Detailed information NTG1141820

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: DQK99_RS04890
• Genome accession: NZ_LS483448
• Coordinates: 901799..904039 (+)
• Length: 746 a.a.
• NCBI ID: WP_000942408.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 4041STDY6836167
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 896799..909039

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQK99_RS04845	-	896949..897917 (+)	969	WP_000658183.1	PhoH family protein	-
DQK99_RS04855	-	898110..898610 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
DQK99_RS04860	-	898613..898939 (+)	327	Protein_927	TfoX/Sxy family protein	-
DQK99_RS12270	ald	899240..900351 (-)	1112	Protein_928	alanine dehydrogenase	-
DQK99_RS04880	-	900528..901097 (+)	570	WP_000443772.1	GNAT family N-acetyltransferase	-
DQK99_RS04885	comEA/celA/cilE	901165..901815 (+)	651	WP_111703785.1	helix-hairpin-helix domain-containing protein	Machinery gene
DQK99_RS04890	comEC/celB	901799..904039 (+)	2241	WP_000942408.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DQK99_RS04895	-	904218..904406 (+)	189	WP_001810030.1	hypothetical protein	-
DQK99_RS04900	-	904439..905026 (+)	588	WP_000939886.1	ATP-binding cassette domain-containing protein	-
DQK99_RS04905	-	905030..906214 (+)	1185	WP_000655949.1	ABC transporter permease	-
DQK99_RS04910	infC	906523..907053 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
DQK99_RS04915	rpmI	907086..907286 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
DQK99_RS04920	rplT	907338..907697 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
DQK99_RS04925	-	907755..908135 (+)	381	WP_000157154.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84561.22 Da
• Isoelectric Point: 9.7561

>NTDB_id=1141820 DQK99_RS04890 WP_000942408.1 901799..904039(+) (comEC/celB) [Streptococcus pneumoniae strain 4041STDY6836167]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQVSQN
LVDSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKKIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGYLNTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLISLALVYDLRKNIKGLTVLSLLITGLFFLTK
YPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1141820 DQK99_RS04890 WP_000942408.1 901799..904039(+) (comEC/celB) [Streptococcus pneumoniae strain 4041STDY6836167]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTTTGGCTTTATTACGCTATTTT
CTCAGCATCTTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGTTCTAATAATTTGCGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGTGAGTCAAAAT
TTGGTGGATTCTGTTGAAAGGGTACGGATTTTACCAGACACTATTAAGGTTAACGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAAAAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGATATCTGAACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTAGAGGGCATTATTCGCTTGGT
CTCGCAGGTGGCAAGGAGACCGCTTGTCTTTGGTCAACCCAACGCATGGCTTTTAATCTTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAGGATTAACAGTATTGAGTTTATTGATTACAGGTCTCTTTTTCCTTACCAAG
TATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CACAGAGAAGCTTGATACCCTATCTTAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTGATTTTGACAAATACGGACAAG
GAACATGTCGGAGATTTGTTAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTTTAGTATCAAAAGGCAGTTTGAAGCA
GAAGCAATTTGTGGTAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGACAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCCCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTACCGAACTGACCAGCAAGGAGCTATACGCTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (31-177)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-693)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	97.855	100	0.979
comEC/celB	Streptococcus pneumoniae Rx1	96.783	100	0.968
comEC/celB	Streptococcus pneumoniae D39	96.783	100	0.968
comEC/celB	Streptococcus pneumoniae R6	96.783	100	0.968
comEC/celB	Streptococcus mitis SK321	92.225	100	0.922
comEC/celB	Streptococcus mitis NCTC 12261	91.946	99.866	0.918
comEC	Lactococcus lactis subsp. cremoris KW2	44.534	99.33	0.442