Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DQL20_RS10385 Genome accession   NZ_LS483444
Coordinates   2080574..2081842 (-) Length   422 a.a.
NCBI ID   WP_006595397.1    Uniprot ID   E7S8U6
Organism   Streptococcus australis strain NCTC13166     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2075574..2086842
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL20_RS10345 (NCTC11371_02014) - 2076328..2076639 (-) 312 WP_006595405.1 DUF1292 domain-containing protein -
  DQL20_RS10350 (NCTC11371_02015) ruvX 2076657..2077076 (-) 420 WP_006595404.1 Holliday junction resolvase RuvX -
  DQL20_RS10355 (NCTC11371_02016) - 2077076..2077342 (-) 267 WP_006597020.1 IreB family regulatory phosphoprotein -
  DQL20_RS10360 (NCTC11371_02017) - 2077484..2078035 (-) 552 WP_006595402.1 hypothetical protein -
  DQL20_RS10365 (NCTC11371_02018) - 2078047..2078640 (-) 594 WP_006595401.1 SP0191 family lipoprotein -
  DQL20_RS10375 (NCTC11371_02019) spx 2078825..2079223 (-) 399 WP_006595399.1 transcriptional regulator Spx -
  DQL20_RS10380 (NCTC11371_02020) recA 2079311..2080453 (-) 1143 WP_006595398.1 recombinase RecA Machinery gene
  DQL20_RS10385 (NCTC11371_02021) cinA 2080574..2081842 (-) 1269 WP_006595397.1 competence/damage-inducible protein A Machinery gene
  DQL20_RS10390 (NCTC11371_02022) - 2082219..2083256 (+) 1038 WP_006595395.1 S66 peptidase family protein -
  DQL20_RS10395 (NCTC11371_02023) - 2083312..2083875 (-) 564 WP_006595394.1 DNA-3-methyladenine glycosylase I -
  DQL20_RS10400 (NCTC11371_02024) ruvA 2083885..2084478 (-) 594 WP_006595393.1 Holliday junction branch migration protein RuvA -
  DQL20_RS10405 (NCTC11371_02025) mutL 2084499..2086448 (-) 1950 WP_006595392.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45011.20 Da        Isoelectric Point: 4.9404

>NTDB_id=1141761 DQL20_RS10385 WP_006595397.1 2080574..2081842(-) (cinA) [Streptococcus australis strain NCTC13166]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYYHVAVGDNEGRLFSTIETASKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELVFDPTALAKLDTFFASRPDYVRTPNNERQAQLIAGSIPLQNRTGLAVGGLIEVDGVTYVVLPGPPSELKPM
VNEQLVPHLTTGEQLFSRVLRFFGIGESQLVTILADIIEKQSDPTVAPYAKTGEVTLRLSTKAKDQASADAKLDVLEKEI
LSRHTLDHQPLHELFYGYGDDNSMAKVAFDLLKGTGKTITAAESLTAGLFQATLADFSGASSIFAGGFVTYSLEEKSKML
SIPAQELEQHGVVSHFTAQAMASQARKLTGSDYGVSLTGVAGPDSLEGHPAGTVFIGLATPNGVDSVQVNIAGRSRADVR
EIAVLHAFNLVRLAVLNGENLV

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=1141761 DQL20_RS10385 WP_006595397.1 2080574..2081842(-) (cinA) [Streptococcus australis strain NCTC13166]
ATGAAGGCGGAAATTATTGCAGTTGGAACAGAAATTCTAACAGGACAAATTGTCAACACCAATGCTCAGTTCTTGTCTGA
AAAATTGGCTAGTTTAGGGATTGATGTCTATTATCATGTGGCGGTAGGAGATAATGAAGGTCGTCTCTTCTCGACCATTG
AGACAGCTTCAAAACGCAGTGATTTGGTGATTTTATGTGGTGGACTTGGGCCAACAGAGGATGATTTGACCAAGCAAACC
CTTGCTAAGTTTTTAGGGAAAGAACTGGTTTTTGATCCAACAGCGCTTGCCAAACTCGACACCTTCTTTGCCAGTCGCCC
TGATTATGTACGGACGCCCAATAATGAGCGACAAGCACAATTGATTGCCGGTTCAATCCCCCTTCAAAACCGTACAGGTC
TCGCGGTTGGAGGTTTGATTGAAGTCGATGGTGTGACCTATGTCGTTCTACCTGGTCCACCAAGTGAGTTAAAACCCATG
GTCAATGAACAATTGGTGCCTCATTTGACAACAGGGGAGCAGCTCTTTTCAAGAGTCTTGCGCTTCTTTGGGATTGGGGA
AAGCCAGCTGGTTACGATCCTAGCAGATATCATTGAAAAGCAGAGTGATCCGACGGTGGCCCCTTATGCCAAGACAGGAG
AAGTGACCTTGCGTCTGTCTACAAAGGCGAAGGATCAAGCCTCAGCGGATGCGAAGCTCGATGTCTTAGAAAAGGAAATC
TTATCACGCCACACCCTGGATCATCAACCCTTGCATGAACTGTTTTACGGTTATGGGGATGACAATTCGATGGCCAAGGT
GGCCTTTGATCTCTTGAAAGGGACTGGTAAGACCATTACAGCTGCAGAAAGCCTGACGGCTGGCCTTTTCCAAGCGACTT
TGGCAGATTTTTCAGGGGCGTCCAGCATCTTCGCGGGTGGTTTTGTCACCTATAGTCTGGAAGAAAAAAGCAAGATGTTG
TCTATTCCAGCTCAAGAGTTAGAGCAACATGGAGTGGTGTCTCACTTTACAGCTCAAGCCATGGCTTCACAGGCCCGTAA
GTTAACAGGATCCGATTATGGTGTTAGCTTGACCGGAGTTGCGGGGCCAGATAGTCTAGAAGGGCACCCAGCAGGGACTG
TCTTTATCGGACTTGCGACTCCAAATGGAGTGGATAGTGTCCAAGTCAATATCGCTGGACGTAGCCGGGCGGATGTCCGC
GAAATTGCAGTCCTTCATGCCTTTAATTTGGTACGCTTGGCTGTATTAAATGGTGAAAATTTGGTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-412)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E7S8U6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.82

98.815

0.739
  cinA Streptococcus mitis NCTC 12261

74.82

98.815

0.739
  cinA Streptococcus pneumoniae TIGR4

73.621

98.815

0.727
  cinA Streptococcus pneumoniae Rx1

73.621

98.815

0.727
  cinA Streptococcus pneumoniae R6

73.621

98.815

0.727
  cinA Streptococcus pneumoniae D39

73.381

98.815

0.725
  cinA Streptococcus mutans UA159

70.449

100

0.706
  cinA Streptococcus suis isolate S10

55.932

97.867

0.547
  cinA Bacillus subtilis subsp. subtilis str. 168

47.47

98.341

0.467

Multiple sequence alignment