Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DQN75_RS08560 Genome accession   NZ_LS483420
Coordinates   1699165..1700436 (-) Length   423 a.a.
NCBI ID   WP_032459984.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC13739     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1694165..1705436
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN75_RS08525 (NCTC13739_01684) - 1694810..1695115 (-) 306 WP_111685299.1 DUF1292 domain-containing protein -
  DQN75_RS08530 (NCTC13739_01685) ruvX 1695127..1695546 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  DQN75_RS08535 (NCTC13739_01686) - 1695543..1695812 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  DQN75_RS08545 (NCTC13739_01688) - 1695985..1697118 (-) 1134 WP_014635671.1 ISAs1-like element IS1548 family transposase -
  DQN75_RS08550 (NCTC13739_01689) spx 1697251..1697649 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  DQN75_RS08555 (NCTC13739_01690) recA 1697940..1699076 (-) 1137 WP_111685303.1 recombinase RecA Machinery gene
  DQN75_RS08560 (NCTC13739_01691) cinA 1699165..1700436 (-) 1272 WP_032459984.1 competence/damage-inducible protein A Machinery gene
  DQN75_RS08565 (NCTC13739_01692) - 1700505..1701065 (-) 561 WP_023611248.1 DNA-3-methyladenine glycosylase I -
  DQN75_RS08570 (NCTC13739_01693) ruvA 1701075..1701671 (-) 597 WP_011285268.1 Holliday junction branch migration protein RuvA -
  DQN75_RS08575 (NCTC13739_01694) - 1701673..1702893 (-) 1221 WP_111675058.1 MDR family MFS transporter -
  DQN75_RS08580 (NCTC13739_01695) mutL 1702904..1704886 (-) 1983 WP_111685305.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46018.75 Da        Isoelectric Point: 4.8322

>NTDB_id=1141025 DQN75_RS08560 WP_032459984.1 1699165..1700436(-) (cinA) [Streptococcus pyogenes strain NCTC13739]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVITTASQRSDLVILCGGLGPTKDDLTKQT
LAKYLRRDLVYDEQACQKLDDFFAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQ
LLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGLPLEELKSHGVVSAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRLDV
RYIATLHAFNMVRKTLLKLENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1141025 DQN75_RS08560 WP_032459984.1 1699165..1700436(-) (cinA) [Streptococcus pyogenes strain NCTC13739]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGACAACGAGGAGCGTTTACTTTCAGTGATTA
CAACTGCTAGTCAGCGTAGTGACTTGGTCATTTTATGCGGTGGCCTTGGTCCAACGAAAGATGATTTAACCAAACAAACT
TTAGCAAAGTACCTTAGGAGAGACTTGGTTTATGATGAGCAAGCTTGTCAGAAACTAGATGACTTTTTTGCTAAGCGCAA
GCCTTCATCACGGACACCAAATAATGAGCGACAGGCACAAGTGATTGAAGGGTCAATCCCTTTGCCAAATAAAACTGGTC
TTGCGGTTGGTGGGTTCATTACAGTCGATGGTATTAGTTATGTTGTCTTACCGGGTCCTCCAAGTGAATTGAAGCCGATG
GTAAATGAAGAATTGGTACCACTTCTGTCAAAACAATACAGTACATTGTATTCAAAGGTACTACGCTTTTTTGGTATTGG
GGAAAGTCAGTTGGTAACAGTCTTGTCAGATTTTATTGAGAATCAAACTGATCCAACCATTGCTCCGTATGCTAAGACTG
GCGAAGTGACTCTTCGCTTATCAACAAAAACTGAAAACCAAGCTCTGGCAGATAAAAAGTTAGGTCAGCTAGAAGCGCAG
CTACTATCCCGAAAAACTCTTGAAGGTCAACCCTTAGCTGATGTCTTTTATGGCTATGGGGAGGATAATTCCTTAGCGCG
CGAGACATTTGAGCTCTTAGTAAAATATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCCTTCCTTTAGAGGAGTTGAAATCGCATGGCGTTGTTAGTGCTTATACAGCCGAGGGGATGGCGGAGCAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATAAAGGTTTTGATTAGCGGGCGAAGTCGTTTGGATGTG
CGCTATATCGCTACTTTACATGCCTTTAATATGGTCCGTAAAACTTTATTAAAACTTGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

69.976

100

0.7
  cinA Streptococcus mitis SK321

69.784

98.582

0.688
  cinA Streptococcus mitis NCTC 12261

69.305

98.582

0.683
  cinA Streptococcus pneumoniae TIGR4

68.345

98.582

0.674
  cinA Streptococcus pneumoniae Rx1

68.345

98.582

0.674
  cinA Streptococcus pneumoniae R6

68.345

98.582

0.674
  cinA Streptococcus pneumoniae D39

68.106

98.582

0.671
  cinA Streptococcus suis isolate S10

53.365

98.345

0.525
  cinA Bacillus subtilis subsp. subtilis str. 168

46.89

98.818

0.463

Multiple sequence alignment