Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   DQK99_RS02855 Genome accession   NZ_LS483448
Coordinates   526644..527381 (+) Length   245 a.a.
NCBI ID   WP_088794864.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836167     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 521644..532381
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQK99_RS02820 - 522574..522813 (-) 240 WP_001810235.1 hypothetical protein -
  DQK99_RS02825 - 522975..523262 (-) 288 WP_000777760.1 hypothetical protein -
  DQK99_RS02830 - 523272..523682 (-) 411 WP_001278299.1 HIT family protein -
  DQK99_RS02835 pptA 523750..524481 (+) 732 WP_000889925.1 ABC transporter ATP-binding protein Regulator
  DQK99_RS02840 - 524478..525527 (+) 1050 WP_111703773.1 ABC transporter permease -
  DQK99_RS02845 - 525695..526024 (-) 330 WP_000132572.1 hypothetical protein -
  DQK99_RS02850 - 526301..526639 (+) 339 WP_000682135.1 LytTR family DNA-binding domain-containing protein -
  DQK99_RS02855 comE/blpR 526644..527381 (+) 738 WP_088794864.1 response regulator transcription factor Regulator
  DQK99_RS02860 - 527395..528735 (+) 1341 WP_001017638.1 sensor histidine kinase -
  DQK99_RS02865 blpC 528777..528932 (-) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  DQK99_RS02870 - 528989..530350 (-) 1362 WP_001069091.1 bacteriocin secretion accessory protein -
  DQK99_RS02875 comA/nlmT 530361..532037 (-) 1677 WP_196299874.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28714.95 Da        Isoelectric Point: 6.5012

>NTDB_id=1141810 DQK99_RS02855 WP_088794864.1 526644..527381(+) (comE/blpR) [Streptococcus pneumoniae strain 4041STDY6836167]
MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCPRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INKLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=1141810 DQK99_RS02855 WP_088794864.1 526644..527381(+) (comE/blpR) [Streptococcus pneumoniae strain 4041STDY6836167]
ATGAGAATATTTGTTTTAGAGGATGATTTTTCCCAACAGACTAGAATTGAAACGACGATTGAGAAACTTTTGAAAGCACA
TCATATCATTCCTAGCTCTTTTGAGGTATTTGGCAAGCCGGACCAACTGCTGGCTGAAGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAAGAGATGAAGGGACTGGAAGTGGCTAGAAAGATTCGGGATCGGGAT
CCTTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCTTTTCGCTACCAAGTGTCTGCTTTGGA
CTACATTGATAAGGCCTTGTCAGCAGAGGAGTTTGAATCTCGGATCGAGACAGCCCTCCTCTATGCCAATAGTCAAGATA
GTAAAAGTCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCCCAATTTCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCGCCCAGAGCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTTTAGAGGA
GGTTTTCAAGCAGGAGCCCCGTCTCTTGCAGTGCCCCCGCTCTTTTCTCATCAATCCTGCAAATGTGGTGCATTTGGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCCCGTTATAAGGTCAGGGAAGTGTCTGAGGCC
ATCAATAAATTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.909

99.184

0.535
  comE/comE1 Streptococcus equinus JB1

43.038

96.735

0.416
  comE/comE2 Streptococcus equinus JB1

37.603

98.776

0.371

Multiple sequence alignment