Detailed information NTG1141445

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: DQN42_RS05170
• Genome accession: NZ_LS483436
• Coordinates: 1047180..1049414 (-)
• Length: 744 a.a.
• NCBI ID: WP_014829690.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain NCTC11324
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1042180..1054414

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN42_RS05145 (NCTC11324_01037)	-	1042506..1043780 (-)	1275	WP_003076495.1	dihydroorotase	-
DQN42_RS05150 (NCTC11324_01038)	-	1043792..1044262 (-)	471	WP_003072602.1	8-oxo-dGTP diphosphatase	-
DQN42_RS05155 (NCTC11324_01039)	-	1044289..1044942 (-)	654	WP_003072601.1	uracil-DNA glycosylase	-
DQN42_RS05160 (NCTC11324_01040)	-	1044967..1045953 (-)	987	WP_003076968.1	Gfo/Idh/MocA family protein	-
DQN42_RS05165 (NCTC11324_01042)	-	1046389..1047102 (-)	714	WP_003076424.1	DUF805 domain-containing protein	-
DQN42_RS05170 (NCTC11324_01043)	comEC/celB	1047180..1049414 (-)	2235	WP_014829690.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DQN42_RS05175 (NCTC11324_01044)	comEA/celA/cilE	1049398..1050102 (-)	705	WP_003076279.1	helix-hairpin-helix domain-containing protein	Machinery gene
DQN42_RS05180 (NCTC11324_01045)	smpB	1050270..1050737 (-)	468	WP_003076815.1	SsrA-binding protein SmpB	-
DQN42_RS05185 (NCTC11324_01046)	rnr	1050700..1053039 (-)	2340	WP_003076716.1	ribonuclease R	-
DQN42_RS05190 (NCTC11324_01047)	secG	1053130..1053363 (-)	234	WP_003024744.1	preprotein translocase subunit SecG	-
DQN42_RS05195	rpmG	1053403..1053552 (-)	150	WP_003034401.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 85290.35 Da
• Isoelectric Point: 10.2431

>NTDB_id=1141445 DQN42_RS05170 WP_014829690.1 1047180..1049414(-) (comEC/celB) [Streptococcus intermedius strain NCTC11324]
MSQWIKIFPIKPIYIAFLLVWLYFAIYQSNWLAGVGLIFLLIRLSRIYSLKEWFTTLMILACFAVFFLVRRELANRKIKV
EAPPVRQVAVLPDTIKVNGDSLSFRGKAKGQTYQIYYKLKSKKEKLAFQNLSSLVTLTVEGEFESPEKQRNFSGFDYQAY
LKTQGIYRILKVDQILSSQDRVSLQPFEWLSSWRRKALVFIKRNFPNPMSNYMTGFLFGALDTDFGEMNNLYSSLGIIHL
FALSGMQVGFFMEGFRKSLLRLGLTQEIVHKCQYPFSFFYAGMTGFSVSVVRSLIQKLLSQHGITKLDNFALTIMVLSLI
MPSFLLTAGGVLSCAYAFIISVLDFKGLTPYKKIIIESIVISLGILPILIFYFGEFQPWSILLTFVFSLIFDIVMLPGLT
IIFLVSPFIKLTQVNFLFECLESSIRWLASMFSRPVVLGKPNPLLLIAMLLVLAILYDIRQNKKWLIFLSLFLSLLFFVA
KFPLQNEITMIDVGKGDSIFMRDWRGSTVLIDVGGREEIRKKESWQERISSSNAERTLIPYLKSRGVDTIDTLVLTNPNS
DYAGDVLEVAKKFSIKKIFISRSSLNDADFLNKLKETRAFVHVVKQGDKLPIFDHHLQVLSGTNKNDQSLVLYGQFFRTR
FLFMSNLTEEDEVKLMQLYPKLKTDVLKVGQHGSQNSSSSKFLQQVRPVIALISTGKNNSSKSLSQETIERFNRLNTKIY
RTDKQGAIKFSGWTTWQLETVQQP

