Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   CKV85_RS08295 Genome accession   NZ_LT906454
Coordinates   1713844..1714518 (-) Length   224 a.a.
NCBI ID   WP_095123270.1    Uniprot ID   -
Organism   Streptococcus acidominimus strain NCTC11291     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1714861..1718353 1713844..1714518 flank 343


Gene organization within MGE regions


Location: 1713844..1718353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV85_RS08295 (SAMEA4504048_01762) comEA/celA/cilE 1713844..1714518 (-) 675 WP_095123270.1 helix-hairpin-helix domain-containing protein Machinery gene
  CKV85_RS12270 - 1714669..1714794 (+) 126 WP_269457185.1 hypothetical protein -
  CKV85_RS08300 - 1714861..1715675 (+) 815 Protein_1648 IS5 family transposase -
  CKV85_RS08305 (SAMEA4504048_01765) - 1716088..1716951 (+) 864 WP_095123272.1 IS982 family transposase -
  CKV85_RS08310 (SAMEA4504048_01768) - 1717349..1718353 (-) 1005 WP_095123273.1 IS5 family transposase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 24154.26 Da        Isoelectric Point: 4.3532

>NTDB_id=1147496 CKV85_RS08295 WP_095123270.1 1713844..1714518(-) (comEA/celA/cilE) [Streptococcus acidominimus strain NCTC11291]
MLEDILEKIREYKLIAGLTLVILTLLVVCSFLVVNGSQKEPESTLPSWSKEVSSDSDTAISSEEVKKKQAKEQDTDVITV
DVKGAVKKPGVYQLPDKSRVNEAVLLAGGVTEEADRKSVNFAQKLTDEAVIYVASQGEDISVVPKDPAVLANEPAASSVS
DKINLNTATLTDLQTISGIGQKRAQDILDYRDSSGGFKSVEDLSNVSGIGEKTLEKLREEVTVD

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1147496 CKV85_RS08295 WP_095123270.1 1713844..1714518(-) (comEA/celA/cilE) [Streptococcus acidominimus strain NCTC11291]
ATGCTTGAGGACATTTTAGAGAAAATTCGTGAGTATAAACTCATTGCTGGTTTAACGCTTGTTATTTTGACCTTATTGGT
GGTGTGTAGTTTTCTTGTGGTCAATGGTTCACAAAAAGAACCAGAAAGTACGCTGCCATCGTGGTCAAAAGAGGTGTCAT
CTGATAGCGACACAGCTATTTCTTCAGAAGAAGTCAAAAAGAAGCAGGCGAAAGAGCAAGATACTGATGTTATCACTGTG
GATGTGAAAGGGGCTGTCAAAAAGCCTGGTGTTTATCAGTTGCCAGATAAAAGTCGTGTGAACGAGGCTGTTCTTTTAGC
GGGTGGTGTGACAGAAGAGGCAGACCGTAAATCAGTTAATTTTGCTCAAAAACTAACCGATGAGGCAGTGATTTATGTTG
CAAGCCAAGGGGAAGATATCTCAGTTGTTCCTAAAGATCCAGCTGTTTTAGCAAATGAACCAGCTGCTTCTTCAGTGTCA
GATAAGATTAATCTCAATACAGCGACGCTTACGGACTTACAAACTATTTCTGGGATCGGTCAAAAGAGGGCGCAAGATAT
TTTAGATTATCGTGATAGCAGTGGTGGGTTTAAATCTGTCGAGGATTTATCCAATGTTTCCGGTATCGGTGAAAAGACTC
TAGAGAAGCTGCGTGAGGAAGTAACCGTTGATTAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(161-222)

SLBB domain (SLBB)

(80-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

47.162

100

0.482
  comEA/celA/cilE Streptococcus pneumoniae R6

47.162

100

0.482
  comEA/celA/cilE Streptococcus pneumoniae D39

47.162

100

0.482
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

47.137

100

0.478
  comEA/celA/cilE Streptococcus mitis NCTC 12261

46.696

100

0.473
  comEA/celA/cilE Streptococcus mitis SK321

46.696

100

0.473
  comEA Streptococcus thermophilus LMD-9

41.81

100

0.433
  comEA Lactococcus lactis subsp. cremoris KW2

41.558

100

0.429
  comEA Latilactobacillus sakei subsp. sakei 23K

33.065

100

0.366

Multiple sequence alignment