Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   BQ8897_RS10855 Genome accession   NZ_LT714196
Coordinates   2065008..2066267 (-) Length   419 a.a.
NCBI ID   WP_001200982.1    Uniprot ID   -
Organism   Streptococcus agalactiae isolate BM110     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2058895..2093046 2065008..2066267 within 0


Gene organization within MGE regions


Location: 2058895..2093046
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BQ8897_RS10820 (BQ8897_BM110_02130) - 2060159..2061700 (-) 1542 WP_000230034.1 hypothetical protein -
  BQ8897_RS11905 (BQ8897_BM110_02131) - 2061746..2061868 (-) 123 WP_001285712.1 hypothetical protein -
  BQ8897_RS10830 (BQ8897_BM110_02132) - 2061951..2062268 (-) 318 WP_000940933.1 DUF1292 domain-containing protein -
  BQ8897_RS10835 (BQ8897_BM110_02133) ruvX 2062294..2062713 (-) 420 WP_001873911.1 Holliday junction resolvase RuvX -
  BQ8897_RS10840 (BQ8897_BM110_02134) - 2062713..2062979 (-) 267 WP_000507056.1 IreB family regulatory phosphoprotein -
  BQ8897_RS10845 (BQ8897_BM110_02135) spx 2063181..2063579 (-) 399 WP_000591161.1 transcriptional regulator Spx -
  BQ8897_RS10850 (BQ8897_BM110_02136) recA 2063795..2064934 (-) 1140 WP_001085741.1 recombinase RecA Machinery gene
  BQ8897_RS10855 (BQ8897_BM110_02137) cinA 2065008..2066267 (-) 1260 WP_001200982.1 competence/damage-inducible protein A Machinery gene
  BQ8897_RS10860 (BQ8897_BM110_02138) - 2066356..2066907 (-) 552 WP_000817340.1 DNA-3-methyladenine glycosylase I -
  BQ8897_RS10865 (BQ8897_BM110_02139) ruvA 2066930..2067520 (-) 591 WP_000272489.1 Holliday junction branch migration protein RuvA -
  BQ8897_RS10870 (BQ8897_BM110_02140) - 2067522..2068754 (-) 1233 WP_000657474.1 MDR family MFS transporter -
  BQ8897_RS10875 (BQ8897_BM110_02141) mutL 2068786..2070759 (-) 1974 WP_000034615.1 DNA mismatch repair endonuclease MutL -
  BQ8897_RS10885 (BQ8897_BM110_02142) - 2070985..2071188 (+) 204 WP_000191849.1 cold-shock protein -
  BQ8897_RS10890 (BQ8897_BM110_02143) mutS 2071245..2073821 (-) 2577 WP_001118373.1 DNA mismatch repair protein MutS -
  BQ8897_RS10895 (BQ8897_BM110_02144) argR 2073878..2074315 (-) 438 WP_001033152.1 arginine repressor -
  BQ8897_RS10900 (BQ8897_BM110_02145) argS 2074537..2076228 (+) 1692 WP_000379872.1 arginine--tRNA ligase -
  BQ8897_RS10905 (BQ8897_BM110_02146) - 2076316..2076624 (+) 309 WP_001138859.1 bacteriocin immunity protein -
  BQ8897_RS10910 (BQ8897_BM110_02147) - 2076651..2077523 (-) 873 WP_000915474.1 YitT family protein -
  BQ8897_RS10915 (BQ8897_BM110_02148) - 2077631..2078575 (-) 945 WP_000857770.1 YitT family protein -
  BQ8897_RS10920 (BQ8897_BM110_02149) aspS 2078565..2080316 (-) 1752 WP_000830928.1 aspartate--tRNA ligase -
  BQ8897_RS10925 (BQ8897_BM110_02150) hisS 2080409..2081689 (-) 1281 WP_000775911.1 histidine--tRNA ligase -
  BQ8897_RS10930 (BQ8897_BM110_02151) rpmF 2081909..2082091 (+) 183 WP_000290414.1 50S ribosomal protein L32 -
  BQ8897_RS10935 (BQ8897_BM110_02152) rpmG 2082107..2082256 (+) 150 WP_001265622.1 50S ribosomal protein L33 -
  BQ8897_RS11855 - 2082335..2082519 (-) 185 Protein_2058 FanG protein -
  BQ8897_RS10945 (BQ8897_BM110_02153) - 2082548..2083162 (+) 615 WP_000615736.1 CadD family cadmium resistance transporter -
  BQ8897_RS10950 (BQ8897_BM110_02154) cadX 2083174..2083512 (+) 339 WP_000711078.1 Cd(II)/Zn(II)-sensing metalloregulatory transcriptional regulator CadX -
  BQ8897_RS10955 (BQ8897_BM110_02155) - 2083563..2084978 (+) 1416 WP_000667640.1 helix-turn-helix domain-containing protein -
  BQ8897_RS10960 (BQ8897_BM110_02156) - 2085299..2085748 (+) 450 WP_000066889.1 RNA polymerase sigma factor -
  BQ8897_RS10965 (BQ8897_BM110_02157) - 2085950..2086270 (+) 321 WP_000874694.1 hypothetical protein -
  BQ8897_RS10970 (BQ8897_BM110_02158) - 2086270..2087370 (+) 1101 WP_000203865.1 type IV secretion system DNA-binding domain-containing protein -
  BQ8897_RS10975 (BQ8897_BM110_02159) - 2087367..2087972 (+) 606 WP_000182709.1 hypothetical protein -
  BQ8897_RS10980 (BQ8897_BM110_02160) - 2088178..2088783 (+) 606 WP_001040935.1 replication protein -
  BQ8897_RS10985 (BQ8897_BM110_02161) - 2088776..2089024 (+) 249 WP_001058391.1 MerR family transcriptional regulator -
  BQ8897_RS10990 (BQ8897_BM110_02162) - 2089114..2090379 (+) 1266 WP_000447185.1 tyrosine-type recombinase/integrase -
  BQ8897_RS10995 (BQ8897_BM110_02163) - 2090810..2091799 (+) 990 WP_001873912.1 TerB N-terminal domain-containing protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45485.36 Da        Isoelectric Point: 6.3060

