Detailed information NTG1141446

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: DQN42_RS05175
• Genome accession: NZ_LS483436
• Coordinates: 1049398..1050102 (-)
• Length: 234 a.a.
• NCBI ID: WP_003076279.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain NCTC11324
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1044398..1055102

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN42_RS05160 (NCTC11324_01040)	-	1044967..1045953 (-)	987	WP_003076968.1	Gfo/Idh/MocA family protein	-
DQN42_RS05165 (NCTC11324_01042)	-	1046389..1047102 (-)	714	WP_003076424.1	DUF805 domain-containing protein	-
DQN42_RS05170 (NCTC11324_01043)	comEC/celB	1047180..1049414 (-)	2235	WP_014829690.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DQN42_RS05175 (NCTC11324_01044)	comEA/celA/cilE	1049398..1050102 (-)	705	WP_003076279.1	helix-hairpin-helix domain-containing protein	Machinery gene
DQN42_RS05180 (NCTC11324_01045)	smpB	1050270..1050737 (-)	468	WP_003076815.1	SsrA-binding protein SmpB	-
DQN42_RS05185 (NCTC11324_01046)	rnr	1050700..1053039 (-)	2340	WP_003076716.1	ribonuclease R	-
DQN42_RS05190 (NCTC11324_01047)	secG	1053130..1053363 (-)	234	WP_003024744.1	preprotein translocase subunit SecG	-
DQN42_RS05195	rpmG	1053403..1053552 (-)	150	WP_003034401.1	50S ribosomal protein L33	-
DQN42_RS05200 (NCTC11324_01048)	-	1053536..1054753 (-)	1218	WP_278043792.1	multidrug efflux MFS transporter	-

Sequence

Protein

• Length: 234 a.a.
• Molecular weight: 25420.77 Da
• Isoelectric Point: 9.1090

>NTDB_id=1141446 DQN42_RS05175 WP_003076279.1 1049398..1050102(-) (comEA/celA/cilE) [Streptococcus intermedius strain NCTC11324]
MLEVIVTKIKEYKILVALSLIGLIIAGFFMMTSKSARQSNVGDIAQETTNEKLERKETSTETKKKQQKEETESQKNLASE
EVEFLTVDVKGAVKNPGIYQLKKTSRINDAIQKAGGLTTDADSKSINLAQKLTDEAVIYVAAMGENVTNAASNNGQTLTK
DTNGTAAQKGNKVNLNKANLSDLQSISGIGQKRAQDILDYREANGKFNSVDDLKNVSGVGAKTLEKLKEYVTVD

Nucleotide

• Length: 705 bp

>NTDB_id=1141446 DQN42_RS05175 WP_003076279.1 1049398..1050102(-) (comEA/celA/cilE) [Streptococcus intermedius strain NCTC11324]
ATGTTAGAGGTAATCGTCACAAAAATCAAAGAGTATAAAATTTTAGTTGCTTTAAGCCTGATTGGTTTGATCATAGCAGG
ATTTTTTATGATGACTAGTAAATCTGCTAGACAATCTAATGTGGGAGATATTGCACAAGAGACCACAAATGAAAAACTAG
AACGGAAAGAAACTTCAACTGAAACGAAGAAAAAACAACAGAAAGAAGAAACAGAATCTCAAAAGAATTTAGCGAGTGAA
GAAGTGGAATTTTTAACTGTAGATGTTAAAGGTGCTGTTAAAAATCCAGGTATTTATCAATTAAAAAAAACGAGCCGTAT
CAATGATGCTATTCAAAAAGCGGGTGGACTAACAACAGACGCTGACAGCAAATCTATCAATTTGGCTCAAAAACTAACAG
ATGAGGCTGTGATTTATGTGGCAGCTATGGGTGAAAATGTAACAAATGCTGCAAGTAATAATGGACAAACTTTAACGAAA
GATACCAATGGAACTGCGGCACAAAAAGGGAATAAGGTCAATCTAAATAAGGCTAATTTGTCTGATTTACAGTCTATTTC
TGGTATCGGACAAAAGCGCGCCCAAGATATTTTAGATTATCGTGAGGCAAATGGAAAATTTAATTCTGTTGATGATCTTA
AAAATGTATCAGGAGTTGGTGCTAAAACATTAGAGAAATTGAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (87-140)

• Helix-hairpin-helix motif (HHH_3) (169-232)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus mitis SK321	49.789	100	0.504
comEA/celA/cilE	Streptococcus mitis NCTC 12261	50.215	99.573	0.5
comEA/celA/cilE	Streptococcus pneumoniae Rx1	49.785	99.573	0.496
comEA/celA/cilE	Streptococcus pneumoniae D39	49.785	99.573	0.496
comEA/celA/cilE	Streptococcus pneumoniae R6	49.785	99.573	0.496
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	49.785	99.573	0.496
comEA	Streptococcus thermophilus LMD-9	43.162	100	0.432
comEA	Lactococcus lactis subsp. cremoris KW2	38.627	99.573	0.385