Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYC   Type   Machinery gene
Locus tag   DQM95_RS01030 Genome accession   NZ_LS483397
Coordinates   161081..161347 (+) Length   88 a.a.
NCBI ID   WP_037592920.1    Uniprot ID   -
Organism   Streptococcus uberis strain NCTC3858     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 125763..181096 161081..161347 within 0


Gene organization within MGE regions


Location: 125763..181096
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM95_RS00780 (NCTC3858_00159) - 125763..127208 (-) 1446 WP_037592992.1 recombinase family protein -
  DQM95_RS00785 (NCTC3858_00160) - 127358..127807 (-) 450 WP_037592991.1 Ltp family lipoprotein -
  DQM95_RS00790 (NCTC3858_00161) - 127860..128237 (-) 378 WP_037593023.1 ImmA/IrrE family metallo-endopeptidase -
  DQM95_RS00795 (NCTC3858_00162) - 128221..128583 (-) 363 WP_037592990.1 helix-turn-helix domain-containing protein -
  DQM95_RS00800 (NCTC3858_00163) - 128774..128974 (+) 201 WP_037592989.1 helix-turn-helix transcriptional regulator -
  DQM95_RS00805 (NCTC3858_00164) - 129021..129746 (+) 726 WP_037592987.1 phage antirepressor KilAC domain-containing protein -
  DQM95_RS00810 (NCTC3858_00165) - 129758..130099 (+) 342 WP_037592986.1 hypothetical protein -
  DQM95_RS00815 (NCTC3858_00166) - 130100..130312 (-) 213 WP_037592984.1 hypothetical protein -
  DQM95_RS00820 - 130462..130647 (+) 186 WP_037592983.1 helix-turn-helix transcriptional regulator -
  DQM95_RS10020 (NCTC3858_00167) - 130710..130868 (+) 159 WP_170123115.1 BOW99_gp33 family protein -
  DQM95_RS00830 (NCTC3858_00168) - 131395..131676 (+) 282 WP_037592981.1 hypothetical protein -
  DQM95_RS00835 (NCTC3858_00169) - 131676..131936 (+) 261 WP_037592980.1 hypothetical protein -
  DQM95_RS10145 (NCTC3858_00170) - 131949..132080 (+) 132 WP_269460017.1 hypothetical protein -
  DQM95_RS00840 (NCTC3858_00171) - 132084..132263 (+) 180 WP_037592979.1 hypothetical protein -
  DQM95_RS00845 (NCTC3858_00172) bet 132260..133033 (+) 774 WP_037592978.1 phage recombination protein Bet -
  DQM95_RS00850 (NCTC3858_00173) - 133044..134072 (+) 1029 WP_037592977.1 DUF1351 domain-containing protein -
  DQM95_RS00855 (NCTC3858_00174) - 134075..134344 (+) 270 WP_037592976.1 hypothetical protein -
  DQM95_RS00860 (NCTC3858_00175) - 134354..134677 (+) 324 WP_037592975.1 hypothetical protein -
  DQM95_RS00865 (NCTC3858_00176) - 134674..134853 (+) 180 WP_037592974.1 hypothetical protein -
  DQM95_RS00875 (NCTC3858_00177) - 135323..135664 (+) 342 WP_037592972.1 hypothetical protein -
  DQM95_RS00880 (NCTC3858_00178) - 135664..136092 (+) 429 WP_037592971.1 RusA family crossover junction endodeoxyribonuclease -
  DQM95_RS00885 (NCTC3858_00179) - 136083..136397 (+) 315 WP_037592970.1 DUF1372 family protein -
  DQM95_RS00890 (NCTC3858_00180) - 136394..136846 (+) 453 WP_037592969.1 YopX family protein -
  DQM95_RS00895 (NCTC3858_00181) - 136827..137072 (+) 246 WP_037592968.1 hypothetical protein -
  DQM95_RS00900 (NCTC3858_00182) - 137069..137383 (+) 315 WP_037592967.1 hypothetical protein -
  DQM95_RS00905 (NCTC3858_00183) - 137458..137874 (+) 417 WP_037592964.1 DUF1492 domain-containing protein -
  DQM95_RS00910 (NCTC3858_00184) terS 138034..138765 (+) 732 WP_037592962.1 phage terminase small subunit -
  DQM95_RS00915 (NCTC3858_00185) - 138734..140032 (+) 1299 WP_037592960.1 PBSX family phage terminase large subunit -
  DQM95_RS00920 (NCTC3858_00186) - 140044..141555 (+) 1512 WP_331813043.1 phage portal protein -
  DQM95_RS00925 (NCTC3858_00187) - 141560..143182 (+) 1623 WP_037592958.1 phage minor capsid protein -
  DQM95_RS00930 (NCTC3858_00188) - 143179..143370 (+) 192 WP_037592956.1 hypothetical protein -
  DQM95_RS00935 (NCTC3858_00189) - 143421..143693 (+) 273 WP_037592949.1 hypothetical protein -
  DQM95_RS00940 (NCTC3858_00190) - 143861..144424 (+) 564 WP_037592944.1 phage scaffolding protein -
  DQM95_RS00945 (NCTC3858_00191) - 144445..145314 (+) 870 WP_037592941.1 hypothetical protein -
  DQM95_RS10025 (NCTC3858_00192) - 145328..145486 (+) 159 WP_000032859.1 hypothetical protein -
  DQM95_RS00950 (NCTC3858_00193) - 145492..145692 (+) 201 WP_001051385.1 hypothetical protein -