>NTDB_id=1146180 BQ8897_RS10855 WP_001200982.1 2065008..2066267(-) (cinA) [Streptococcus agalactiae isolate BM110]
MRAEIIAVGTEILTGQIVNTNAQFLSEKMAELGIDIYFQTAVGDNEERLLSLLDIASQRSQMVILCGGLGPTEDDLTKQT
LAKFLGKSLTVDLLASQKLDRFFASRPQFARTPNNERQAQLVEGSIPLQNLTGLAVGGIVTSKGVQYMVLPGPPSELKPM
VMEQVVPILSNNGTKLYSRVLRFFGIGESQLVTILEDIIKNQTDPTIAPYAKIGEVTLRLSTKAENQNEADFKLDSLEKE
ILALKTLDNRKLKDLLYGYGDNNSMARTVLELLKVQNKTITAAESLTAGLFQSQLAEFSGASQVFNGGFTTYSMEAKSQL
LGIPKKKLQEYGVVSHFTAEAMAQQARQLLKADFGIGLTGVAGPDELEGYPAGTVFIGIATPEGVSSIKVSIGGKSRSDV
RHISTLHAFDLVRRALLKI

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=1146180 BQ8897_RS10855 WP_001200982.1 2065008..2066267(-) (cinA) [Streptococcus agalactiae isolate BM110]
GTGAGGGCTGAAATTATCGCTGTAGGAACAGAAATTTTAACAGGACAGATCGTTAATACAAACGCACAATTTTTGTCGGA
GAAAATGGCAGAATTGGGAATTGATATTTATTTCCAGACAGCTGTAGGAGATAATGAGGAACGTTTATTATCGCTTTTAG
ATATAGCTAGTCAGCGCAGTCAAATGGTTATCCTATGTGGTGGACTTGGACCTACAGAGGATGATTTAACGAAACAAACT
TTGGCTAAATTTTTAGGTAAATCATTAACAGTGGATTTATTAGCTAGTCAAAAATTGGATCGTTTTTTTGCAAGTCGTCC
TCAGTTTGCTAGAACGCCAAATAATGAACGACAAGCTCAATTGGTTGAAGGCTCAATACCTCTACAAAACCTTACTGGTC
TAGCTGTTGGTGGTATCGTTACATCTAAGGGAGTCCAATATATGGTTTTACCAGGTCCGCCTAGTGAATTAAAGCCAATG
GTTATGGAGCAGGTGGTACCTATTTTGTCAAATAATGGCACAAAATTATATTCACGTGTATTGAGATTCTTTGGTATCGG
TGAGAGTCAGTTAGTCACAATCTTAGAAGACATAATTAAGAATCAGACAGATCCAACTATAGCACCATATGCAAAGATTG
GTGAGGTAACTTTAAGGTTATCAACGAAAGCTGAAAATCAGAATGAAGCCGACTTTAAATTAGATAGCTTAGAAAAAGAA
ATACTTGCTCTTAAGACATTAGATAACCGTAAATTAAAAGATTTATTATATGGCTATGGTGATAATAATAGTATGGCACG
TACTGTTTTAGAATTATTGAAAGTACAAAATAAAACGATTACTGCCGCAGAGAGCTTAACAGCAGGGTTATTTCAATCTC
AGTTAGCAGAATTTTCTGGTGCTTCGCAAGTTTTTAATGGTGGCTTTACGACCTATAGTATGGAAGCAAAATCACAACTT
CTCGGCATCCCTAAGAAAAAATTGCAAGAATATGGAGTTGTCAGTCATTTTACAGCTGAGGCAATGGCTCAGCAAGCTCG
CCAGCTTTTAAAAGCAGATTTTGGTATCGGTTTAACGGGAGTTGCTGGTCCTGATGAGTTGGAAGGATACCCTGCAGGTA
CAGTTTTTATTGGGATTGCAACCCCTGAAGGCGTTTCTTCTATTAAAGTATCGATTGGAGGGAAGAGCCGCTCAGATGTC
CGTCATATCAGTACTTTACATGCTTTTGACCTGGTGCGTAGGGCTTTATTAAAGATATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

71.463

99.523

0.711
  cinA Streptococcus mitis NCTC 12261

71.223

99.523

0.709
  cinA Streptococcus pneumoniae TIGR4

70.024

99.523

0.697
  cinA Streptococcus pneumoniae Rx1

70.024

99.523

0.697
  cinA Streptococcus pneumoniae R6

70.024

99.523

0.697
  cinA Streptococcus pneumoniae D39

69.784

99.523

0.695
  cinA Streptococcus mutans UA159

68.106

99.523

0.678
  cinA Streptococcus suis isolate S10

54.808

99.284

0.544
  cinA Bacillus subtilis subsp. subtilis str. 168

43.78

99.761

0.437

Multiple sequence alignment