Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   DQK99_RS04885 Genome accession   NZ_LS483448
Coordinates   901165..901815 (+) Length   216 a.a.
NCBI ID   WP_111703785.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836167     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 896165..906815
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQK99_RS04840 - 896648..896863 (+) 216 WP_001232081.1 YozE family protein -
  DQK99_RS04845 - 896949..897917 (+) 969 WP_000658183.1 PhoH family protein -
  DQK99_RS04855 - 898110..898610 (+) 501 WP_000566988.1 GNAT family N-acetyltransferase -
  DQK99_RS04860 - 898613..898939 (+) 327 Protein_927 TfoX/Sxy family protein -
  DQK99_RS12270 ald 899240..900351 (-) 1112 Protein_928 alanine dehydrogenase -
  DQK99_RS04880 - 900528..901097 (+) 570 WP_000443772.1 GNAT family N-acetyltransferase -
  DQK99_RS04885 comEA/celA/cilE 901165..901815 (+) 651 WP_111703785.1 helix-hairpin-helix domain-containing protein Machinery gene
  DQK99_RS04890 comEC/celB 901799..904039 (+) 2241 WP_000942408.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DQK99_RS04895 - 904218..904406 (+) 189 WP_001810030.1 hypothetical protein -
  DQK99_RS04900 - 904439..905026 (+) 588 WP_000939886.1 ATP-binding cassette domain-containing protein -
  DQK99_RS04905 - 905030..906214 (+) 1185 WP_000655949.1 ABC transporter permease -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23226.61 Da        Isoelectric Point: 5.9204

>NTDB_id=1141819 DQK99_RS04885 WP_111703785.1 901165..901815(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 4041STDY6836167]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLASEKEVNKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVHKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEESVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=1141819 DQK99_RS04885 WP_111703785.1 901165..901815(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 4041STDY6836167]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGCATCCGAAAAGGAAGTGAACAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCATAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAATCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-126)

Helix-hairpin-helix motif (HHH_3)

(151-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

98.611

100

0.986
  comEA/celA/cilE Streptococcus pneumoniae D39

98.611

100

0.986
  comEA/celA/cilE Streptococcus pneumoniae R6

98.611

100

0.986
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

96.296

100

0.963
  comEA/celA/cilE Streptococcus mitis NCTC 12261

94.907

100

0.949
  comEA/celA/cilE Streptococcus mitis SK321

90.278

100

0.903
  comEA Lactococcus lactis subsp. cremoris KW2

43.612

100

0.458
  comEA Bacillus subtilis subsp. subtilis str. 168

41.053

87.963

0.361
  comEA Latilactobacillus sakei subsp. sakei 23K

33.476

100

0.361

Multiple sequence alignment