  DQM95_RS00955 (NCTC3858_00194) - 145707..146117 (+) 411 WP_111685886.1 hypothetical protein -
  DQM95_RS00960 (NCTC3858_00195) - 146104..146445 (+) 342 WP_037592938.1 putative minor capsid protein -
  DQM95_RS00965 (NCTC3858_00196) - 146445..146807 (+) 363 WP_037592937.1 minor capsid protein -
  DQM95_RS00970 (NCTC3858_00197) - 146804..147205 (+) 402 WP_111685887.1 minor capsid protein -
  DQM95_RS00975 (NCTC3858_00198) - 147206..147667 (+) 462 WP_037592936.1 phage tail tube protein -
  DQM95_RS00980 (NCTC3858_00199) - 147730..148098 (+) 369 WP_006739703.1 hypothetical protein -
  DQM95_RS00985 (NCTC3858_00200) - 148100..148699 (+) 600 WP_037592934.1 Gp15 family bacteriophage protein -
  DQM95_RS00990 (NCTC3858_00201) - 148715..152092 (+) 3378 WP_037592930.1 tape measure protein -
  DQM95_RS00995 (NCTC3858_00202) - 152089..153531 (+) 1443 WP_111685888.1 distal tail protein Dit -
  DQM95_RS01000 (NCTC3858_00203) - 153531..156311 (+) 2781 WP_037592928.1 phage tail spike protein -
  DQM95_RS01005 (NCTC3858_00204) - 156325..158334 (+) 2010 WP_037592924.1 DUF859 domain-containing protein -
  DQM95_RS01010 (NCTC3858_00205) - 158347..158745 (+) 399 WP_037592923.1 DUF1366 domain-containing protein -
  DQM95_RS10030 (NCTC3858_00206) - 158808..158966 (+) 159 WP_170123116.1 hypothetical protein -
  DQM95_RS01015 (NCTC3858_00207) - 158979..159449 (+) 471 WP_111685889.1 phage holin family protein -
  DQM95_RS10190 (NCTC3858_00208) - 159451..160164 (+) 714 WP_037592922.1 peptidoglycan amidohydrolase family protein -
  DQM95_RS01030 (NCTC3858_00211) comYC 161081..161347 (+) 267 WP_037592920.1 competence type IV pilus major pilin ComGC Machinery gene
  DQM95_RS01035 (NCTC3858_00212) comGD 161298..161735 (+) 438 WP_111685890.1 competence type IV pilus minor pilin ComGD -
  DQM95_RS01040 (NCTC3858_00213) comGE 161707..162006 (+) 300 WP_111685891.1 competence type IV pilus minor pilin ComGE -
  DQM95_RS01045 (NCTC3858_00214) comGF 161966..162421 (+) 456 WP_037592918.1 competence type IV pilus minor pilin ComGF -
  DQM95_RS01050 (NCTC3858_00215) comGG 162399..162758 (+) 360 WP_037592916.1 competence type IV pilus minor pilin ComGG -
  DQM95_RS01055 (NCTC3858_00216) comYH 162803..163759 (+) 957 WP_037592915.1 class I SAM-dependent methyltransferase Machinery gene
  DQM95_RS01060 (NCTC3858_00217) - 163815..165005 (+) 1191 WP_037592914.1 acetate kinase -
  DQM95_RS01065 (NCTC3858_00218) - 165123..165326 (+) 204 WP_012657682.1 helix-turn-helix transcriptional regulator -
  DQM95_RS01070 - 165328..165780 (+) 453 WP_037592912.1 hypothetical protein -
  DQM95_RS01075 (NCTC3858_00220) - 165789..166442 (+) 654 WP_012657684.1 CPBP family intramembrane glutamic endopeptidase -
  DQM95_RS01080 (NCTC3858_00221) proC 166468..167238 (-) 771 WP_111685892.1 pyrroline-5-carboxylate reductase -
  DQM95_RS01085 (NCTC3858_00222) pepA 167260..168324 (-) 1065 WP_111686022.1 glutamyl aminopeptidase -
  DQM95_RS01090 (NCTC3858_00223) - 168473..168760 (+) 288 WP_037592911.1 DUF4651 domain-containing protein -
  DQM95_RS01095 (NCTC3858_00224) - 168753..169067 (+) 315 WP_037592909.1 thioredoxin family protein -
  DQM95_RS01100 (NCTC3858_00225) ytpR 169086..169712 (+) 627 WP_037592907.1 YtpR family tRNA-binding protein -
  DQM95_RS01105 (NCTC3858_00226) - 169906..173715 (+) 3810 WP_111685893.1 GH32 C-terminal domain-containing protein -
  DQM95_RS01110 (NCTC3858_00227) ssbA 173879..174277 (+) 399 WP_012657691.1 single-stranded DNA-binding protein Machinery gene
  DQM95_RS01115 (NCTC3858_00228) - 174769..175728 (+) 960 WP_111685894.1 ABC transporter substrate-binding protein -
  DQM95_RS01120 (NCTC3858_00229) - 175745..176707 (+) 963 WP_037592900.1 ABC transporter substrate-binding protein -
  DQM95_RS01125 (NCTC3858_00230) - 176744..177628 (+) 885 WP_037592899.1 ABC transporter permease -
  DQM95_RS01130 (NCTC3858_00231) - 177637..178440 (+) 804 WP_046388461.1 ABC transporter ATP-binding protein -
  DQM95_RS01135 (NCTC3858_00232) - 178733..180787 (+) 2055 WP_037592898.1 transcription antiterminator -
  DQM95_RS01140 (NCTC3858_00233) - 180788..181096 (+) 309 WP_037592897.1 PTS sugar transporter subunit IIB -

