Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   DQN71_RS07370 Genome accession   NZ_LS483471
Coordinates   1405748..1406440 (-) Length   230 a.a.
NCBI ID   WP_015605401.1    Uniprot ID   A0A512AB75
Organism   Streptococcus cristatus strain NCTC13807     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1400748..1411440
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN71_RS07350 (NCTC13807_01412) - 1400776..1401765 (-) 990 WP_015605397.1 anti sigma factor C-terminal domain-containing protein -
  DQN71_RS07355 (NCTC13807_01413) - 1401752..1402222 (-) 471 WP_172456459.1 RNA polymerase sigma factor -
  DQN71_RS07360 (NCTC13807_01414) - 1402506..1403420 (-) 915 WP_015605399.1 DUF805 domain-containing protein -
  DQN71_RS07365 (NCTC13807_01415) comEC/celB 1403527..1405767 (-) 2241 WP_015605400.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DQN71_RS07370 (NCTC13807_01416) comEA/celA/cilE 1405748..1406440 (-) 693 WP_015605401.1 helix-hairpin-helix domain-containing protein Machinery gene
  DQN71_RS07375 (NCTC13807_01417) - 1406717..1407457 (-) 741 WP_015605402.1 lysophospholipid acyltransferase family protein -
  DQN71_RS07380 (NCTC13807_01418) - 1407614..1409953 (+) 2340 WP_015605403.1 cation-translocating P-type ATPase -
  DQN71_RS07385 (NCTC13807_01419) - 1410046..1410792 (+) 747 WP_015605404.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  DQN71_RS07390 (NCTC13807_01420) - 1410782..1411045 (+) 264 WP_015605405.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 24534.58 Da        Isoelectric Point: 4.9200

>NTDB_id=1142321 DQN71_RS07370 WP_015605401.1 1405748..1406440(-) (comEA/celA/cilE) [Streptococcus cristatus strain NCTC13807]
MFEEILEKLKEYKIFVGLSLIGVVLAGLFLLKGNAQPQNQVSALAQEVVTSASSETNAEKRSANQEKISEKNIDSEESEK
EVTVDVKGAVKNPGVYQLRAGARVHDALQKAGGLLPDAESKSINQAQKLTDEAVVYVARVGEEGADVTQDSQTPAGNGET
AKGKSGLVNLNTATEAELQTVSGIGQKKAQDIIAYREANGKFKSVDELKNVSGIGAKTLEKLKDYVTVDK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=1142321 DQN71_RS07370 WP_015605401.1 1405748..1406440(-) (comEA/celA/cilE) [Streptococcus cristatus strain NCTC13807]
ATGTTTGAAGAAATACTTGAAAAATTAAAGGAATACAAGATTTTTGTTGGGCTTTCTTTGATAGGAGTCGTCTTGGCTGG
GCTTTTCTTGCTGAAGGGCAACGCTCAGCCACAGAATCAAGTCAGTGCACTGGCTCAGGAAGTGGTTACATCAGCTTCAT
CTGAAACCAATGCAGAAAAAAGAAGTGCGAATCAAGAAAAAATCTCAGAAAAAAATATAGATTCGGAGGAATCTGAGAAA
GAAGTCACCGTTGATGTCAAAGGAGCTGTCAAAAATCCAGGAGTTTATCAGTTGCGGGCAGGAGCGCGTGTACACGATGC
CTTACAAAAAGCAGGTGGTCTACTGCCAGATGCCGAGTCAAAATCCATCAACCAAGCTCAAAAATTAACAGATGAGGCGG
TTGTTTATGTAGCTAGAGTCGGTGAGGAAGGGGCAGATGTGACACAAGATAGTCAGACGCCCGCTGGAAATGGAGAAACG
GCAAAAGGGAAGTCTGGCTTGGTCAATCTCAATACGGCGACCGAAGCTGAACTTCAGACCGTTTCAGGCATCGGTCAAAA
GAAAGCGCAAGACATCATCGCTTATCGGGAAGCCAATGGCAAGTTTAAGTCAGTAGATGAGCTGAAAAATGTTTCAGGAA
TTGGTGCAAAAACTTTAGAAAAGTTAAAAGACTATGTCACAGTGGATAAATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(165-227)

SLBB domain (SLBB)

(84-137)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A512AB75

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

51.965

99.565

0.517
  comEA/celA/cilE Streptococcus mitis NCTC 12261

51.528

99.565

0.513
  comEA/celA/cilE Streptococcus pneumoniae R6

49.787

100

0.509
  comEA/celA/cilE Streptococcus pneumoniae Rx1

49.787

100

0.509
  comEA/celA/cilE Streptococcus pneumoniae D39

49.787

100

0.509
  comEA/celA/cilE Streptococcus mitis SK321

50.655

99.565

0.504
  comEA Streptococcus thermophilus LMD-9

44.206

100

0.448
  comEA Lactococcus lactis subsp. cremoris KW2

40

100

0.4
  comEA Staphylococcus aureus N315

35.931

100

0.361

Multiple sequence alignment