Detailed information NTG1143388

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: PA5486_RS28425
• Genome accession: NZ_LS998783
• Coordinates: 5804816..5806075 (+)
• Length: 419 a.a.
• NCBI ID: WP_134163279.1
• Uniprot ID: -
• Organism: Pseudomonas aeruginosa isolate
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	5803822..5804838	5804816..5806075	flank	-22

Gene organization within MGE regions

Location: 5803822..5806075

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PA5486_RS28420 (PA5486_05525)	-	5803822..5804838 (+)	1017	WP_032728035.1	IS30-like element IS1394 family transposase	-
PA5486_RS28425 (PA5486_05526)	pilC	5804816..5806075 (+)	1260	WP_134163279.1	type II secretion system F family protein	Machinery gene

Sequence

Protein

• Length: 419 a.a.
• Molecular weight: 45665.79 Da
• Isoelectric Point: 9.9077

>NTDB_id=1143388 PA5486_RS28425 WP_134163279.1 5804816..5806075(+) (pilC) [Pseudomonas aeruginosa isolate]
MHLLQSSNRVALSFCNRQALKTSVFVWEGTDKKGTKVKGELSSQNPTLVKAQLRKQGITPVKVRKKGISLLGAGKKIKPM
DIALFTRQMSTMMAAGVPLLQSFDIISEGFDNPNMRKLVEEIKQEVAGGNSLANSLRKKPQYFDSLYCNLVDAGEQSGAL
ETLLDRVATYKEKTEALKAKIKKAMTYPIAVIVVAIIVSAILLIKVVPQFQSVFEGFGAELPAFTMMVINISNVLQEWWL
LVLLMMGGAGFLLNHAYKRSEKFRDATDRTVLKLPIVGAILYKSAVARYARTLSTTFAAGVPLVEALDSVSGATGNVVFR
DAVGKIKQDVSTGMQLNFSMRTTHIFPSMAIQMTAIGEESGALDDMLAKVAGFYEQEVDNAVDNLTALMEPMIMAVLGVL
VGGLIIAMYLPIFQLGNVV

Nucleotide

• Length: 1260 bp

>NTDB_id=1143388 PA5486_RS28425 WP_134163279.1 5804816..5806075(+) (pilC) [Pseudomonas aeruginosa isolate]
ATGCACCTGCTTCAATCCAGTAACCGTGTTGCACTCAGCTTCTGCAACCGCCAAGCGTTAAAGACCAGTGTCTTCGTATG
GGAAGGCACTGACAAGAAAGGCACCAAGGTCAAGGGCGAGCTGTCCAGCCAGAACCCGACCCTGGTCAAGGCGCAACTGC
GCAAGCAGGGCATCACGCCGGTCAAGGTCCGCAAGAAAGGCATCTCCCTGCTGGGGGCGGGGAAGAAGATCAAGCCTATG
GACATCGCCCTGTTCACCCGCCAGATGTCCACCATGATGGCCGCCGGCGTGCCGCTGCTGCAGTCGTTCGACATCATCAG
CGAAGGCTTCGACAATCCGAACATGCGCAAGCTGGTGGAGGAGATCAAGCAGGAAGTCGCCGGCGGCAACAGCCTGGCCA
ACTCGCTGCGCAAGAAGCCGCAGTACTTCGACTCGCTCTACTGCAACCTGGTGGACGCCGGCGAACAATCCGGCGCCCTG
GAAACCCTGCTCGACCGGGTCGCCACCTACAAGGAAAAGACCGAGGCGCTGAAGGCCAAGATCAAGAAGGCCATGACCTA
CCCGATCGCGGTGATCGTCGTCGCCATCATCGTTTCGGCGATCCTACTGATCAAGGTGGTGCCGCAGTTCCAGTCGGTGT
TCGAGGGCTTCGGCGCCGAACTGCCAGCCTTCACCATGATGGTCATCAACATTTCCAACGTACTCCAGGAATGGTGGCTC
CTGGTACTGCTGATGATGGGCGGCGCCGGCTTCCTGCTGAACCACGCCTACAAGCGTTCGGAGAAGTTCCGCGACGCCAC
CGACCGCACGGTACTGAAGCTGCCTATCGTCGGCGCCATCCTCTACAAATCCGCCGTGGCACGCTACGCGCGGACGCTGT
CGACCACCTTCGCCGCCGGCGTGCCATTGGTGGAAGCCCTCGACTCGGTTTCCGGCGCCACCGGCAACGTGGTGTTCAGG
GACGCGGTGGGCAAGATCAAGCAGGACGTGTCCACCGGCATGCAGCTGAACTTCTCCATGCGCACCACCCACATCTTCCC
CAGCATGGCCATCCAGATGACCGCCATCGGCGAGGAGTCGGGCGCGCTGGACGACATGCTGGCCAAGGTCGCTGGCTTCT
ACGAGCAGGAAGTGGATAATGCCGTGGACAACCTGACCGCCCTGATGGAACCGATGATCATGGCGGTCCTCGGGGTCCTG
GTCGGTGGCCTGATCATCGCCATGTACCTGCCGATCTTCCAGCTGGGCAACGTCGTCTAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (85-208)

• Type II secretion system (T2SS), protein F (T2SSF) (290-411)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Pseudomonas stutzeri DSM 10701	78.412	96.181	0.754
pilC	Acinetobacter baylyi ADP1	61.5	95.465	0.587
pilC	Acinetobacter baumannii D1279779	59.753	96.659	0.578
pilC	Legionella pneumophila strain ERS1305867	54.545	94.511	0.516
pilG	Neisseria gonorrhoeae MS11	46.04	96.42	0.444
pilG	Neisseria meningitidis 44/76-A	45.522	95.943	0.437
pilC	Vibrio cholerae strain A1552	41.687	96.181	0.401
pilC	Vibrio campbellii strain DS40M4	40.852	95.227	0.389
pilC	Thermus thermophilus HB27	38.155	95.704	0.365