Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DQN42_RS08980 Genome accession   NZ_LS483436
Coordinates   1808528..1809796 (-) Length   422 a.a.
NCBI ID   WP_003077272.1    Uniprot ID   A0AAE8KBI8
Organism   Streptococcus intermedius strain NCTC11324     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1803528..1814796
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN42_RS08950 (NCTC11324_01803) - 1804246..1804551 (-) 306 WP_003075274.1 DUF1292 domain-containing protein -
  DQN42_RS08955 (NCTC11324_01804) ruvX 1804569..1804988 (-) 420 WP_003075276.1 Holliday junction resolvase RuvX -
  DQN42_RS08960 (NCTC11324_01805) - 1804988..1805254 (-) 267 WP_009569646.1 IreB family regulatory phosphoprotein -
  DQN42_RS08965 (NCTC11324_01806) - 1805560..1806117 (-) 558 WP_003077293.1 SP0191 family lipoprotein -
  DQN42_RS09945 (NCTC11324_01808) - 1806634..1806768 (-) 135 WP_003077174.1 hypothetical protein -
  DQN42_RS08970 (NCTC11324_01809) spx 1806850..1807248 (-) 399 WP_003026638.1 transcriptional regulator Spx -
  DQN42_RS08975 (NCTC11324_01810) recA 1807334..1808479 (-) 1146 WP_003077215.1 recombinase RecA Machinery gene
  DQN42_RS08980 (NCTC11324_01811) cinA 1808528..1809796 (-) 1269 WP_003077272.1 competence/damage-inducible protein A Machinery gene
  DQN42_RS08985 (NCTC11324_01812) - 1810089..1814003 (-) 3915 WP_003077296.1 Cna B-type domain-containing protein -
  DQN42_RS09890 - 1814353..1814674 (+) 322 Protein_1723 transposase -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45536.08 Da        Isoelectric Point: 6.1678

>NTDB_id=1141476 DQN42_RS08980 WP_003077272.1 1808528..1809796(-) (cinA) [Streptococcus intermedius strain NCTC11324]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGVDVYFQTVVGDNEDRLLSILEIARDRSNLVILTGGLGPTEDDLTKQT
LSKFLNRRLVFYQVAVEKLNRFFSSRPDYTRTPNNERQAQIVEGSTPLPNATGLAVGGLLEADGVTYVVLPGPPSELKPM
VNNELVPLLATGQKLYSRVLRFFGIGESQLVTLLGNLIDTQTDPTIAPYAKTGEVTLRLSTKASSQKEADVKFTHLEKKI
LAVQTFEKQQLADLFYAYGDDNSLGQTAFELLKKAGKTVTAAESLTAGLFQATLANFSGASKVFGGGFVTYGIEEKSQML
GIPLADLEMHGVVSAYTAEKMATQARKLTASDYAVSLTGVAGPDSLEGHPAGTVYIGLATADNVQSIQVNIAGRSRTDVR
KIAVLHAFNLLRKTLLKNENML

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=1141476 DQN42_RS08980 WP_003077272.1 1808528..1809796(-) (cinA) [Streptococcus intermedius strain NCTC11324]
ATGAAAGCAGAAATTATTGCTGTGGGTACTGAGATTTTGACTGGTCAGATTGTCAATACGAATGCTCAATTTTTATCTGA
AAAATTAGCGAGCTTGGGAGTAGATGTCTATTTCCAGACAGTGGTTGGAGATAATGAAGATCGTCTGTTATCCATTTTAG
AAATAGCTAGAGATCGTAGTAATTTAGTTATCTTGACAGGTGGTTTAGGTCCGACTGAAGACGACTTAACCAAGCAGACT
TTGTCAAAATTTTTGAATCGTAGGCTAGTCTTTTATCAAGTAGCTGTTGAAAAATTGAATCGTTTCTTCTCCAGCCGACC
GGACTATACTCGAACACCAAATAATGAGCGACAAGCTCAGATAGTAGAAGGCTCGACTCCTTTACCAAATGCGACTGGCT
TAGCTGTCGGAGGATTGTTAGAAGCAGACGGAGTGACCTATGTAGTCCTGCCTGGCCCCCCTAGTGAACTAAAGCCTATG
GTAAACAATGAGTTGGTTCCGCTTTTAGCAACTGGCCAAAAATTGTATTCGAGAGTCTTGCGTTTCTTTGGTATTGGGGA
GAGTCAATTAGTCACCCTTTTAGGAAACTTGATTGATACTCAGACGGATCCGACCATTGCTCCTTATGCTAAGACGGGAG
AAGTGACGTTGCGATTGTCGACCAAGGCCAGCAGTCAAAAGGAAGCAGATGTTAAGTTTACTCATCTGGAAAAGAAAATT
TTAGCAGTACAGACTTTTGAGAAACAACAATTAGCCGACCTTTTCTATGCTTATGGAGATGACAATTCTCTGGGACAGAC
AGCTTTTGAATTGTTGAAGAAAGCAGGCAAAACAGTCACAGCAGCTGAAAGTCTGACTGCGGGACTTTTTCAAGCGACTT
TAGCAAATTTTTCTGGAGCATCCAAGGTCTTTGGAGGTGGCTTTGTTACTTATGGCATAGAGGAGAAGAGTCAAATGTTA
GGCATTCCATTGGCAGATTTAGAAATGCATGGGGTAGTCTCAGCTTATACAGCAGAGAAAATGGCTACGCAAGCTAGGAA
ATTGACTGCTAGTGACTATGCGGTGAGTTTGACTGGAGTAGCAGGTCCAGATAGTTTAGAAGGCCATCCAGCAGGAACTG
TTTATATTGGCTTGGCAACTGCAGATAACGTTCAGTCTATTCAGGTTAATATTGCGGGGCGCAGTCGGACGGATGTACGT
AAAATAGCTGTGTTACATGCTTTCAATTTGTTGCGAAAAACTTTATTAAAAAATGAGAATATGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

75.12

99.052

0.744
  cinA Streptococcus pneumoniae TIGR4

73.684

99.052

0.73
  cinA Streptococcus mitis NCTC 12261

73.684

99.052

0.73
  cinA Streptococcus pneumoniae Rx1

73.445

99.052

0.727
  cinA Streptococcus pneumoniae R6

73.445

99.052

0.727
  cinA Streptococcus pneumoniae D39

73.206

99.052

0.725
  cinA Streptococcus mutans UA159

71.631

100

0.718
  cinA Streptococcus suis isolate S10

54.087

98.578

0.533
  cinA Bacillus subtilis subsp. subtilis str. 168

46.411

99.052

0.46

Multiple sequence alignment