCTCCTAGTGAACTCAAGCCGATG
GTTCAAGAAAGCCTTGTTCCCTTACTATCAAAGAGTGGTGAGCGATTGTATTCACGCGTGTTACGTTTCTTTGGTATTGG
TGAAAGTCAGTTGGTGACCGTTTTAGCTAACCTGATTGCACAACAGACAGATCCGACGTTGGCACCTTATGCTAAAACAG
GTGAAGTGACTTTGCGTTTATCGACTAAAGCTCCGAATCAGGCAGTTGCGGATGCGAAACTGGATGCTCTCGAGCAGCAG
ATTTTAAGAACTGACGGCCTAGATGGTGTGCCATTACAAACCTCTTTATATGGCTATGGCGAGGACAATTCCTTGTCACA
AGTGACGGTTGAGTTGCTAAAAGATAAGCATCAGTCACTTACAGCGGCTGAAAGTTTAACAGCTGGCCTTTTTCAATCAA
GGATTGCTGATGTGGCTGGTGCATCTCAGGTTTTTCAAGGTGGGTTTGTGACCTATAGTTTGGAACAAAAAGCAGCAATG
CTAGGCATTTCAGAGGAAGATTTACACACTCATGGTGTTGTGAGTGATTTTACTGCAAGAGCTATGGCAGAAGCGGCGCG
TGAAAAAGTTGGTTCAGACTTGGCAGTCTCTTTAACAGGTGTTGCAGGTCCAGATGAGCTGGAGGGTCAGCCAGTCGGTA
CGGTCTTTATTGCCTTAGCTAGCTCCAAAGGCACTGAGGTGAGAAAGGTGCATATCGGTGGCCGCAGTCGATCGGATATT
CGTCAAATTGCAGTCTTACATGCCTTGAATTTGGTTAGACAAACACTGTTGACATGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-242)

Competence-damaged protein (CinA)

(263-416)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

70.096

100

0.701
  cinA Streptococcus mitis NCTC 12261

69.617

100

0.696
  cinA Streptococcus pneumoniae TIGR4

69.617

100

0.696
  cinA Streptococcus mitis SK321

69.617

100

0.696
  cinA Streptococcus pneumoniae Rx1

69.378

100

0.694
  cinA Streptococcus pneumoniae R6

69.378

100

0.694
  cinA Streptococcus pneumoniae D39

69.139

100

0.691
  cinA Streptococcus suis isolate S10

54.327

99.522

0.541
  cinA Bacillus subtilis subsp. subtilis str. 168

45.215

100

0.452

Multiple sequence alignment