Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   DQL19_RS03160 Genome accession   NZ_LS483480
Coordinates   611036..612373 (+) Length   445 a.a.
NCBI ID   WP_015701646.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC13377     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 606036..617373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL19_RS03135 (NCTC13377_00612) - 606101..608695 (-) 2595 WP_077643690.1 penicillin-binding protein 1A -
  DQL19_RS03140 (NCTC13377_00613) comA 608794..609591 (+) 798 WP_005693722.1 competence protein A Machinery gene
  DQL19_RS03145 (NCTC13377_00614) comB 609592..610098 (+) 507 WP_011272049.1 competence protein ComB Machinery gene
  DQL19_RS03150 (NCTC13377_00615) comC 610095..610616 (+) 522 WP_077643691.1 competence protein ComC Machinery gene
  DQL19_RS03155 (NCTC13377_00616) comD 610613..611026 (+) 414 WP_015701647.1 pilus assembly protein PilP Machinery gene
  DQL19_RS03160 (NCTC13377_00617) comE 611036..612373 (+) 1338 WP_015701646.1 type IV pilus secretin PilQ family protein Machinery gene
  DQL19_RS03165 (NCTC13377_00618) - 612386..613072 (+) 687 WP_015701645.1 ComF family protein -
  DQL19_RS03170 (NCTC13377_00619) nfuA 613148..613744 (+) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  DQL19_RS03175 (NCTC13377_00620) nudC 613811..614605 (+) 795 WP_015701644.1 NAD(+) diphosphatase -
  DQL19_RS03180 (NCTC13377_00621) - 614641..615231 (+) 591 WP_015701643.1 YjaG family protein -
  DQL19_RS03185 (NCTC13377_00622) - 615371..615643 (+) 273 WP_005630954.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49207.47 Da        Isoelectric Point: 7.8816

>NTDB_id=1142486 DQL19_RS03160 WP_015701646.1 611036..612373(+) (comE) [Haemophilus influenzae strain NCTC13377]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQHDVNLVMGERLEGNISLKLNNIDMPRLLK
IIAKSKHLTLNKDDGVYYLNGSQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSPDGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PIIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=1142486 DQL19_RS03160 WP_015701646.1 611036..612373(+) (comE) [Haemophilus influenzae strain NCTC13377]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTGTGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACACTAGAGCAATTAGCTTTTCAACATGATG
TCAATTTAGTGATGGGTGAGAGGTTAGAAGGCAATATTTCTTTGAAATTAAACAATATTGATATGCCACGTTTGCTAAAA
ATAATCGCAAAAAGTAAGCATCTTACTTTGAATAAAGATGATGGAGTTTATTATTTAAACGGCAGCCAATCTGGCAAAGG
TCAAGTTGCAGGAAATCTTACGACAAATGAACCACACTTAGTGAGTCACACGGTAAAACTTCATTTTGCTAAAGCCTCTG
AATTAATGAAATCCTTAACAACAGGAAGTGGATCTTTGCTTTCTCCCGATGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTTGCCAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGGACAGAAATTCCTTACATCGTGAGTAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCGGTG
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCATTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTGACGCCACATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGGAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(269-429)

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

98.652

100

0.987
  comE Haemophilus influenzae Rd KW20

97.528

100

0.975
  comE Glaesserella parasuis strain SC1401

52

95.506

0.497
  pilQ Vibrio campbellii strain DS40M4

42.959

94.157

0.404
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.99

92.584

0.389
  pilQ Vibrio cholerae strain A1552

41.99

92.584

0.389

Multiple sequence alignment