Nucleotide

• Length: 2235 bp

>NTDB_id=1141445 DQN42_RS05170 WP_014829690.1 1047180..1049414(-) (comEC/celB) [Streptococcus intermedius strain NCTC11324]
ATGTCACAGTGGATTAAGATATTTCCGATCAAACCAATTTACATTGCTTTTTTACTTGTCTGGTTATATTTTGCAATCTA
TCAAAGTAATTGGTTGGCAGGAGTGGGATTGATCTTTCTGTTAATTCGTCTTTCCCGCATATATTCGCTAAAAGAATGGT
TTACAACTTTAATGATTCTCGCTTGTTTTGCTGTTTTTTTCCTTGTTCGTAGGGAACTGGCGAATCGGAAGATAAAAGTA
GAAGCTCCTCCTGTAAGACAAGTTGCGGTTTTACCTGATACAATTAAGGTAAATGGAGATTCGCTTTCTTTTCGTGGTAA
AGCAAAAGGACAGACATATCAAATTTACTACAAATTGAAATCAAAAAAAGAAAAGTTGGCTTTTCAAAATCTATCCAGCC
TTGTCACATTAACTGTTGAGGGGGAATTTGAATCTCCTGAAAAGCAGCGCAATTTTTCTGGTTTTGATTATCAAGCCTAT
CTAAAAACACAAGGGATTTATCGAATTTTAAAGGTGGATCAAATTTTGTCTAGTCAAGATAGGGTTAGCCTCCAACCGTT
TGAGTGGCTGTCTAGCTGGCGAAGAAAAGCATTGGTTTTCATTAAGAGAAATTTCCCGAATCCAATGAGCAATTATATGA
CAGGGTTTTTGTTCGGAGCTTTGGATACAGATTTTGGTGAAATGAATAACCTTTATTCGAGCTTGGGAATTATTCATTTA
TTTGCATTGTCTGGTATGCAAGTTGGTTTTTTTATGGAAGGGTTTCGTAAGTCACTGTTGAGATTGGGGCTTACGCAGGA
AATAGTTCATAAGTGTCAATATCCATTTTCTTTTTTTTATGCTGGAATGACAGGTTTTTCAGTATCCGTTGTACGGAGTT
TAATCCAGAAATTATTGTCACAACACGGCATTACTAAGTTAGATAATTTTGCTTTAACAATAATGGTGTTGTCCTTGATT
ATGCCCTCCTTTCTTTTAACAGCAGGAGGAGTACTTTCTTGTGCGTATGCTTTTATCATTAGCGTTTTAGATTTTAAAGG
CCTGACTCCTTATAAAAAGATTATTATAGAGAGTATTGTCATTTCGCTTGGCATTTTACCAATTTTAATCTTTTATTTCG
GAGAATTTCAGCCCTGGTCTATTTTATTGACATTTGTTTTTTCGTTGATTTTCGATATAGTGATGTTACCGGGGCTAACG
ATAATTTTTCTTGTTTCCCCTTTCATAAAACTCACTCAAGTTAATTTTCTATTTGAATGCTTAGAAAGTAGCATTCGCTG
GTTAGCAAGTATGTTTAGCAGACCAGTCGTTCTTGGCAAACCTAATCCACTTTTGCTAATCGCTATGTTGCTTGTATTAG
CTATCTTGTATGATATTCGGCAAAATAAAAAATGGCTGATATTTCTTAGTCTGTTTCTTTCATTACTCTTTTTTGTAGCT
AAATTTCCTTTACAAAATGAAATCACAATGATTGATGTCGGGAAGGGAGATAGTATTTTTATGCGAGACTGGAGAGGGAG
CACTGTATTGATTGATGTTGGCGGACGTGAAGAAATTAGAAAAAAAGAAAGTTGGCAAGAACGTATAAGTAGTTCAAACG
CAGAGAGAACGCTGATTCCATATCTTAAAAGTCGTGGTGTAGATACGATTGATACTTTAGTCTTAACAAATCCAAATTCA
GATTATGCAGGAGATGTATTAGAAGTTGCTAAAAAGTTTTCGATAAAGAAAATTTTTATTTCCAGAAGTAGTTTGAATGA
TGCAGACTTTTTAAATAAATTAAAGGAGACAAGGGCATTTGTTCATGTCGTAAAACAAGGAGACAAACTTCCTATTTTTG
ATCATCATTTGCAAGTTCTTTCTGGTACGAATAAGAATGATCAATCGCTAGTTTTATATGGTCAATTTTTTCGTACAAGG
TTTTTATTTATGAGCAATTTAACAGAAGAGGATGAAGTAAAGCTAATGCAACTTTATCCAAAACTAAAAACAGATGTCTT
GAAGGTTGGGCAACATGGATCCCAAAATTCATCAAGTTCTAAGTTCTTACAGCAAGTAAGACCAGTGATTGCCCTCATCT
CTACTGGGAAAAACAATTCATCCAAATCGCTAAGTCAAGAAACAATTGAGCGATTCAATCGATTAAATACAAAGATCTAT
CGAACAGATAAACAGGGGGCTATTAAGTTTTCGGGTTGGACAACATGGCAATTAGAAACTGTTCAGCAACCATAG

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (31-175)

• Competence protein (Competence) (218-461)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	55.689	100	0.559
comEC/celB	Streptococcus mitis NCTC 12261	55.496	100	0.556
comEC/celB	Streptococcus pneumoniae TIGR4	54.485	100	0.547
comEC/celB	Streptococcus pneumoniae Rx1	53.949	100	0.542
comEC/celB	Streptococcus pneumoniae D39	53.949	100	0.542
comEC/celB	Streptococcus pneumoniae R6	53.949	100	0.542
comEC	Lactococcus lactis subsp. cremoris KW2	46.03	99.866	0.46