Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   DQK98_RS02650 Genome accession   NZ_LS483449
Coordinates   503493..505169 (-) Length   558 a.a.
NCBI ID   WP_196299874.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836170     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 498493..510169
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQK98_RS02620 - 498825..499154 (-) 330 WP_000132572.1 hypothetical protein -
  DQK98_RS02625 - 499431..499769 (+) 339 WP_000682132.1 LytTR family DNA-binding domain-containing protein -
  DQK98_RS02630 comE/blpR 499774..500511 (+) 738 WP_001219146.1 response regulator transcription factor Regulator
  DQK98_RS02635 - 500525..501865 (+) 1341 WP_001099895.1 sensor histidine kinase -
  DQK98_RS02640 blpC 501909..502064 (-) 156 WP_044791640.1 quorum-sensing system pheromone BlpC -
  DQK98_RS02645 - 502121..503482 (-) 1362 Protein_504 bacteriocin secretion accessory protein -
  DQK98_RS02650 comA/nlmT 503493..505169 (-) 1677 WP_196299874.1 peptide cleavage/export ABC transporter Regulator
  DQK98_RS12195 comA/nlmT 505063..505650 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  DQK98_RS02655 blpM 505932..506186 (+) 255 WP_001093256.1 two-peptide bacteriocin subunit BlpM -
  DQK98_RS02660 blpN 506202..506405 (+) 204 WP_001099490.1 two-peptide bacteriocin subunit BlpN -
  DQK98_RS02670 cipB 506649..506798 (+) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  DQK98_RS02675 - 506902..507021 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  DQK98_RS02680 - 507319..507483 (+) 165 WP_000727117.1 hypothetical protein -
  DQK98_RS02685 - 507545..507883 (+) 339 WP_088804618.1 immunity protein -
  DQK98_RS02695 - 508512..508895 (+) 384 WP_000877381.1 hypothetical protein -
  DQK98_RS02700 - 508947..509636 (+) 690 WP_000760520.1 CPBP family intramembrane glutamic endopeptidase -
  DQK98_RS02705 blpZ 509678..509926 (+) 249 WP_000276501.1 immunity protein BlpZ -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62923.20 Da        Isoelectric Point: 6.7844

>NTDB_id=1141889 DQK98_RS02650 WP_196299874.1 503493..505169(-) (comA/nlmT) [Streptococcus pneumoniae strain 4041STDY6836170]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=1141889 DQK98_RS02650 WP_196299874.1 503493..505169(-) (comA/nlmT) [Streptococcus pneumoniae strain 4041STDY6836170]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATCGGTGGTTC
TTATTATCTCCAAGGAATCTTGGATGAATACATCCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTTTCCAGAGATTATCTCCTAACTGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGAGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGCCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.89

99.821

0.728
  comA Streptococcus mitis NCTC 12261

67.204

100

0.672
  comA Streptococcus pneumoniae D39

66.846

100

0.668
  comA Streptococcus pneumoniae R6

66.846

100

0.668
  comA Streptococcus pneumoniae Rx1

66.846

100

0.668
  comA Streptococcus mitis SK321

66.667

100

0.667
  comA Streptococcus gordonii str. Challis substr. CH1

66.547

100

0.667
  comA Streptococcus pneumoniae TIGR4

66.487

100

0.665

Multiple sequence alignment