Sequence


Protein


Download         Length: 88 a.a.        Molecular weight: 10006.65 Da        Isoelectric Point: 8.3979

>NTDB_id=1140146 DQM95_RS01030 WP_037592920.1 161081..161347(+) (comYC) [Streptococcus uberis strain NCTC3858]
MLMVLLIISVLMLLFIPNLSKQKEKVTDKGNAAVVKIVENQAELYELNEGKKPSLSELVQKGNISDKQQKAYNDYYQKHN
DESPILSK

Nucleotide


Download         Length: 267 bp        

>NTDB_id=1140146 DQM95_RS01030 WP_037592920.1 161081..161347(+) (comYC) [Streptococcus uberis strain NCTC3858]
ATGCTAATGGTCCTTCTGATCATCAGCGTGCTCATGCTCTTATTTATTCCCAATTTAAGCAAGCAAAAAGAAAAGGTAAC
AGATAAAGGAAATGCTGCAGTTGTGAAAATTGTAGAAAATCAAGCGGAGCTCTATGAATTGAATGAAGGGAAAAAACCTA
GCTTAAGTGAGCTAGTACAAAAAGGAAATATTAGTGACAAACAACAAAAAGCTTATAATGACTATTATCAAAAACATAAT
GACGAGAGTCCAATACTATCAAAGTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

67.857

95.455

0.648

  comGC/cglC Streptococcus pneumoniae Rx1

60

90.909

0.545

  comGC/cglC Streptococcus pneumoniae D39

60

90.909

0.545

  comGC/cglC Streptococcus pneumoniae R6

60

90.909

0.545

  comGC/cglC Streptococcus pneumoniae TIGR4

60.759

89.773

0.545

  comYC Streptococcus suis isolate S10

55.556

81.818

0.455

  comGC/cglC Streptococcus mitis SK321

60

73.864

0.443

  comGC Lactococcus lactis subsp. cremoris KW2

54.286

79.545

0.432

  comGC/cglC Streptococcus mitis NCTC 12261

53.521

80.682

0.432

  comYC Streptococcus mutans UA140

58.73

71.591

0.42

  comYC Streptococcus mutans UA159

58.73

71.591

0.42


Multiple sequence alignment