Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   DQK99_RS02875 Genome accession   NZ_LS483448
Coordinates   530361..532037 (-) Length   558 a.a.
NCBI ID   WP_196299874.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836167     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 525361..537037
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQK99_RS02845 - 525695..526024 (-) 330 WP_000132572.1 hypothetical protein -
  DQK99_RS02850 - 526301..526639 (+) 339 WP_000682135.1 LytTR family DNA-binding domain-containing protein -
  DQK99_RS02855 comE/blpR 526644..527381 (+) 738 WP_088794864.1 response regulator transcription factor Regulator
  DQK99_RS02860 - 527395..528735 (+) 1341 WP_001017638.1 sensor histidine kinase -
  DQK99_RS02865 blpC 528777..528932 (-) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  DQK99_RS02870 - 528989..530350 (-) 1362 WP_001069091.1 bacteriocin secretion accessory protein -
  DQK99_RS02875 comA/nlmT 530361..532037 (-) 1677 WP_196299874.1 peptide cleavage/export ABC transporter Regulator
  DQK99_RS12630 comA/nlmT 531931..532518 (-) 588 WP_001810228.1 cysteine peptidase family C39 domain-containing protein Regulator
  DQK99_RS02880 blpI 532800..532997 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  DQK99_RS02890 blpJ 533464..533733 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  DQK99_RS02895 blpU 533802..534032 (+) 231 WP_000379964.1 bacteriocin-like peptide BlpU -
  DQK99_RS02900 - 534035..534154 (+) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  DQK99_RS02905 - 534451..534615 (+) 165 WP_000727118.1 hypothetical protein -
  DQK99_RS02910 - 534612..535016 (+) 405 WP_000846944.1 hypothetical protein -
  DQK99_RS02915 - 535214..536019 (+) 806 Protein_558 IS5 family transposase -
  DQK99_RS02920 blpM 536169..536423 (+) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  DQK99_RS02925 blpN 536439..536642 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  DQK99_RS02935 cipB 536886..537035 (+) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62923.20 Da        Isoelectric Point: 6.7844

>NTDB_id=1141811 DQK99_RS02875 WP_196299874.1 530361..532037(-) (comA/nlmT) [Streptococcus pneumoniae strain 4041STDY6836167]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=1141811 DQK99_RS02875 WP_196299874.1 530361..532037(-) (comA/nlmT) [Streptococcus pneumoniae strain 4041STDY6836167]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTAGATGAATACATCCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGCCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.89

99.821

0.728
  comA Streptococcus mitis NCTC 12261

67.204

100

0.672
  comA Streptococcus pneumoniae D39

66.846

100

0.668
  comA Streptococcus pneumoniae R6

66.846

100

0.668
  comA Streptococcus pneumoniae Rx1

66.846

100

0.668
  comA Streptococcus mitis SK321

66.667

100

0.667
  comA Streptococcus gordonii str. Challis substr. CH1

66.547

100

0.667
  comA Streptococcus pneumoniae TIGR4

66.487

100

0.665

Multiple sequence alignment